Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adam J. Filgo"'
Publikováno v:
Comp Med
Pregnant rabbits are a common nonrodent model for reproductive safety evaluation in preclinical drug development. During reproductive toxicology studies, rabbits are prone to decreased food consumption and anorexia. When persistent or severe, this co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ff898f9fb30678c1060a02e689205b
https://doi.org/10.30802/aalas-cm-19-000007
https://doi.org/10.30802/aalas-cm-19-000007
Autor:
Adam J. Filgo, Justin D. Vidal
Publikováno v:
Current Protocols in Mouse Biology
Evaluation of the female reproductive system is an important part of basic reproductive biology research, toxicology testing, and mutant mouse phenotype assessment. The female reproductive system is dynamic and the onset of puberty and the normal cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d807081d0f1060e92b82666ed6b561
https://doi.org/10.1002/cpmo.35
https://doi.org/10.1002/cpmo.35
Autor:
Adam J. Filgo, Aditi R. Borde, Bentley R. Midkiff, Julie F. Foley, Casey E. Reed, Vesna A. Chappell, Lydia B. Alexander, Pretish R. Borde, Melissa A. Troester, Schantel A. Hayes Bouknight, Samantha Puvanesarajah, Suzanne E. Fenton
Publikováno v:
Toxicologic Pathology. 44:1034-1058
There are currently no reports describing mammary gland development in the Harlan Sprague-Dawley (HSD) rat, the current strain of choice for National Toxicology Program (NTP) testing. Our goals were to empower the NTP, contract labs, and other resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec273ea0ca2a689dc13f798e7ca9b3ee
https://doi.org/10.1177/0192623316663864
https://doi.org/10.1177/0192623316663864
Autor:
Justin D, Vidal, Adam J, Filgo
Publikováno v:
Current protocols in mouse biology. 7(4)
Evaluation of the female reproductive system is an important part of basic reproductive biology research, toxicology testing, and mutant mouse phenotype assessment. The female reproductive system is dynamic and the onset of puberty and the normal cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00476a096f7c85fd7d822731432ace36
https://pubmed.ncbi.nlm.nih.gov/29261233
https://pubmed.ncbi.nlm.nih.gov/29261233
Autor:
Adam J. Filgo, Ali S. Faqi
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493972067
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ec469f71bb3eac6a8cf2117ba59457
https://doi.org/10.1007/7653_2017_69
https://doi.org/10.1007/7653_2017_69
Autor:
Dennis A. Simpson, Adam J. Filgo, Nancy E. Thomas, Janiel M. Shields, Bernard Omolo, Maria J. Sambade, Craig C. Carson, Joseph G. Ibrahim, William K. Kaufmann
Publikováno v:
Environmental and Molecular Mutagenesis. 55:457-471
A systems biology approach was applied to investigate the mechanisms of chromosomal instability in melanoma cell lines. Chromosomal instability was quantified using array comparative genomic hybridization to identify somatic copy number alterations (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218e5cacbe8726a49d66595ee705f2cd
https://doi.org/10.1002/em.21859
https://doi.org/10.1002/em.21859
Autor:
Mark J. Hoenerhoff, Amy E. Brix, Adam J. Filgo, Erin M. Quist, Suzanne E. Fenton, Grace E. Kissling
Perfluorooctanoic acid (PFOA) is a ubiquitous pollutant that causes liver toxicity in rodents, a process believed to be dependent on peroxisome proliferator–activated receptor-alpha (PPARα) activation. Differences between humans and rodents have m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb5644365d4a3d6d829b79e3934d239
https://europepmc.org/articles/PMC4431958/
https://europepmc.org/articles/PMC4431958/
Autor:
Suzanne E. Fenton, Adam J. Filgo, Connie A. Cummings, Erin M. Quist, Grace E. Kissling, Mark J. Hoenerhoff
Perfluorooctanoic acid (PFOA) is a perfluoroalkyl acid primarily used as an industrial surfactant. It persists in the environment and has been linked to potentially toxic and/or carcinogenic effects in animals and people. As a known activator of pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f7f2abca004c8eb321c41475b692dd
https://europepmc.org/articles/PMC4400180/
https://europepmc.org/articles/PMC4400180/
Autor:
William K, Kaufmann, Craig C, Carson, Bernard, Omolo, Adam J, Filgo, Maria J, Sambade, Dennis A, Simpson, Janiel M, Shields, Joseph G, Ibrahim, Nancy E, Thomas
Publikováno v:
Environmental and molecular mutagenesis. 55(6)
A systems biology approach was applied to investigate the mechanisms of chromosomal instability in melanoma cell lines. Chromosomal instability was quantified using array comparative genomic hybridization to identify somatic copy number alterations (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de467f60d4d8d2ccb9f5d62952754783
https://pubmed.ncbi.nlm.nih.gov/24616037
https://pubmed.ncbi.nlm.nih.gov/24616037