Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adam M. Pickrum"'
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Achromobacter xylosoxidans is an opportunistic pathogen implicated in a wide variety of human infections including the ability to colonize the lungs of cystic fibrosis (CF) patients. The role of A. xylosoxidans in human pathology remains con
Externí odkaz:
https://doaj.org/article/c32c5c8c4c27470a8bd36eb9dd331d92
Autor:
Brandon M. Wills, Preeti Garai, Molly O. Riegert, Felix T. Sanchez, Adam M. Pickrum, Dara W. Frank, Kenneth L. Brockman
Publikováno v:
Infection and Immunity.
Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c6aef9125dd2763e2d45439d1da76a
https://doi.org/10.1128/iai.00037-23
https://doi.org/10.1128/iai.00037-23
Publikováno v:
Microbiology spectrum. 10(4)
Achromobacter xylosoxidans is an opportunistic pathogen implicated in a wide variety of human infections including the ability to colonize the lungs of cystic fibrosis (CF) patients. The role of A. xylosoxidans in human pathology remains controversia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6782dde994f6b0013d37eeae636a24b0
https://pubmed.ncbi.nlm.nih.gov/35856670
https://pubmed.ncbi.nlm.nih.gov/35856670
Autor:
Maxx H. Tessmer, Aaron T. Dirck, Dara W. Frank, Nathan A. Ledeboer, Adam M. Pickrum, John R. Kirby, Molly O. Riegert, Orlando DeLeon, Julie Biller
Publikováno v:
Infect Immun
Achromobacter xylosoxidans is increasingly recognized as a colonizer of cystic fibrosis (CF) patients, but the role that A. xylosoxidans plays in pathology remains unknown. This knowledge gap is largely due to the lack of model systems available to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c1951f239564281c2ec1df215cfd92
https://doi.org/10.1128/iai.00136-20
https://doi.org/10.1128/iai.00136-20
Autor:
Jimmy B. Feix, Jens Meiler, Rocco Moretti, David M. Anderson, Dara W. Frank, Adam M. Pickrum, Maxx H. Tessmer, Molly O. Riegert
Publikováno v:
Proceedings of the National Academy of Sciences. 115:525-530
ExoU is a type III-secreted cytotoxin expressing A2 phospholipase activity when injected into eukaryotic target cells by the bacterium Pseudomonas aeruginosa. The enzymatic activity of ExoU is undetectable in vitro unless ubiquitin, a required cofact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddef66f6cdb7a025f639b5e6def0e063
https://doi.org/10.1073/pnas.1716861115
https://doi.org/10.1073/pnas.1716861115
Autor:
Adam M. Pickrum, Stephanie L. Kellogg, Olivia Koehn, Benjamin D Labbe, Yao Chen, Christopher J. Kristich, Cherisse L. Hall, Shama P. Mirza
Transmembrane Ser/Thr kinases containing extracellular PASTA (penicillin-binding protein [PBP] and Ser/Thr-associated) domains are ubiquitous among Actinobacteria and Firmicutes species. Such PASTA kinases regulate critical bacterial processes, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc947943b4302a0455177f4111b2a12
https://europepmc.org/articles/PMC6482931/
https://europepmc.org/articles/PMC6482931/
Publikováno v:
Journal of Bacteriology. 201
ExoU is a potent type III secretion system effector that is injected directly into mammalian cells by the opportunistic pathogen Pseudomonas aeruginosa. As a ubiquitin-activated phospholipase A2 (PLA2), ExoU exhibits cytotoxicity by cleaving membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4d1e4fbaa7c6e6a15afe1c4f8ed67
https://doi.org/10.1128/jb.00623-18
https://doi.org/10.1128/jb.00623-18
Autor:
Nita H. Salzman, Leou Ismael Banla, Adam M. Pickrum, Michael Hayward, Christopher J. Kristich
Publikováno v:
Infection and immunity. 87(5)
The human gastrointestinal tract (GIT) is inhabited by a dense microbial community of symbionts. Enterococci are among the earliest members of this community and remain core members of the GIT microbiota throughout life. Enterococci have also recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d0e7fc4b71561103fea673101c310f
https://pubmed.ncbi.nlm.nih.gov/30804098
https://pubmed.ncbi.nlm.nih.gov/30804098