Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Adam Koebel"'
Autor:
Maneesha A Rajora, Marta Overchuk, Danielle M. Charron, Brian C. Wilson, Shrey Sindhwani, Warren C. W. Chan, Gang Zheng, Martin G. Pomper, Abdullah Muhammad Syed, Adam Koebel, Juan Chen, Kara M. Harmatys
Publikováno v:
Nano letters. 21(1)
Limited tumor nanoparticle accumulation remains one of the main challenges in cancer nanomedicine. Here, we demonstrate that subtherapeutic photodynamic priming (PDP) enhances the accumulation of nanoparticles in subcutaneous murine prostate tumors
Autor:
Shigeki Tsutsui, Andrew V. Caprariello, Vahid Hoghooghi, Megan L. Morgan, Jason R. Plemel, Adam Koebel, James A. Rogers, Peter K. Stys, Jeff F. Dunn, Shalina S. Ousman, Lakshmi P. Kotra, V. Wee Yong
Publikováno v:
Proceedings of the National Academy of Sciences. 115:5528-5533
Although immune attack against central nervous system (CNS) myelin is a central feature of multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct evidence that subtle biochemical modifications to brain myelin elicit
Autor:
Lakshmi P. Kotra, Ewa Wasilewski, Shannon E. Dunn, Angelica M. Bello, Elizabeth J. Curiel Tejeda, Adam Koebel
Publikováno v:
Journal of Medicinal Chemistry. 60:8876-8887
Peptidyl arginine deiminases have been shown to be hyperactive in neurodegenerative diseases including multiple sclerosis. An α-amino acid-based core structure, derived from a hydantoin core, with unique heterocycles on the side chains were synthesi