Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Adam J. Meyer"'
Autor:
Christopher A Vaiana, Hyungseok Kim, Jonathan Cottet, Keiko Oai, Zhifei Ge, Kameron Conforti, Andrew M King, Adam J Meyer, Haorong Chen, Christopher A Voigt, Cullen R Buie
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 3, Pp n/a-n/a (2022)
Abstract Living materials combine a material scaffold, that is often porous, with engineered cells that perform sensing, computing, and biosynthetic tasks. Designing such systems is difficult because little is known regarding signaling transport para
Externí odkaz:
https://doaj.org/article/b9a109db513546acac61a1ae10a3afc9
Autor:
Nathan D. Schwalm, Adam D. Silverman, Cassandra Bristol, Maneesh K. Gupta, Julius P. Lucks, Carrie A. Drake, Wendy J. Crookes-Goodson, Michael C. Jewett, Sarah M. Glaven, Steven M Blum, Nancy Kelley-Loughnane, Alexander V. Tobias, Raissa Eluere, Elizabeth L. Onderko, Wais Mojadedi, Felix Moser, Christopher A. Voigt, Matthew P. Lux, Arturo Casini, R. L. Mickol, Katelin Pratt, Katherine L. Akingbade, Vanessa A. Varaljay, D. Benjamin Gordon, Adam J. Meyer, Shangtao Liu, Ishtiaq Saaem
Publikováno v:
ACS Synthetic Biology. 8:2746-2755
Organism engineering requires the selection of an appropriate chassis, editing its genome, combining traits from different source species, and controlling genes with synthetic circuits. When a strain is needed for a new target objective, for example,
Autor:
Carly R. Muletz-Wolz, Brian Gratwicke, Christopher A. Voigt, Jennifer A N Brophy, Ed Bronikowski, Matthew H. Becker, Alyssa W. Kaganer, Robert C. Fleischer, Elliot Lassiter, Matthew Evans, Emerson Glassey, Blake Klocke, Kevin Barrett, Adam J. Meyer
Publikováno v:
ISME Communications. 1
We designed two probiotic treatments to control chytridiomycosis caused by Batrachochytrium dendrobatidis (Bd) on infected Panamanian golden frogs (Atelopus zeteki), a species that is thought to be extinct in the wild due to Bd. The first approach di
Publikováno v:
Nature chemical biology. 15(2)
Cellular processes are carried out by many genes, and their study and optimization requires multiple levers by which they can be independently controlled. The most common method is via a genetically encoded sensor that responds to a small molecule. H
Cellular processes are carried out by many interacting genes and their study and optimization requires multiple levers by which they can be independently controlled. The most common method is via a genetically-encoded sensor that responds to a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd1b81816beea6454a593ece103dc78
Autor:
Nilesh B. Karalkar, Hyo Joong Kim, Andrew D. Ellington, Myong Jung Kim, Steven A. Benner, Shuichi Hoshika, John SantaLucia, Norman E. Watkins, Joseph A. Piccirilli, Alison M. Bates, Nicole A. Leal, Holly A. SantaLucia, Adam J. Meyer, Millie M. Georgiadis, Myong Sang Kim, Saurja DasGupta
Publikováno v:
Biochemistry
Steve Benner and collaborators have recently reported an analysis of DNA containing eight nucleotide letters – the four natural letters dG, dC, dA, and dT, and four additional letters, called dP, dZ, dS, and dB. Their analysis demonstrates that the
Publikováno v:
Chemical communications (Cambridge, England). 53(91)
Thermostable T7 RNA polymerase variants were explored for genetic alphabet expansion transcription involving the unnatural Ds–Pa pair. One variant exhibited high incorporation efficiencies of functionally modified Pa substrates and enabled the simu
Autor:
Michelle Byrom, Hannah G. McDonald, Y. Whitney Yin, Daniel J. Garry, Bradley Hall, Xu Yang, Andrew D. Ellington, Adam J. Meyer
Publikováno v:
Nucleic Acids Research
On average, mutations are deleterious to proteins. Mutations conferring new function to a protein often come at the expense of protein folding or stability, reducing overall activity. Over the years, a panel of T7 RNA polymerases have been designed o
Autor:
Laura Martini, Michele Forlin, Sheref S. Mansy, Jared W. Ellefson, Andrew D. Ellington, Adam J. Meyer, John N. Milligan
Publikováno v:
ACS Synthetic Biology. 4:1144-1150
An in vitro selection method for ligand-responsive RNA sensors was developed that exploited strand displacement reactions. The RNA library was based on the thiamine pyrophosphate (TPP) riboswitch, and RNA sequences capable of hybridizing to a target
Publikováno v:
ACS Synthetic Biology. 4:1070-1076
T7 RNA polymerase is the foundation of synthetic biological circuitry both in vivo and in vitro due to its robust and specific control of transcription from its cognate promoter. Here we present the directed evolution of a panel of orthogonal T7 RNA