Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Adam M Goldsmith"'
Autor:
Paul D Bozyk, J Kelley Bentley, Antonia P Popova, Anuli C Anyanwu, Marisa D Linn, Adam M Goldsmith, Gloria S Pryhuber, Bethany B Moore, Marc B Hershenson
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130369 (2015)
Externí odkaz:
https://doaj.org/article/17feeb61e58d4832a7fc5bf40a143ec8
Autor:
Antonia P Popova, Tracy X Cui, Niko Kaciroti, Adam M Goldsmith, Marisa J Linn, Gloria S Pryhuber, Marc B Hershenson
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144122 (2015)
Isolation of tracheal aspirate mesenchymal stromal cells (MSCs) from premature infants has been associated with increased risk of bronchopulmonary dysplasia (BPD). MSCs show high levels of mRNAs encoding matricellular proteins, non-structural extrace
Externí odkaz:
https://doaj.org/article/7b1d6fe53c4b4d939dbb43a85ab34ced
Autor:
Paul D Bozyk, J Kelley Bentley, Antonia P Popova, Anuli C Anyanwu, Marisa D Linn, Adam M Goldsmith, Gloria S Pryhuber, Bethany B Moore, Marc B Hershenson
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31336 (2012)
In bronchopulmonary dysplasia (BPD), alveolar septae are thickened with collagen and α-smooth muscle actin, transforming growth factor (TGF)-β-positive myofibroblasts. Periostin, a secreted extracellular matrix protein, is involved in TGF-β-mediat
Externí odkaz:
https://doaj.org/article/03574b837b9f402e8b9a4a0327bc01c0
Autor:
Qiong Wang, David J Miller, Emily R Bowman, Deepti R Nagarkar, Dina Schneider, Ying Zhao, Marisa J Linn, Adam M Goldsmith, J Kelley Bentley, Umadevi S Sajjan, Marc B Hershenson
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002070 (2011)
Rhinovirus (RV), a single-stranded RNA picornavirus, is the most frequent cause of asthma exacerbations. We previously demonstrated in human bronchial epithelial cells that melanoma differentiation-associated gene (MDA)-5 and the adaptor protein for
Externí odkaz:
https://doaj.org/article/ff73928853e94b69a263526e4e017fbc
Autor:
Tracy X. Cui, Alexander E. Brady, Ying-Jian Zhang, Christina T. Fulton, Adam M. Goldsmith, Antonia P. Popova
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Premature infants with chronic lung disease, bronchopulmonary dysplasia (BPD), develop recurrent cough and wheezing following respiratory viral infections. The mechanisms driving the chronic respiratory symptoms are ill-defined. We have shown that hy
Externí odkaz:
https://doaj.org/article/95849cacabdf48a1a957f76fefc614fe
Autor:
Charu Rajput, Mingyuan Han, Tomoko Ishikawa, Jing Lei, Adam M. Goldsmith, Seyedehzarifeh Jazaeri, Claudia C. Stroupe, J. Kelley Bentley, Marc B. Hershenson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rhinovirus C (RV-C) infection is associated with severe asthma exacerbations. Since type 2 inflammation is an important disease mechanism in asthma, we hypothesized that RV-C infection, in contrast to RV-A, preferentially stimulates type 2 inflammati
Externí odkaz:
https://doaj.org/article/04400b607aaa40aba1e7044c4f3ffc8f
Autor:
Caitlin R. Jarman, Jing Lei, J. Kelley Bentley, Julie Lee, Charu Rajput, Tomoko Ishikawa, Marc B. Hershenson, Adam M. Goldsmith, Mingyuan Han, Jennifer Bermick
Publikováno v:
Allergy
Background Early-life wheezing-associated respiratory infection with human rhinovirus (RV) is associated with asthma development. RV infection of 6-day-old immature mice causes mucous metaplasia and airway hyperresponsiveness which is associated with
Autor:
Suraj Jaipalli, Marc B. Hershenson, Adam M. Goldsmith, J. Kelley Bentley, Tomoko Ishikawa, Jing Lei, Charu Rajput, Mingyuan Han, Joanna L. Hinde
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Asthma exacerbations are often caused by rhinovirus (RV). We and others have shown that Toll-like receptor 2 (TLR2), a membrane surface receptor that recognizes bacterial lipopeptides and lipoteichoic acid, is required and sufficient for RV-induced p
Autor:
Caitlin R. Jarman, Toby C. Lewis, Jing Lei, Marc B. Hershenson, Charu Rajput, J. Kelley Bentley, Tomoko Ishikawa, Mark J. Hoenerhoff, Mingyuan Han, Julie Lee, Adam M. Goldsmith, William T. Jackson
Publikováno v:
Mucosal Immunol
Activation of the inflammasome is a key function of the innate immune response that regulates inflammation in response to microbial substances. Inflammasome activation by human rhinovirus (RV), a major cause of asthma exacerbations, has not been well
Autor:
Seyedehzarifeh Jazaeri, Marc B. Hershenson, Caitlin R. Jarman, Julie Lee, Toby C. Lewis, Adam M. Goldsmith
Publikováno v:
Ann Allergy Asthma Immunol
BACKGROUND: Rhinovirus (RV) is the main cause of asthma exacerbations in children. Some studies reported that persons with asthma have attenuated interferon (IFN) responses to experimental RV infection compared with healthy individuals. However, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a9b44e3064241d32ca60a74e2a76f5
https://europepmc.org/articles/PMC8164986/
https://europepmc.org/articles/PMC8164986/