Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adam Kraya"'
Autor:
Nastaran Khalili, Anahita Fathi Kazerooni, Ariana Familiar, Debanjan Haldar, Adam Kraya, Jessica Foster, Mateusz Koptyra, Phillip B. Storm, Adam C. Resnick, Ali Nabavizadeh
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Increasing evidence suggests that besides mutational and molecular alterations, the immune component of the tumor microenvironment also substantially impacts tumor behavior and complicates treatment response, particularly to immunotherapies.
Externí odkaz:
https://doaj.org/article/ebcb81a7ea3240a59edeb9b5a3dbbbe6
Autor:
Sabine Mueller, Javad Nazarian, Sebastian M. Waszak, Adam Resnick, Michael Prados, Annette Molinaro, Michael Berens, Sara Byron, Winnie Liang, John Kuhn, Adam Kraya, Jo Lynne Rokita, Krutika S. Gaonkar, Bo Zhang, Sridevi Yadavilli, Jie Zhang, Madhuri Kambhampati, Yalan Zhang, Tracy Luks, Javier Villanueva-Meyer, Roger J. Packer, Anu Banerjee, John R. Crawford, Nalin Gupta, Erin R. Bonner, Lindsay Kilburn, Payal Jain, Cassie Kline
Purpose:PNOC003 is a multicenter precision medicine trial for children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG).Patients and Methods:Patients (3–25 years) were enrolled on the basis of imaging consistent with DI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd015a3199b4df3ee68f96b784b3d48
https://doi.org/10.1158/1078-0432.c.6532295
https://doi.org/10.1158/1078-0432.c.6532295
Autor:
Sabine Mueller, Javad Nazarian, Sebastian M. Waszak, Adam Resnick, Michael Prados, Annette Molinaro, Michael Berens, Sara Byron, Winnie Liang, John Kuhn, Adam Kraya, Jo Lynne Rokita, Krutika S. Gaonkar, Bo Zhang, Sridevi Yadavilli, Jie Zhang, Madhuri Kambhampati, Yalan Zhang, Tracy Luks, Javier Villanueva-Meyer, Roger J. Packer, Anu Banerjee, John R. Crawford, Nalin Gupta, Erin R. Bonner, Lindsay Kilburn, Payal Jain, Cassie Kline
Supplementary Figure from Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019d2fe800b2e02f3568ddd329dc848f
https://doi.org/10.1158/1078-0432.22486334.v1
https://doi.org/10.1158/1078-0432.22486334.v1
Autor:
Mateusz P. Koptyra, Komal Rahti, Yuankun Zhu, Bailey Farrow, Daniel Miller, Adam Kraya, Yiran Guo, Peter Madsen, Nicholas Van Kuren, Xiaoyan Huang, Miguel A. Brown, Jennifer L. Mason, Meen Chul Kim, Allison P. Heath, Brian M. Ennis, Bo Zhang, Jena V. Lilly, Jo Lynne Rokita, Christopher Friedman, Ximena P. Cuellar, Catherine A. Sullivan, Noel Coleman, Trang Duros, Thinh Q. Nguyen, Emmett C. Drake, Zeinab Helili, Beth A. Frenkel, Gerri R. Trooskin, Ariana Familiar, Karthik Viswanathan, Christopher M. Beck, Madison L. Hollawell, Valerie P. Baubet, Cassie Kline, Mariarita Santi, Tatiana S. Patton, Stephanie Stefankiewicz, Arya Kamnaa, Ryan A. Velasco, Dani Cardona, Phillip J. Storm, Adam C. Resnick, o/b/o Children's Brain Tumor Network
Publikováno v:
Cancer Research. 83:3566-3566
Pediatric central nervous system (CNS) cancers are the leading disease-related cause of death in children and there is urgent need for curative therapeutic strategies for these tumors. To address the urgency, Children’s Brain Tumor Network (CBTN) h
Autor:
Cassie Kline, Payal Jain, Lindsay Kilburn, Erin R. Bonner, Nalin Gupta, John R. Crawford, Anu Banerjee, Roger J. Packer, Javier Villanueva-Meyer, Tracy Luks, Yalan Zhang, Madhuri Kambhampati, Jie Zhang, Sridevi Yadavilli, Bo Zhang, Krutika S. Gaonkar, Jo Lynne Rokita, Adam Kraya, John Kuhn, Winnie Liang, Sara Byron, Michael Berens, Annette Molinaro, Michael Prados, Adam Resnick, Sebastian M. Waszak, Javad Nazarian, Sabine Mueller
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 18
Purpose: PNOC003 is a multicenter precision medicine trial for children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG). Patients and Methods: Patients (3–25 years) were enrolled on the basis of imaging consistent with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a9b835658a9d0d6b17be3ef0fc3563
http://hdl.handle.net/10852/99343
http://hdl.handle.net/10852/99343
Autor:
Ammar Naqvi, Brian Ennis, Run Jin, Krutika Gaonkar, Jessica Foster, Karina Conkrite, Komal Rathi, Adam Kraya, Poonam Sonawane, Peter Madsen, Phillip Storm, Adam Resnick, Jo Lynne Rokita
Publikováno v:
Neuro-Oncology. 24:i74-i74
While much of the somatic coding variation underlying the oncogenic transformation of pediatric high-grade gliomas (HGGs) has been profiled, transcriptional splicing programs of these tumors remain under-explored. Here, we characterize aberrant alter
Autor:
Cassie Kline, Payal Jain, Lindsay Kilburn, Erin Bonner, Nalin Gupta, John Crawford, Anu Banerjee, Roger Packer, Javier Villanueva-Meyer, Tracy Luks, Yalan Zhang, Madhuri Kambhampati, Jie Zhang, Sridevi Yadavilli, Adam Kraya, John Kuhn, Winnie Liang, Sara Byron, Michael Berens, Annette Molinaro, Michael Prados, Adam Resnick, Sebastian Waszak, Javad Nazarian, Sabine Mueller
Publikováno v:
Neuro-Oncology. 24:i25-i25
BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a fatal brain tumor. Herein, we report on novel prognostic and predictive genomic biomarkers identified in PNOC003, a multi-center precision medicine trial for children and young adults diagnosed
Autor:
Adam Kraya, Run Jin, Chao Zhao, Ariana Familiar, Kathryn Wellen, Adam Resnick, Ali Nabavizadeh
Publikováno v:
Neuro-Oncology. 24:i185-i185
Glutamine transporters play an important role in supporting increased tumor nutritional demands relative to non-cancerous cells, often through overexpression of the solute carrier (SLC) family of membrane transporters. Preclinical studies in adult ca