Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adam Klosin"'
Autor:
Jose A. Morin, Sina Wittmann, Sandeep Choubey, Adam Klosin, Stefan Golfier, Anthony A. Hyman, Frank Jülicher, Stephan W. Grill
Publikováno v:
Nature Physics. 18:271-276
Biomolecular condensates are dense assemblies of proteins that form distinct biochemical compartments without being surrounded by a membrane. Some, such as P granules and stress granules, behave as droplets and contain many millions of molecules. Oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494916000130a6bb0bba3e5873a5de8b
https://doi.org/10.1038/s41567-021-01462-2
https://doi.org/10.1038/s41567-021-01462-2
Autor:
Adam Klosin, Tyler S. Harmon, F Oltsch, Anthony A. Hyman, Alf Honigmann, Frank Jülicher, Christoph Zechner
Publikováno v:
Science
Keeping the noise down Protein concentrations in a cell fluctuate considerably because of stochasticity in gene expression and variations in the cell's microenvironment. How cells cope with concentration fluctuations when precision is important is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aced5553dffca217c646d6f9fb65373
https://doi.org/10.1126/science.aav6691
https://doi.org/10.1126/science.aav6691
Autor:
Anthony A. Hyman, Adam Klosin, Frank Jülicher, Sina Wittmann, Stefan Golfier, Sandeep Choubey, Jose A. Morin, Stephan W. Grill
In the last decade, extensive studies on the properties of non-membrane-bound compartments in the cellular cytoplasm have shown that concepts in phase separation drawn from physical chemistry can describe their formation and behaviour1–4. Current e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1477d1c1ad9c7bc487446f7daffa5e25
https://doi.org/10.1101/2020.09.24.311712
https://doi.org/10.1101/2020.09.24.311712
A central problem in cellular control is how cells cope with the inherent noise in gene expression. Although transcriptional and posttranscriptional feedback mechanisms can suppress noise, they are often slow, and cannot explain how cells buffer acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffd1ede3184e3a19db88973ac5f9daf9
https://doi.org/10.1101/524231
https://doi.org/10.1101/524231
Autor:
Kai Sundmacher, Ivan Ivanov, Anthony A. Hyman, Katharina Landfester, T-Y Dora Tang, Rumiana Dimova, Adam Klosin, Lucas Caire da Silva, Titus M. Franzmann, Reinhard Lipowsky, Rafael de Lira
Publikováno v:
Advanced Biosystems
Contemporary biological cells are sophisticated and highly compartmentalized. Compartmentalization is an essential principle of prebiotic life as well as a key feature in bottom-up synthetic biology research. In this review, the dynamic growth of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283573004d39699f33495241bd16561d
https://hdl.handle.net/21.11116/0000-0007-42ED-421.11116/0000-0003-0511-4
https://hdl.handle.net/21.11116/0000-0007-42ED-421.11116/0000-0003-0511-4
Publikováno v:
Science
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
The environment experienced by an animal can sometimes influence gene expression for one or a few subsequent generations. Here, we report the observation that a temperature-induced change in expression from a Caenorhabditis elegans heterochromatic ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7267c30547e00f991e11dfb5af859122
http://hdl.handle.net/10230/36780
http://hdl.handle.net/10230/36780
Publikováno v:
Science Advances
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Inhibiting DNA replication in C. elegans embryos causes loss of repressive histone modifications and generates epialleles.
Impaired DNA replication is a hallmark of cancer and a cause of genomic instability. We report that, in addition to causin
Impaired DNA replication is a hallmark of cancer and a cause of genomic instability. We report that, in addition to causin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4dbf889ab9f61129165f090e5bcf0d
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6148
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6148
Publikováno v:
Science (New York, N.Y.). 356(6335)
The environment experienced by an animal can sometimes influence gene expression for one or a few subsequent generations. Here, we report the observation that a temperature-induced change in expression from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5187c2f7869177b5d173403990514e77
https://pubmed.ncbi.nlm.nih.gov/28428426
https://pubmed.ncbi.nlm.nih.gov/28428426
Autor:
Adam Klosin, Anthony A. Hyman
Publikováno v:
Nature. 547:168-169
The protein HP1 mediates compaction of DNA into a repressive structure called heterochromatin. Analysis reveals that HP1 has liquid-like properties, offering a fresh perspective on genome organization. See Letters p.236 & p.241 The gene-silencing act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a854ddedc8b92c1d5e986745424d4395
https://doi.org/10.1038/nature23089
https://doi.org/10.1038/nature23089
Autor:
Daniel J. Müller, Adam Klosin, Alexej Kedrov, Alex M. Hellawell, R. Bill Broadhurst, Edmund R.S. Kunji
Publikováno v:
Structure. 18:39-46
Mitochondrial ADP/ATP carriers are inhibited by two natural compounds, atractyloside (ATR) or carboxy-atractyloside (CATR), which differ by one carboxylate group. The interactions of the inhibitors with the carrier were investigated by single-molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d696559ce63b12e1be556b0f05fbb39
https://doi.org/10.1016/j.str.2009.11.009
https://doi.org/10.1016/j.str.2009.11.009