Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Adam M. Dubis"'
Autor:
Gemma McIlwaine, MSc, Lajos Csincsik, PhD, Rachel Coey, BSc, Luping Wang, MD, PhD, Denise Fitzgerald, PhD, Jill Moffat, BSc, Adam M. Dubis, PhD, Gavin McDonnell, MD, Stella Hughes, MD, Tunde Peto, MD, PhD, Imre Lengyel, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100308- (2023)
Purpose: Multiple sclerosis (MS) is an inflammatory neurodegenerative disease of the central nervous system. Recent evidence suggests that degeneration of the inner layers of the retina occurs in MS. This study aimed to examine whether there are oute
Externí odkaz:
https://doaj.org/article/29d74be2e92f4d0d87867e974039b1d1
Publikováno v:
Light: Science & Applications, Vol 11, Iss 1, Pp 1-22 (2022)
Standardized imaging protocols, data analysis methods, reporting of metrics and trial outcome measures will enhance the impact of OCTA on improving retinal healthcare.
Externí odkaz:
https://doaj.org/article/75000d30ad7e4aa283f11983f1b987b5
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/d1cd62e88cc240ce913d79a7be26d7dc
Autor:
Sandeep Gopalakrishnan, Shima Mehrvar, Sepideh Maleki, Heather Schmitt, Phyllis Summerfelt, Adam M. Dubis, Betsy Abroe, Thomas B. Connor, Joseph Carroll, Wendy Huddleston, Mahsa Ranji, Janis T. Eells
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Photobiomodulation (PBM) by far-red (FR) to near-infrared (NIR) light has been demonstrated to restore the function of damaged mitochondria, increase the production of cytoprotective factors and prevent cell death. Our laboratory has shown t
Externí odkaz:
https://doaj.org/article/5aee5cb0967f41f39aadd3c6c79e264a
Autor:
Jasleen K. Jolly, Matthew P. Simunovic, Adam M. Dubis, Amandeep S. Josan, Anthony G. Robson, Marco P. Bellini, Edward Bloch, Odysseas Georgiadis, Lyndon da Cruz, Holly Bridge, Robert E. MacLaren
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Color vision is considered a marker of cone function and its assessment in patients with retinal pathology is complementary to the assessments of spatial vision [best-corrected visual acuity (BCVA)] and contrast detection (perimetry). Rod-cone and ch
Externí odkaz:
https://doaj.org/article/c156f1e0b34a4c5ca81c3258b2e34ebb
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6785 (2022)
Cyclic nucleotide-gated channel β 1 (CNGB1) encodes a subunit of the rod cyclic nucleotide-gated channel. Pathogenic variants in CNGB1 are responsible for 4% of autosomal recessive retinitis pigmentosa (RP). Several treatment strategies show promise
Externí odkaz:
https://doaj.org/article/5248d05b05704288833cdeb557a280fa
Autor:
Jasdeep S. Gill, Vasileios Theofylaktopoulos, Andreas Mitsios, Sarah Houston, Ahmed M. Hagag, Adam M. Dubis, Mariya Moosajee
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4198 (2022)
Pathogenic mutations in USH2A are a leading cause of visual loss secondary to non-syndromic or Usher syndrome-associated retinitis pigmentosa (RP). With an increasing number of RP-targeted clinical trials in progress, we sought to evaluate the photor
Externí odkaz:
https://doaj.org/article/1b9c51b24a7a4a338830c2f41a655757
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Vascular changes are increasingly recognized as important factors in the pathophysiology of neuroinflammatory disease, especially in multiple sclerosis (MS). The relatively novel technology of optical coherence tomography angiography (OCTA) images th
Externí odkaz:
https://doaj.org/article/6ace01b2fbea49bfbbcd4d844956d64a
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Mutations in the retinol dehydrogenase 12 (RDH12) gene are primarily associated with Leber congenital amaurosis (LCA) type 13, a severe early onset autosomal recessive retinal dystrophy. Only one family with a heterozygous variant, associated with mi
Externí odkaz:
https://doaj.org/article/4ca09fa6975646b1998443c3a828c37a
Publikováno v:
Therapeutic Advances in Ophthalmology, Vol 10 (2018)
Choroideremia is an X-linked inherited chorioretinal dystrophy leading to blindness by late adulthood. Choroideremia is caused by mutations in the CHM gene which encodes Rab escort protein 1 (REP1), an ubiquitously expressed protein involved in intra
Externí odkaz:
https://doaj.org/article/9126404745db46edaca0dde019b22a4d