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pro vyhledávání: '"Adam M, Bush"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/30822a6a726c476bbdfe194fb9c5a3c7
Autor:
Soyoung Choi, Adam M. Bush, Matthew T. Borzage, Anand A. Joshi, William J. Mack, Thomas D. Coates, Richard M. Leahy, John C. Wood
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 239-246 (2017)
Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic systemic and cerebral vascular disease that leads to early and cumulative neurological damage. Few studies have quantified the effects of this disease on
Externí odkaz:
https://doaj.org/article/eeed11f781c9458f95cdf848ac6af04e
Autor:
Adam M, Bush, Christopher M, Sandino, Shreya, Ramachandran, Frank, Ong, Nicholas, Dwork, Evan J, Zucker, Ali B, Syed, John M, Pauly, Marcus T, Alley, Shreyas S, Vasanawala
Publikováno v:
J Magn Reson Imaging
BACKGROUND: Quantitative T2* MRI is the standard of care for the assessment of iron overload. However, patient motion corrupts T2* estimates. PURPOSE: To develop and evaluate a motion robust, simultaneous cardiac and liver T2* imaging approach using
Publikováno v:
Magnetic resonance in medicine. 80(1)
TA Carr Purcell Meiboom Gill TEx vivo, SCD blood had greater saturation dependent relaxivity than control blood, with a weak dependence on HbS and no dependence on hematocrit. In vivo, the HbS TCerebral and peripheral oxygen extraction are decreased
Publikováno v:
Blood. 122:2210-2210
Neurovascular sequalae are a common occurrence in Sickle Cell Anemia (SCA), with 11% of patients suffering cerebral vascular accident (CVA), or overt stroke by their twentieth birthday and 40% of patients developing silent cerebral infarcts (SCI) by