Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adam J. Lopez-Denman"'
Publikováno v:
Viruses, Vol 9, Iss 1, p 14 (2017)
Flaviviruses are a large group of arboviruses of significant medical concern worldwide. With outbreaks a common occurrence, the need for efficient viral control is required more than ever. It is well understood that flaviviruses modulate the composit
Externí odkaz:
https://doaj.org/article/cf60ad818d1147f0b5ed98014a2ccf4b
Autor:
Peter A. White, Daniel Enosi Tuipulotu, Adam J. Lopez-Denman, Jessica B Ross, Alice M Trenerry, Jason M. Mackenzie
Publikováno v:
Virology. 559:131-144
The involvement of the nucleus during flavivirus infection has been observed in only a small number of cases and can be limited to primarily two viral proteins; the structural protein C and the RNA polymerase NS5. Previously we observed that by block
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Mosquito-borne diseases exert a huge impact on both animal and human populations, posing substantial health risks. The behavioural and fitness traits of mosquitoes, such as locomotion and fecundity, are crucial factors that influe
Externí odkaz:
https://doaj.org/article/9564463f21b14b7e9c510dee019ac708
Publikováno v:
Viruses, Vol 16, Iss 7, p 1134 (2024)
Mosquitoes of the Culex genus are responsible for a large burden of zoonotic virus transmission globally. Collectively, they play a significant role in the transmission of medically significant diseases such as Japanese encephalitis virus and West Ni
Externí odkaz:
https://doaj.org/article/e39fb4476d204f18b26590a49c0a8999
Autor:
Anthony D. Kelleher, Amy W. Chung, Stephen J. Kent, Adam J. Lopez-Denman, Matthew J. Worley, Kuangyu Fei
Publikováno v:
Journal of Immunological Methods. 457:41-52
There is growing evidence to support the role of Fc-mediated effector functions, such as Antibody-Dependent Cellular cytotoxicity (ADCC) and Antibody-Dependent Phagocytosis (ADP) in the protection and control of HIV. The RV144 trial and other recent
Autor:
Peter A. White, Adam J. Lopez-Denman, David A. Jans, Kylie M. Wagstaff, Jason M. Mackenzie, Alice G. Russo
Publikováno v:
Cellular microbiology. 20(8)
West Nile virus (WNV) is a single-stranded, positive sense RNA virus of the family Flaviviridae and is a significant pathogen of global medical importance. Flavivirus replication is known to be exclusively cytoplasmic, but we show here for the first
Publikováno v:
Viruses
Viruses, Vol 9, Iss 1, p 14 (2017)
Viruses, Vol 9, Iss 1, p 14 (2017)
Flaviviruses are a large group of arboviruses of significant medical concern worldwide. With outbreaks a common occurrence, the need for efficient viral control is required more than ever. It is well understood that flaviviruses modulate the composit
Autor:
Caroline A. Hick, David A. Jans, Kylie M. Wagstaff, Adam J. Lopez-Denman, Patrick M. Sexton, Satoru Watanabe, Subhash G. Vasudevan, Belinda Maher, Jason M. Mackenzie, Chunxiao Wang, Johanna E. Fraser, Wing K K Chan
Publikováno v:
The Journal of infectious diseases. 210(11)
Background Dengue virus (DENV) is estimated to cause 390 million infections each year, but there is no licensed vaccine or therapeutic currently available. Methods We describe a novel, high-throughput screen to identify compounds inhibiting the inter
Autor:
Susann Liebscher, Rebecca L Ambrose, Turgut E Aktepe, Andrea Mikulasova, Julia E Prier, Leah K Gillespie, Adam J Lopez-Denman, Thusitha W T Rupasinghe, Dedreia Tull, Malcolm J McConville, Jason M Mackenzie
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007029 (2018)
Positive-sense RNA virus intracellular replication is intimately associated with membrane platforms that are derived from host organelles and comprised of distinct lipid composition. For flaviviruses, such as West Nile virus strain Kunjin virus (WNVK
Externí odkaz:
https://doaj.org/article/8dd0692a726149698f1db45e8f5456da