Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Adam K. Wade-Vallance"'
Publikováno v:
Curr Opin Immunol
Stringent regulation of IgE antibody production is critical for constraining allergic responses. This review discusses recent advances in understanding cell-intrinsic and extrinsic mechanisms that regulate the genesis and fate of IgE B cells. B cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3241d81b569eb36f40ab6d7486c8bce
https://doi.org/10.1016/j.coi.2021.06.005
https://doi.org/10.1016/j.coi.2021.06.005
Autor:
Robin Kageyama, Simon K. Zhou, Daisuke Kitamura, Adam J. Litterman, John J. O'Shea, Eric J. Wigton, Christopher D.C. Allen, Adam K. Wade-Vallance, Carlos A. Castellanos, Suparna Roy, K. Mark Ansel, Yohei Mikami, Ryan J. McMonigle, Emily C. Dykhuizen, Hui Hu
Publikováno v:
Journal of Experimental Medicine. 218
MicroRNAs (miRNAs, miRs) regulate cell fate decisions by post-transcriptionally tuning networks of mRNA targets. We used miRNA-directed pathway discovery to reveal a regulatory circuit that influences Ig class switch recombination (CSR). We developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be428cfdaad2618aeaa4d2914cc9876
https://doi.org/10.1084/jem.20201422
https://doi.org/10.1084/jem.20201422
Autor:
Adam K Wade-Vallance, Chi Kin Wong, Francis C. Lynn, Dan S. Luciani, Paul K. Brindle, William T. Gibson
Publikováno v:
Diabetes. 67(3)
p300 (EP300) and CBP (CREBBP) are transcriptional coactivators with histone acetyltransferase activity. Various β-cell transcription factors can recruit p300/CBP, and thus the coactivators could be important for β-cell function and health in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2044c69f55ba32418c45899921e669
https://pubmed.ncbi.nlm.nih.gov/29217654
https://pubmed.ncbi.nlm.nih.gov/29217654