Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Adam M, Chaker"'
1
Akademický článek
AROMA: real-world global registry of dupilumab for chronic rhinosinusitis with nasal polyps
Autor: Shahid Siddiqui, Claus Bachert, Adam M. Chaker, Joseph K. Han, Peter W. Hellings, Anju T. Peters, Enrico Heffler, Siddhesh Kamat, Haixin Zhang, Scott Nash, Asif H. Khan, Lucia De Prado Gomez, Juby A. Jacob-Nara, Paul J. Rowe, Yamo Deniz
Publikováno v: ERJ Open Research, Vol 8, Iss 4 (2022)
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammatory disease of the nasal and paranasal sinuses. Dupilumab is a monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, wh
Externí odkaz: https://doaj.org/article/bd6ab2fceb3e47b39463130f9fec492b
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2
Akademický článek
Flow-Based CL-SMIA for the Quantification of Protein Biomarkers from Nasal Secretions in Comparison with Sandwich ELISA
Autor: Julia Neumair, Marie Kröger, Evamaria Stütz, Claudia Jerin, Adam M. Chaker, Carsten B. Schmidt-Weber, Michael Seidel
Publikováno v: Biosensors, Vol 13, Iss 7, p 670 (2023)
Protein biomarkers in nasal secretions can be used as a measure to differentiate between allergies, airway diseases and infections for non-invasive diagnostics. The point-of-care quantification of biomarker levels using flow-based microarray facilita
Externí odkaz: https://doaj.org/article/79aeee7920be462fa562894fc37875cb
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3
Akademický článek
TGF-β1 Drives Inflammatory Th Cell But Not Treg Cell Compartment Upon Allergen Exposure
Autor: Stephanie Musiol, Francesca Alessandrini, Constanze A. Jakwerth, Adam M. Chaker, Evelyn Schneider, Ferdinand Guerth, Benjamin Schnautz, Johanna Grosch, Ileana Ghiordanescu, Julia T. Ullmann, Josephine Kau, Mirjam Plaschke, Stefan Haak, Thorsten Buch, Carsten B. Schmidt-Weber, Ulrich M. Zissler
Publikováno v: Frontiers in Immunology, Vol 12 (2022)
TGF-β1 is known to have a pro-inflammatory impact by inducing Th9 and Th17 cells, while it also induces anti-inflammatory Treg cells (Tregs). In the context of allergic airway inflammation (AAI) its dual role can be of critical importance in influen
Externí odkaz: https://doaj.org/article/2107742a722a4451ab2e2106650214cb
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4
Akademický článek
Genome-Wide Gene Expression Analysis Reveals Unique Genes Signatures of Epithelial Reorganization in Primary Airway Epithelium Induced by Type-I, -II and -III Interferons
Autor: Anna Erb, Ulrich M. Zissler, Madlen Oelsner, Adam M. Chaker, Carsten B. Schmidt-Weber, Constanze A. Jakwerth
Publikováno v: Biosensors, Vol 12, Iss 11, p 929 (2022)
Biosensors such as toll-like receptors (TLR) induce the expression of interferons (IFNs) after viral infection that are critical to the first step in cell-intrinsic host defense mechanisms. Their differential influence on epithelial integrity genes,
Externí odkaz: https://doaj.org/article/347b9773ae1e4dd7b3c47cbc93dafea7
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6
Akademický článek
Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AITResearch in context
Autor: Ulrich M. Zissler, Constanze A. Jakwerth, Ferdinand M. Guerth, Lisa Pechtold, Juan Antonio Aguilar-Pimentel, Katharina Dietz, Kathrin Suttner, Guido Piontek, Bernhard Haller, Zuzana Hajdu, Matthias Schiemann, Carsten B. Schmidt-Weber, Adam M. Chaker
Publikováno v: EBioMedicine, Vol 36, Iss , Pp 475-488 (2018)
Background: Allergen-specific immunotherapy (AIT) is a causative treatment in allergic airway disease, comprising long-term allergen administration and requiring three years of treatment. Mechanisms and biomarkers that translate into clinical efficac
Externí odkaz: https://doaj.org/article/8745664df04b40409aa0082b5e9a8c7a
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8
Flow-Based CL-SMIA for the Quantification of Protein Biomarkers from Nasal Secretions in Comparison with Sandwich ELISA
Autor: Seidel, Julia Neumair, Marie Kröger, Evamaria Stütz, Claudia Jerin, Adam M. Chaker, Carsten B. Schmidt-Weber, Michael
Publikováno v: Biosensors; Volume 13; Issue 7; Pages: 670
Protein biomarkers in nasal secretions can be used as a measure to differentiate between allergies, airway diseases and infections for non-invasive diagnostics. The point-of-care quantification of biomarker levels using flow-based microarray facilita
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::6a3bfb7bf24ccc7a5fb5b5e4ba30da48
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