Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Adam Kassan"'
Autor:
Undral Munkhsaikhan, Young In Kwon, Amal M. Sahyoun, María Galán, Alexis A. Gonzalez, Karima Ait-Aissa, Ammaar H. Abidi, Adam Kassan, Modar Kassan
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1287 (2023)
Objectives: Homozygous familial hypercholesteremia (HoFH) is a rare, life-threatening metabolic disease, mainly caused by a mutation in the LDL receptor. If untreated, HoFH causes premature death from acute coronary syndrome. Lomitapide is approved b
Externí odkaz:
https://doaj.org/article/a7c38969a08a46858fe0bd9ead16100e
Autor:
Karima Ait-Aissa, Quynh My Nguyen, Mohanad Gabani, Adam Kassan, Santosh Kumar, Soo-Kyoung Choi, Alexis A. Gonzalez, Tahsin Khataei, Amal M. Sahyoun, Cheng Chen, Modar Kassan
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-26 (2020)
Abstract The endothelium plays a pivotal role in maintaining vascular health. Obesity is a global epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity perturbs the integrity of normal endothelium, leading to endo
Externí odkaz:
https://doaj.org/article/e41916ad23f04d7ab421d60fe1fd4f6c
Autor:
Modar Kassan, Youngin Kwon, Undral Munkhsaikhan, Amal M. Sahyoun, Tauheed Ishrat, María Galán, Alexis A. Gonzalez, Ammaar H. Abidi, Adam Kassan, Karima Ait-Aissa
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 160 (2023)
Objectives: Short-chain fatty acids (SCFAs), the main metabolites released from the gut microbiota, are altered during hypertension and obesity. SCFAs play a beneficial role in the cardiovascular system. However, the effect of SCFAs on cerebrovascula
Externí odkaz:
https://doaj.org/article/729830134052436ea959c4694693e885
Autor:
Kassan, Undral Munkhsaikhan, Young In Kwon, Amal M. Sahyoun, María Galán, Alexis A. Gonzalez, Karima Ait-Aissa, Ammaar H. Abidi, Adam Kassan, Modar
Publikováno v:
Antioxidants; Volume 12; Issue 6; Pages: 1287
Objectives: Homozygous familial hypercholesteremia (HoFH) is a rare, life-threatening metabolic disease, mainly caused by a mutation in the LDL receptor. If untreated, HoFH causes premature death from acute coronary syndrome. Lomitapide is approved b
Publikováno v:
Physiology. 38
Objectives: Short chain fatty acids (SCFAs), the main metabolites released from the gut microbiota, are reduced during hypertension. SCFAs play a beneficial role on the cardiovascular system. However, the effect of SCFAs on cerebrovascular endothelia
Autor:
Undral Munkhsaikhan, Youngin Kwon, Amal M. Sahyoun, Karima Ait‐Aissa, Adam Kassan, Modar Kassan
Publikováno v:
Obesity (Silver Spring)
OBJECTIVES: In this study, we investigate the effect of lomitapide, a microsomal triglyceride transfer protein inhibitor, on the cardiovascular function in obesity. METHODS: Eight-week-old C57BL/6 mice were fed with high fat diet (HFD) for 12 weeks i
Autor:
Undral Munkhsaikhan, Young‐In Kwon, Amal M. Sahyoun, Karima Ait‐Aissa, Modar Kassan, Adam Kassan
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Cureus.
The prevalence of obesity is increasing worldwide, and novel therapeutic strategies such as enhancement of thermogenic pathways in white adipose tissue (WAT) are gaining more attention. The gut/brain axis plays an essential role in promoting the brow
Publikováno v:
Cureus
There is abundant evidence demonstrating the association between gut dysbiosis and neurogenic diseases such as hypertension. A common characteristic of resistant hypertension is the chronic elevation in sympathetic nervous system (SNS) activity accom
Association of Cardiotoxicity With Doxorubicin and Trastuzumab: A Double-Edged Sword in Chemotherapy
Autor:
Mohanad, Gabani, Diana, Castañeda, Quynh My, Nguyen, Soo-Kyoung, Choi, Cheng, Chen, Ayesha, Mapara, Adam, Kassan, Alexis A, Gonzalez, Tahsin, Khataei, Karima, Ait-Aissa, Modar, Kassan
Publikováno v:
Cureus
Anticancer drugs play an important role in reducing mortality rates and increasing life expectancy in cancer patients. Treatments include monotherapy and/or a combination of radiation therapy, chemotherapy, hormone therapy, or immunotherapy. Despite