Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adam Keeton"'
Autor:
Md Yeashin Gazi, Ogacheko Okoko, Xin Wang, Caitlin Brandle, Zhi-chun Ding, Amit Mitra, Veronica Ramirez-Alcantara, Xi Chen, Adam Keeton, Yulia Maxuitenko, Gary Piazza, Gang Zhou
Publikováno v:
Cancer Research. 83:478-478
Previous research suggests that the antineoplastic activity of sulindac is mediated by a cyclooxygenase (COX) independent mechanism involving dual inhibition of RAS and β-catenin signaling. ADT030 is a novel non-COX inhibitory sulindac-derivative de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c556ee24e963d3c812b1826dc538459
https://doi.org/10.1158/1538-7445.am2023-478
https://doi.org/10.1158/1538-7445.am2023-478
Autor:
Md Yeashin Gazi, Caitlin Brandle, Ogacheko Okoko, Xi Chen, Adam Keeton, Yulia Maxuitenko, Gary Piazza, Gang Zhou
Publikováno v:
Cancer Research. 82:5322-5322
Phosphodiesterase 10 (PDE10) is overexpressed in several types of cancer, including lung, breast and colon cancers. It has been proposed that inhibitors targeting PDE10 may exhibit antitumor activities. Previous studies have shown that PDE10 inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fad75682bae5a3733ba157778bb64404
https://doi.org/10.1158/1538-7445.am2022-5322
https://doi.org/10.1158/1538-7445.am2022-5322
Autor:
Mohamed Salah, Rezk, Mohammad, Abdel-Halim, Adam, Keeton, Derek, Franklin, Matthias, Bauer, Frank Michael, Boeckler, Matthias, Engel, Rolf Wolfgang, Hartmann, Yanping, Zhang, Gary Anthony, Piazza, Ashraf Hassan, Abadi
Publikováno v:
Chemicalpharmaceutical bulletin. 64(1)
Twelve derivatives of the general formula 3-substituted-6-chloroindoles were synthesized and tested for their growth inhibitory effects versus p53(+/+) colorectal cancer HCT116 and its p53 knockout isogenic cells; colorectal cancer cell p53(-/-) SW48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11f1d7ef54d3a8e467065048ce03b97e
https://pubmed.ncbi.nlm.nih.gov/26726742
https://pubmed.ncbi.nlm.nih.gov/26726742
Publikováno v:
Endocrine (1355008X); Oct2007, Vol. 32 Issue 2, p219-226, 8p