Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Adam M. Weidner"'
Autor:
Tina L. Beckett, Dana M. Niedowicz, Christa M. Studzinski, Adam M. Weidner, Robin L. Webb, Christopher J. Holler, Rachel R. Ahmed, Harry LeVine, III, M. Paul Murphy
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 3, Pp 449-456 (2010)
Sporadic inclusion body myositis (sIBM) is a common age-related inflammatory myopathy characterized by the presence of intracellular inclusions that contain the amyloid-β (Aβ) peptide, a derivative of the amyloid precursor protein (APP). Aβ is bel
Externí odkaz:
https://doaj.org/article/f9fd4d5436c54d78a6f802342f23cb4e
Autor:
M. Paul Murphy, Annadora J. Bruce-Keller, Tina L. Beckett, Kristen N. Kingry, Jeffrey N. Keller, Dana M. Niedowicz, Christa M. Studzinski, Thomas L. Platt, Adam M. Weidner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(3):439-444
Alzheimer's disease (AD) is the most common age-related neurodegenerative disease, affecting an estimated 5.3million people in the United States. While many factors likely contribute to AD progression, it is widely accepted that AD is driven by the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b25d167324ca19cde8aeb41ca820740
Autor:
Viorela Pop, M. Paul Murphy, Carl W. Cotman, Elizabeth Head, Christa M. Studzinski, Adam M. Weidner, Nicole C. Berchtold, Charles G. Glabe
Publikováno v:
Neurobiology of Aging. 33:108-120
The aged canine is a higher animal model that naturally accumulates β-amyloid (Aβ) and shows age-related cognitive decline. However, profiles of Aβ accumulation in different species (40 vs. 42), its assembly states, and Aβ precursor protein (APP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9070c20f7c1a7b32c02e32c6276cb0e1
https://doi.org/10.1016/j.neurobiolaging.2010.02.008
https://doi.org/10.1016/j.neurobiolaging.2010.02.008
Autor:
M. Paul Murphy, Adam M. Weidner, William R. Markesbery, Harry LeVine, Annadora J. Bruce-Keller, Jeffrey N. Keller, Sun Ok Fernandez-Kim, Kalavathi Dasuri, Philip J. Ebenezer, Le Zhang, Elena Gavilán
Publikováno v:
Journal of Alzheimer's Disease. 22:839-848
Recent studies have demonstrated a potential role for oligomeric forms of beta amyloid (Aβ) in the pathogenesis of Alzheimer’s disease (AD), although it remains unclear which aspects of AD may be mediated by oligomeric Aβ. In the present study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b23e75388349702cac472aeaede88f
https://doi.org/10.3233/jad-2010-101161
https://doi.org/10.3233/jad-2010-101161
Autor:
Sunita Gupta, Taryn E. Parrino, Harry LeVine, Jeffrey N. Keller, Philip J. Ebenezer, Adam M. Weidner, Annadora J. Bruce-Keller, Alecia G. Knight, William R. Markesbery
Publikováno v:
Antioxidants & Redox Signaling. 12:1371-1382
This study was undertaken to investigate the profile of NADPH oxidase (NOX) in the clinical progression of Alzheimer's disease (AD). Specifically, NOX activity and expression of the regulatory subunit p47phox and the catalytic subunit gp91phox was ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fbd9e74f05a52e773912fa841a2780
https://doi.org/10.1089/ars.2009.2823
https://doi.org/10.1089/ars.2009.2823
Autor:
Tina L. Beckett, Jeffrey N. Keller, Harry LeVine, Marta S. Mendiondo, Richard J. Kryscio, Irfan Baig, Dana M. Niedowicz, Sergey V. Matveev, M. Paul Murphy, Adam M. Weidner
Publikováno v:
Annals of neurology. 72(4)
Deposition of the amyloid-β (Aβ) peptide in neuritic plaques is a requirement for the diagnosis of Alzheimer disease (AD). Although the continued development of in vivo imaging agents such as Pittsburgh compound B (PiB) is promising, the diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdc9d784d79e0536273a553baa28aaf
https://pubmed.ncbi.nlm.nih.gov/23109151
https://pubmed.ncbi.nlm.nih.gov/23109151
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d90645c57afaae8a38b94213bd162ac
https://doi.org/10.1096/fasebj.25.1_supplement.lb513
https://doi.org/10.1096/fasebj.25.1_supplement.lb513
Publikováno v:
Neuroscience letters. 497(1)
Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047d70e67e276d816f6259059c216580
https://pubmed.ncbi.nlm.nih.gov/21504780
https://pubmed.ncbi.nlm.nih.gov/21504780
The cellular nucleic acid binding protein (CNBP) is a ubiquitously expressed protein involved in regulation of transcription and translation. CNBP, and its encoding gene ZNF9, have been shown to be involved in type 2 myotonic dystrophy. Both Alzheime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7320dde4b61b20570f294dd179c09c
https://europepmc.org/articles/PMC2921452/
https://europepmc.org/articles/PMC2921452/
Autor:
Adam M. Weidner, Harry LeVine, Dana M. Niedowicz, M. Paul Murphy, Rachel R. Ahmed, Christopher J. Holler, Christa M. Studzinski, Robin L. Webb, Tina L. Beckett
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 3, Pp 449-456 (2010)
Sporadic inclusion body myositis (sIBM) is a common age-related inflammatory myopathy characterized by the presence of intracellular inclusions that contain the amyloid-beta (Abeta) peptide, a derivative of the amyloid precursor protein (APP). Abeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d508d897f2ba247532afe886cf0ec6d5
https://pubmed.ncbi.nlm.nih.gov/20493261
https://pubmed.ncbi.nlm.nih.gov/20493261