Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Adam J. Gilbertsen"'
Autor:
Christian Martin, Kathleen S. Mahan, Talia D. Wiggen, Adam J. Gilbertsen, Marshall I. Hertz, Ryan C. Hunter, Robert A. Quinn
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Background Progression of chronic lung disease may lead to the requirement for lung transplant (LTx). Despite improvements in short-term survival after LTx, chronic lung allograft dysfunction (CLAD) remains a critical challenge for long-term
Externí odkaz:
https://doaj.org/article/f2779c4e36f2402580fa37a1dee2c5bf
Autor:
Christian Martin, Kathleen S. Mahan, Talia D. Wiggen, Adam J. Gilbertsen, Marshall I. Hertz, Ryan C. Hunter, Robert A. Quinn
BackgroundProgression of chronic lung disease often leads to the requirement for a lung transplant (LTX). Despite improvements in short-term survival after LTX, chronic lung allograft dysfunction (CLAD) remains a critical challenge for long-term surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d39d7192f9fe686143feca5359c0927
https://doi.org/10.1101/2022.11.16.22281980
https://doi.org/10.1101/2022.11.16.22281980
Autor:
Hong Xia, Alexey Benyumov, Craig A. Henke, Peter B. Bitterman, Jeremy Herrera, Libang Yang, Emilian Racila, Karen Smith, Adam J Gilbertsen
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Despite modest improvement in patient outcomes from recent advances in pharmacotherapy targeting fibrogenic signaling pathways, idiopathic pulmonary fibrosis (IPF) remains a major unsolved clinical problem. One reason for this is that available antif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d61b27e1839ff838c9a5e77a4772b64
https://doi.org/10.1152/ajplung.00456.2020
https://doi.org/10.1152/ajplung.00456.2020
Publikováno v:
J Med Microbiol
In the cystic fibrosis (CF) airways,Pseudomonas aeruginosaundergoes diverse physiological changes in response to inflammation, antibiotic pressure, oxidative stress and a dynamic bioavailable nutrient pool. These include loss-of-function mutations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d21a0036c380d08b37aa32b27ad48
https://doi.org/10.1099/jmm.0.000928
https://doi.org/10.1099/jmm.0.000928
Autor:
Nick B Paulson, Adam J Gilbertsen, Joseph J Dalluge, Cole W Welchlin, John Hughes, Wei Han, Timothy S Blackwell, Theresa A Laguna, Bryan J Williams
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111441 (2014)
The arginine decarboxylase pathway, which converts arginine to agmatine, is present in both humans and most bacterial pathogens. In humans agmatine is a neurotransmitter with affinities towards α2-adrenoreceptors, serotonin receptors, and may inhibi
Externí odkaz:
https://doaj.org/article/bc39a391a1704780b513dcbbf2e069db
Autor:
Adam J Gilbertsen, Hong Xia, Libang Yang, Craig A. Henke, Karen Smith, Daniel Beisang, Jonathan Kuo, Peter B. Bitterman
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 9 (2021)
JCI Insight, Vol 6, Iss 9 (2021)
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease. We previously identified fibrogenic mesenchymal progenitor cells (MPCs) in the lungs of patients with IPF who serve as drivers of progressive fibrosis. Recent single-cell RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09dcfe640fb45c9d438e58c5e564c5b5
https://doi.org/10.1172/jci.insight.144652
https://doi.org/10.1172/jci.insight.144652
Autor:
Libang Yang, Brian J Sandri, Daniel Beisang, Jeremy Herrera, Alexey Benyumov, Eric F. Lock, Karen Smith, Adam J Gilbertsen, Emilian Racila, Craig A. Henke, Colleen L. Forster, Peter B. Bitterman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
In Idiopathic Pulmonary Fibrosis (IPF), there is unrelenting scarring of the lung mediated by pathological mesenchymal progenitor cells (MPCs) that manifest autonomous fibrogenicity in xenograft models. To determine where along their differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66755c0c5a7977ca000b9c8e84d5880
http://europepmc.org/articles/PMC7341888
http://europepmc.org/articles/PMC7341888
Autor:
Karen Smith, Libang Yang, Hong Xia, Peter B. Bitterman, S. Khalil, Adam J Gilbertsen, Craig A. Henke
Publikováno v:
D109. MODULATING THE FIBROTIC RESPONSE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66f67990ffba4421fb846b612498dc0b
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7877
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7877
Autor:
Craig A. Henke, Karen Smith, Adam J Gilbertsen, Alexey Benyumov, Hong Xia, Peter B. Bitterman, Libang Yang, Jeremy Herrera
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the mechanisms driving progression remain incompletely defined. We previously reported that the IPF lung harbors fibrogenic mesenchymal progenitor cells (MPCs), which ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e0687c791f0c44158f747d76f4e3bf
https://doi.org/10.1152/ajplung.00200.2017
https://doi.org/10.1152/ajplung.00200.2017
Autor:
A. Bunyemov, Daniel Beisang, Peter B. Bitterman, Craig A. Henke, Adam J Gilbertsen, Jeremy Herrera, Karen Smith
Publikováno v:
C64. PULMONARY FIBROSIS MODELS AND MECHANISTIC INSIGHTS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ab9570b60649dd7aa8bf8ec5d9e922
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5394
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5394