Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Adam Kramer"'
Autor:
Yan-Ruide Li, Christopher J. Ochoa, Yichen Zhu, Adam Kramer, Matthew Wilson, Ying Fang, Yuning Chen, Tanya Singh, Gabriella Di Bernardo, Enbo Zhu, Derek Lee, Neda A. Moatamed, Joanne Bando, Jin J. Zhou, Sanaz Memarzadeh, Lili Yang
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107952- (2023)
Summary: Ovarian cancer (OC) is highly lethal due to late detection and frequent recurrence. Initial treatments, comprising surgery and chemotherapy, lead to disease remission but are invariably associated with subsequent relapse. The identification
Externí odkaz:
https://doaj.org/article/e68f8f2be25746a2bb19bb49db0b3901
Autor:
Adam Kramer, E. Rickamer Hoover, Nicole Hedeen, Lauren DiPrete, Joyce Tuttle, DJ Irving, Brendalee Viveiros, David Nicholas, Jo Ann Monroy, Erin Moritz, Laura Brown
Publikováno v:
Journal of Food Protection, Vol 86, Iss 3, Pp 100043- (2023)
A poor food safety culture has been described as an emerging risk factor for foodborne illness outbreaks, yet there has been little research on this topic in the retail food industry. The purpose of this study was to identify and validate conceptual
Externí odkaz:
https://doaj.org/article/a2c826804d1b4a18bdf10444b3f393a7
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
The realm of cell-based immunotherapy holds untapped potential for the development of next-generation cancer treatment through genetic engineering of chimeric antigen receptor (CAR)-engineered T (CAR-T) cell therapies for targeted eradication of canc
Externí odkaz:
https://doaj.org/article/12ed59c48b6843dfb707207bfd8432de
Autor:
Yan-Ruide Li, Samuel Zeng, Zachary Spencer Dunn, Yang Zhou, Zhe Li, Jiaji Yu, Yu-Chen Wang, Josh Ku, Noah Cook, Adam Kramer, Lili Yang
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104859- (2022)
Summary: Allo-HSCT is a curative therapy for hematologic malignancies owing to GvL effect mediated by alloreactive T cells; however, the same T cells also mediate GvHD, a severe side effect limiting the widespread application of allo-HSCT in clinics.
Externí odkaz:
https://doaj.org/article/4e0a41e2b4ef489a972d6c4d8016a3bc
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4084 (2023)
Allogeneic cell therapies, defined by genetically mismatched transplantation, have the potential to become a cost-effective solution for cell-based cancer immunotherapy. However, this type of therapy is often accompanied by the development of graft-v
Externí odkaz:
https://doaj.org/article/11dac6f947ec4a4f9be680b87e756e82
Autor:
Junran J. Peng, Navid Saleh, Thomas M. Roston, Adam Kramer, Lubomira Cermakova, G.B. John Mancini, Christopher B. Fordyce, Liam R. Brunham
Publikováno v:
American Heart Journal Plus, Vol 13, Iss , Pp 100097- (2022)
Familial hypercholesterolemia (FH) is an inherited condition characterized by elevated low-density lipoprotein cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular disease (ASCVD). Despite being the most common inherited cardiovasc
Externí odkaz:
https://doaj.org/article/065e74ac3374496bbbb3ff34f2903f99
Autor:
Yan-Ruide Li, Yang Zhou, Matthew Wilson, Adam Kramer, Ryan Hon, Yichen Zhu, Ying Fang, Lili Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7547 (2022)
Invariant natural killer T (iNKT) cells have the capacity to mount potent anti-tumor reactivity and have therefore become a focus in the development of cell-based immunotherapy. iNKT cells attack tumor cells using multiple mechanisms with a high effi
Externí odkaz:
https://doaj.org/article/b419192007394802812717559649a887
Autor:
Yan-Ruide Li, James Brown, Yanqi Yu, Derek Lee, Kuangyi Zhou, Zachary Spencer Dunn, Ryan Hon, Matthew Wilson, Adam Kramer, Yichen Zhu, Ying Fang, Lili Yang
Publikováno v:
Cancers, Vol 14, Iss 11, p 2749 (2022)
The field of T cell-based and chimeric antigen receptor (CAR)-engineered T (CAR-T) cell-based antitumor immunotherapy has seen substantial developments in the past decade; however, considerable issues, such as graft-versus-host disease (GvHD) and tum
Externí odkaz:
https://doaj.org/article/f8def09c21ca422cb07affc32d7e8bfa
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy
Publikováno v:
Cells, Vol 11, Iss 9, p 1583 (2022)
Tumor-associated macrophages (TAMs) accumulate in the solid tumor microenvironment (TME) and have been shown to promote tumor growth and dampen antitumor immune responses. TAM-mediated suppression of T-cell antitumor reactivity is considered to be a
Externí odkaz:
https://doaj.org/article/868aab000c1046e5b29fcd08f9535442