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of 9
pro vyhledávání: '"Adam Lesiak"'
Autor:
Adam Lesiak, Carl Pelz, Hideaki Ando, Mingyan Zhu, Monika Davare, Talley J Lambert, Katelin F Hansen, Karl Obrietan, Suzanne M Appleyard, Soren Impey, Gary A Wayman
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64658 (2013)
Neurotrophin-regulated gene expression is believed to play a key role in long-term changes in synaptic structure and the formation of dendritic spines. Brain-derived neurotrophic factor (BDNF) has been shown to induce increases in dendritic spine for
Externí odkaz:
https://doaj.org/article/a3c8cf67529047d79eb49e6cf3031e8d
Autor:
Adam Lesiak, Dongren Yang, Donald A. Bruun, Pamela J. Lein, Diptiman D. Bose, Isaac N. Pessah, Gary A. Wayman, Veronica Ledoux
Publikováno v:
Environmental Health Perspectives
Background: Aroclor 1254 (A1254) interferes with normal dendritic growth and plasticity in the developing rodent brain, but the mechanism(s) mediating this effect have yet to be established. Non-dioxin-like (NDL) polychlorinated biphenyls (PCBs) enha
Autor:
Woo Yang Kim, Abby J. Engebose, Adam Lesiak, Robert Bucelli, Dennis Higgins, Gary A. Wayman, Monika A. Davare, Eugene A. Gonsiorek, Holly M. Lauridsen, Donald A. Bruun, Pamela J. Lein, Chris Barnhart
Publikováno v:
Journal of Neurochemistry. 108:1057-1071
Clinical and experimental evidence suggest that statins decrease sympathetic activity, but whether peripheral mechanisms involving direct actions on post-ganglionic sympathetic neurons contribute to this effect is not known. Because tonic activity of
Autor:
Mingyan Zhu, Gary A. Wayman, Adam Lesiak, Suzanne M. Appleyard, Hao Chen, Pamela J. Lein, Soren Impey
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 34, iss 3
Lesiak, Adam; Zhu, Mingyan; Chen, Hao; Appleyard, Suzanne M; Impey, Soren; Lein, Pamela J; et al.(2014). The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 717-725. doi: 10.1523/JNEUROSCI.2884-13.2014. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9gr02062
Lesiak, Adam; Zhu, Mingyan; Chen, Hao; Appleyard, Suzanne M; Impey, Soren; Lein, Pamela J; et al.(2014). The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 717-725. doi: 10.1523/JNEUROSCI.2884-13.2014. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9gr02062
Non–dioxin-like (NDL) polychlorinated biphenyls (PCBs) are widespread environmental contaminants linked to neuropsychological dysfunction in children. NDL PCBs increase spontaneous Ca2+oscillations in neurons by stabilizing ryanodine receptor (RyR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f823ed2e501fdf990722d15d778c42c
https://escholarship.org/uc/item/9gr02062
https://escholarship.org/uc/item/9gr02062
Autor:
Gary A. Wayman, Adam Lesiak, Diptiman D. Bose, Dongren Yang, Donald A. Bruun, Isaac N. Pessah, Pamela J. Lein, Soren Impey, Veronica Ledoux
Publikováno v:
Environmental Health Perspectives
Background: Non-dioxin-like (NDL) polychlorinated biphenyls (PCBs) promote dendritic growth in hippocampal neurons via ryanodine receptor (RyR)-dependent mechanisms; however, downstream signaling events that link enhanced RyR activity to dendritic gr
Autor:
Soren, Impey, Monika, Davare, Adam, Lesiak, Adam, Lasiek, Dale, Fortin, Hideaki, Ando, Olga, Varlamova, Karl, Obrietan, Thomas R, Soderling, Richard H, Goodman, Gary A, Wayman
Publikováno v:
Molecular and cellular neurosciences. 43(1)
Activity-regulated gene expression is believed to play a key role in the development and refinement of neuronal circuitry. Nevertheless, the transcriptional networks that regulate synaptic plasticity remain largely uncharacterized. We show here that
Autor:
Talley J. Lambert, Monika A. Davare, Suzanne M. Appleyard, Carl Pelz, Karl Obrietan, Mingyan Zhu, Gary A. Wayman, Soren Impey, Hideaki Ando, Katelin F. Hansen, Adam Lesiak
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64658 (2013)
PLoS ONE
PLoS ONE
Neurotrophin-regulated gene expression is believed to play a key role in long-term changes in synaptic structure and the formation of dendritic spines. Brain-derived neurotrophic factor (BDNF) has been shown to induce increases in dendritic spine for
Autor:
Soren Impey, Karl Obrietan, Richard H. Goodman, Monika A. Davare, Hideaki Ando, Thomas R. Soderling, Dale A. Fortin, Gary A. Wayman, Olga Varlamova, Adam Lesiak
Publikováno v:
Molecular and Cellular Neuroscience. 49:250
a Oregon Stem Cell Center, Oregon Health and Science University, Portland, OR, USA b Cell and Developmental Biology, Oregon Health and Science University, Portland, OR, USA c Department of Veterinary and Comparative Anatomy, Pharmacology and Physiolo
Publikováno v:
Philosophy, Ethics, and Humanities in Medicine, Vol 2, Iss 1, p 32 (2007)
Philosophy, ethics, and humanities in medicine : PEHM
Philosophy, ethics, and humanities in medicine : PEHM
Recent neuroscientific evidence brings into question the conclusion that all aspects of consciousness are gone in patients who have descended into a persistent vegetative state (PVS). Here we summarize the evidence from human brain imaging as well as