Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Adam M Sandor"'
Autor:
Scott B Thompson, Adam M Sandor, Victor Lui, Jeffrey W Chung, Monique M Waldman, Robert A Long, Miriam L Estin, Jennifer L Matsuda, Rachel S Friedman, Jordan Jacobelli
Publikováno v:
eLife, Vol 9 (2020)
Lymphocyte migration is essential for the function of the adaptive immune system, and regulation of T cell entry into tissues is an effective therapy in autoimmune diseases. Little is known about the specific role of cytoskeletal effectors that media
Externí odkaz:
https://doaj.org/article/05848d0787a543cab416fc0649eb8077
Autor:
Christof C. Smith, Kelly S. Olsen, Kaylee M. Gentry, Maria Sambade, Wolfgang Beck, Jason Garness, Sarah Entwistle, Caryn Willis, Steven Vensko, Allison Woods, Misha Fini, Brandon Carpenter, Eric Routh, Julia Kodysh, Timothy O’Donnell, Carsten Haber, Kirsten Heiss, Volker Stadler, Erik Garrison, Adam M. Sandor, Jenny P. Y. Ting, Jared Weiss, Krzysztof Krajewski, Oliver C. Grant, Robert J. Woods, Mark Heise, Benjamin G. Vincent, Alex Rubinsteyn
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
Abstract Background Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation. The rationale for this design was to drive both humoral and cell
Externí odkaz:
https://doaj.org/article/1bd99e7646cd4b7097c6d90976a022a0
Autor:
Matthew D. Gallovic, Robert D. Junkins, Adam M. Sandor, Erik S. Pena, Christopher J. Sample, Ariel K. Mason, Leslee C. Arwood, Rebecca A. Sahm, Eric M. Bachelder, Kristy M. Ainslie, Gregory D. Sempowski, Jenny P.-Y. Ting
Publikováno v:
J Control Release
The COVID-19 pandemic highlights the need for effective vaccines against respiratory viruses. An ideal vaccine should induce robust and long-lasting responses with high manufacturing scalability. We used an adjuvant comprised of a Stimulator of Inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20087447a615e18aec17eddcf52b2b7a
https://doi.org/10.1016/j.jconrel.2022.05.017
https://doi.org/10.1016/j.jconrel.2022.05.017
CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes
Autor:
Adam M. Sandor, Robin S. Lindsay, Nathan Dyjack, Jennifer C. Whitesell, Cydney Rios, Brenda J. Bradley, Kathryn Haskins, David V. Serreze, Aron M. Geurts, Yi-Guang Chen, Max A. Seibold, Jordan Jacobelli, Rachel S. Friedman
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that affects more than 19 million people with incidence increasing rapidly worldwide. For T cells to effectively drive T1D, they must first traffic to the islets and extravasate through th
Externí odkaz:
https://doaj.org/article/84f626d760c74ffda3d49e544096b774
Autor:
Rebekah Watkins-Schulz, Cole J. Batty, Rebeca T. Stiepel, Megan E. Schmidt, Adam M. Sandor, Wei-Chun Chou, Kristy M. Ainslie, Eric M. Bachelder, Jenny P.-Y. Ting
Publikováno v:
Molecular pharmaceutics. 19(9)
Natural killer (NK) cells are an important member of the innate immune system and can participate in direct tumor cell killing in response to immunotherapies. One class of immunotherapy is stimulator of interferon gene (STING) agonists, which result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c6d71a1c31a60a1afc9b09d3117d6b
https://pubmed.ncbi.nlm.nih.gov/35913984
https://pubmed.ncbi.nlm.nih.gov/35913984
Publikováno v:
Clin Exp Immunol
Summary Inhibition of immune cell trafficking to the pancreatic islets during type 1 diabetes (T1D) has therapeutic potential, since targeting of T cell and B cell trafficking has been clinically effective in other autoimmune diseases. Trafficking to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b02e921d0c7700efce6a28d1a36b25
https://doi.org/10.1111/cei.13353
https://doi.org/10.1111/cei.13353
Autor:
Maria J. Sambade, Timothy O'Donnell, Brandon Carpenter, Julia Kodysh, Mark T. Heise, Christof C. Smith, Krzysztof Krajewski, Kirsten Heiss, Alex Rubinsteyn, Adam M. Sandor, Kaylee M. Gentry, Allison Woods, Kelly Olsen, Robert J. Woods, Sarah Entwistle, Caryn Willis, Volker Stadler, Jared Weiss, Wolfgang Beck, Misha Fini, Eric D. Routh, Oliver C. Grant, Jason Garness, Erik Garrison, Benjamin G. Vincent, Jenny P.-Y. Ting, Steven Vensko, Carsten Haber
Publikováno v:
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
There is an urgent need for a vaccine with efficacy against SARS-CoV-2. We hypothesize that peptide vaccines containing epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation would drive both humoral and cellular im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6ea26ff3562c69e7aa636ca14bdc4a
https://doi.org/10.1101/2020.06.04.135004
https://doi.org/10.1101/2020.06.04.135004
Autor:
Scott B Thompson, Adam M. Sandor, Jeffrey W Chung, Miriam L Estin, Jennifer L. Matsuda, Rachel S. Friedman, Victor Lui, Jordan Jacobelli, Robert A Long, Monique M Waldman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339c06ee5882c38e26fc80fee63ae01e
https://doi.org/10.7554/elife.58046.sa2
https://doi.org/10.7554/elife.58046.sa2
Autor:
Adam M. Sandor, Robert A Long, Jennifer L. Matsuda, Rachel S. Friedman, Monique M Waldman, Miriam L Estin, Scott B Thompson, Jeffrey W Chung, Victor Lui, Jordan Jacobelli
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Lymphocyte migration is essential for the function of the adaptive immune system, and regulation of T cell entry into tissues is an effective therapy in autoimmune diseases. Little is known about the specific role of cytoskeletal effectors that media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bbc0d065dd39774d8b73c5d03c7e79
https://pubmed.ncbi.nlm.nih.gov/32510333
https://pubmed.ncbi.nlm.nih.gov/32510333
Autor:
Jennifer C. Whitesell, Rachel S. Friedman, Kristen E. Dew, Jordan Jacobelli, Erika Rodriguez, Robin S. Lindsay, Dayna Tracy, Seth F. Yannacone, Adam M. Sandor, Brittany N. Basta
Publikováno v:
The Journal of experimental medicine. 218(10)
Understanding mechanisms of immune regulation is key to developing immunotherapies for autoimmunity and cancer. We examined the role of mononuclear phagocytes during peripheral T cell regulation in type 1 diabetes and melanoma. MERTK expression and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6a2109117788a379bdbcc965954d49
https://pubmed.ncbi.nlm.nih.gov/34415994
https://pubmed.ncbi.nlm.nih.gov/34415994