Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Adam Lacy‐Hulbert"'
Autor:
Lauren E. Vandepas, Caroline Stefani, Phillip P. Domeier, Nikki Traylor-Knowles, Frederick W. Goetz, William E. Browne, Adam Lacy-Hulbert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The formation of extracellular DNA traps (ETosis) is a first response mechanism by specific immune cells following exposure to microbes. Initially characterized in vertebrate neutrophils, cells capable of ETosis have been discovered recently
Externí odkaz:
https://doaj.org/article/70abc2b98b004544bd0053d2093f7627
Autor:
Zhangyu Cheng, Caroline Stefani, Thomas Skillman, Aleksandra Klimas, Aramchan Lee, Emma F. DiBernardo, Karina Mueller Brown, Tatyana Milman, Yuhong Wang, Brendan R. Gallagher, Katherine Lagree, Bhanu P. Jena, Jose S. Pulido, Scott G. Filler, Aaron P. Mitchell, N. Luisa Hiller, Adam Lacy‐Hulbert, Yongxin Zhao
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Super‐resolution optical imaging tools are crucial in microbiology to understand the complex structures and behavior of microorganisms such as bacteria, fungi, and viruses. However, the capabilities of these tools, particularly when it com
Externí odkaz:
https://doaj.org/article/f62ce5c239f04a70b2f59e74b0c6f6b3
Autor:
Abigail C. Dieter, Aliyah B. K. True, Emily A. Gilbertson, Grace Snyder, Adam Lacy-Hulbert, Nikki Traylor-Knowles, William E. Browne, Lauren E. Vandepas
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Cell suspension fluidics, such as flow cytometry (FCS) and fluorescence-activated cell sorting (FACS), facilitates the identification and precise separation of individual cells based on phenotype. Since its introduction, flow cytometry has been used
Externí odkaz:
https://doaj.org/article/0c509da849724eb797db7f32b0b8c129
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0232307 (2020)
In the mammalian gut CD103+ve myeloid DCs are known to suppress inflammation threatened by luminal bacteria, but stimuli driving DC precursor maturation towards this beneficial phenotype are incompletely understood. We isolated CD11+ve DCs from mesen
Externí odkaz:
https://doaj.org/article/97d75229ee644dadb10d1fbca164e204
Autor:
Satish Khurana, Sarah Schouteden, Javed K. Manesia, Albert Santamaria-Martínez, Joerg Huelsken, Adam Lacy-Hulbert, Catherine M. Verfaillie
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Integrins regulate haematopoietic stem cell (HSC) homeostasis and engraftment into the bone marrow (BM) niche upon transplantation. Here, the authors show that HSC quiescence and function in the BM is regulated by the interaction of PERIOSTIN and INT
Externí odkaz:
https://doaj.org/article/581340b96b30494088f56d7eb294bd30
Autor:
Fang Du, Abhishek V. Garg, Karis Kosar, Saikat Majumder, David G. Kugler, Gerard Hernandez Mir, Maria Maggio, Matthew Henkel, Adam Lacy-Hulbert, Mandy J. McGeachy
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1339-1351 (2016)
Interleukin-23 (IL-23) is required for inflammatory Th17 cell function in experimental autoimmune encephalomyelitis (EAE), and IL-23 blockade reduces the number of effector Th17 cells in the CNS. We report that pro-inflammatory Th17 cells express hig
Externí odkaz:
https://doaj.org/article/324f885d466240b7a5430ddae16ffdb0
Autor:
Mridu Acharya, Anna Sokolovska, Jenny M. Tam, Kara L. Conway, Caroline Stefani, Fiona Raso, Subhankar Mukhopadhyay, Marianela Feliu, Elahna Paul, John Savill, Richard O. Hynes, Ramnik J. Xavier, Jatin M. Vyas, Lynda M. Stuart, Adam Lacy-Hulbert
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-m
Externí odkaz:
https://doaj.org/article/dc8efeea8b80409f8e4a56aef9dd4da0
Autor:
Jenny M. Tam, Michael K. Mansour, Mridu Acharya, Anna Sokolovska, Allison K. Timmons, Adam Lacy-Hulbert, Jatin M. Vyas
Publikováno v:
Pathogens, Vol 5, Iss 2, p 34 (2016)
Autophagy plays an important role in maintaining cell homeostasis by providing nutrients during periods of starvation and removing damaged organelles from the cytoplasm. A marker in the autophagic process is the reversible conjugation of LC3, a membr
Externí odkaz:
https://doaj.org/article/feb0cb380d4042b3817d1946dd136180
Autor:
Lyly G Luhachack, Orane Visvikis, Amanda C Wollenberg, Adam Lacy-Hulbert, Lynda M Stuart, Javier E Irazoqui
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002798 (2012)
Understanding host defense against microbes is key to developing new and more effective therapies for infection and inflammatory disease. However, how animals integrate multiple environmental signals and discriminate between different pathogens to mo
Externí odkaz:
https://doaj.org/article/f086950cbd784a35afe744de2f788c99
Autor:
Nanda Kumar N Shanmugam, Shiri Ellenbogen, Estela Trebicka, Lijian Wang, Subhankar Mukhopadhyay, Adam Lacy-Hulbert, Carey Ann Gallini, Wendy S Garrett, Bobby J Cherayil
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38136 (2012)
Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control
Externí odkaz:
https://doaj.org/article/9defec2c10fa44c791073893257377ba