Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adam Jassowicz"'
Autor:
Anna-Lena Scherr, Henning Schulze-Bergkamen, Benjamin Goeppert, Nathalie Schmitt, Adam Jassowicz, Georg Gdynia, Anna Pató, Bruno Köhler, Dirk Jäger, Lars Ismail, Lasse Neukirch, Paula Hoffmeister, Christin Elssner
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1099 (2020)
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1099 (2020)
Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferat
Autor:
Henning Schulze-Bergkamen, Georg Gdynia, Wilfried Roth, Martin Schneider, Mariam Salou, You-Wen He, Achim Weber, Praveen Radhakrishnan, Adam Jassowicz, Christin Elssner, Dirk Jaeger, Nicole Kautz, Bruno Christian Koehler, Sophia Keim, Katarina Duglova, Anette Heller, Mathias Heikenwalder, Anna Lena Scherr
Publikováno v:
Cell Death & Disease
Cell Death Dis. 7:e2342 (2016)
Cell Death Dis. 7:e2342 (2016)
Colorectal cancer (CRC) is the second most common malignant neoplasia in women and men worldwide. The B-cell lymphoma 2 (Bcl-2) protein family is mainly known for its pivotal role in the regulation of the mitochondrial death pathway. Anti-apoptotic B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3f61b83847b959e2a50e56ba9048f9
https://www.zora.uzh.ch/id/eprint/125660/
https://www.zora.uzh.ch/id/eprint/125660/
Publikováno v:
The Journal of pharmacy and pharmacology. 67(11)
Objectives Obatoclax is a pan-Bcl-2 inhibitor with promising efficacy, especially when combined with other antineoplastic agents. Pharmacokinetic drug–drug interactions can occur systemically and at the level of the tumour cell. Thus, this study sc
Autor:
Nicole Kautz, Henning Schulze-Bergkamen, Martin Schneider, Dirk Jaeger, Stephan Lorenz, Adam Jassowicz, Johanna Weiss, Bruno Christian Koehler, Praveen Radhakrishnan, Christin Elssner, Anna-Lena Scherr
Publikováno v:
BMC Cancer
Background Colorectal cancer is the third most common malignancy in humans and novel therapeutic approaches are urgently needed. Autophagy is an evolutionarily highly conserved cellular process by which cells collect unnecessary organelles or misfold