Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Adam J. Collier"'
1
Alterations to both the Primary and Predicted Secondary Structure of Stem-Loop IIIc of the Hepatitis C Virus 1b 5′ Untranslated Region (5′UTR) Lead to Mutants Severely Defective in Translation Which Cannot Be Complemented in trans by the Wild-Type 5′UTR Sequence
Autor: Shixing Tang, Adam J. Collier, Richard M. Elliott
Publikováno v: Journal of Virology. 73:2359-2364
Cap-independent translation of the hepatitis C virus (HCV) genomic RNA is mediated by an internal ribosome entry site (IRES) within the 5′ untranslated region (5′UTR) of the virus RNA. To investigate the effects of alterations to the primary sequ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ba2a72c68a5ae6b57ffd322ce6633d1
https://doi.org/10.1128/jvi.73.3.2359-2364.1999
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2
Translation efficiencies of the 5' untranslated region from representatives of the six major genotypes of hepatitis C virus using a novel bicistronic reporter assay system
Autor: Shixing Tang, Adam J. Collier, Richard M. Elliott
Publikováno v: Journal of General Virology. 79:2359-2366
The 5' untranslated region (5'UTR) of hepatitis C virus (HCV) contains an internal ribosome entry site (IRES) which directs translation of the viral open reading frame (ORF). The 5'UTR is highly conserved between virus isolates in both primary sequen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da00983a12e3c25d255b46d63047e2a4
https://doi.org/10.1099/0022-1317-79-10-2359
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3
TGF-β isoforms fail to modulate inositol phosphates and cAMP in normal and tumour-derived human oral keratinocytes
Autor: KA Elsegood, Jonathan R Sandy, Adam J. Collier, Ian C. Paterson, Stephen S. Prime, W. Andrew Yeudall
Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1315(2):117-122
This study examined inositol phosphate and cAMP regulation by TGF-beta 1, -beta 2 and -beta 3 in normal and tumour-derived human oral keratinocytes. Previous findings indicated that the cell lines expressed TGF-beta cell surface receptors and had a r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894e1b3c21d054a524bda46417d3dd39
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4
The binding of hepatitis A virus to cell surfaces shows evidence of positive co-operativity
Autor: Adam J. Collier, Adrian J. Wolstenholme
Publikováno v: FEMS microbiology letters. 116(2)
Radio-iodinated hepatitis A virus binds to cultured mammalian cells in a saturable manner, with about 1.4 x 10(3) sites/cell and a S0.5 of about 1.4 x 10(-11) M for FRhK-4 cells. This binding to FRhK-4 cells shows evidence of positive co-operativity,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35587f5f65cf863910aa07ad1c0cf383
https://pubmed.ncbi.nlm.nih.gov/8150262
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