Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Adam J Rosenberg"'
Autor:
Adam J. Rosenberg, Yiu-Yin Cheung, Fei Liu, Carina Sollert, Todd E. Peterson, Jonathan A. Kropski
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Background Radiopharmaceuticals capable of targeting the fibroblast activation protein have become widely utilized in the research realm as well as show great promise to be commercialized; with [68Ga]Ga-FAPI-46 being one of the most widely u
Externí odkaz:
https://doaj.org/article/a89be5f949a74202b6834c4ed739c8ca
Autor:
William J. Behof, Clayton A. Whitmore, Justin R. Haynes, Adam J. Rosenberg, Mohammed N. Tantawy, Todd E. Peterson, Fiona E. Harrison, Robert B. Beelman, Wellington Pham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Ergothioneine (ERGO) is a rare amino acid mostly found in fungi, including mushrooms, with recognized antioxidant activity to protect tissues from damage by reactive oxygen species (ROS) components. Prior to this publication, the biodistribu
Externí odkaz:
https://doaj.org/article/9f1da49055e5462fa3b225a7997b562e
Autor:
Clayton A. Whitmore, Justin R. Haynes, William J. Behof, Adam J. Rosenberg, Mohammed N. Tantawy, Brian C. Hachey, Brian E. Wadzinski, Benjamin W. Spiller, Todd E. Peterson, Krista C. Paffenroth, Fiona E. Harrison, Robert B. Beelman, Printha Wijesinghe, Joanne A. Matsubara, Wellington Pham
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 742 (2022)
Background: Ergothioneine (ERGO) is a unique antioxidant and a rare amino acid available in fungi and various bacteria but not in higher plants or animals. Substantial research data indicate that ERGO is a physiological antioxidant cytoprotectant. Di
Externí odkaz:
https://doaj.org/article/882ef7134def4279bbf43586617325cc
Autor:
Adam J. Rosenberg, Yiu‐Yin Cheung, Fei Liu, Todd E. Peterson, James Silverman, Ciaran M. Considine, Daniel O. Claassen
Publikováno v:
J Labelled Comp Radiopharm
(R)-[(18)F]MH.MZ ([(18)F]MH.MZ) is a promising positron emission tomography (PET) radiotracer for in vivo study of the 5-HT(2A) receptor. To facilitate clinical trials a fully automated radiosynthesis procedure for [(18)F]MH.MZ was developed using co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52aaf7733a13317653769004f07c086
https://doi.org/10.1002/jlcr.3975
https://doi.org/10.1002/jlcr.3975
Autor:
Clayton A. Whitmore, Mariam I. Boules, William J. Behof, Justin R. Haynes, Dmitry Koktysh, Adam J. Rosenberg, Mohammed N. Tantawy, Wellington Pham
Publikováno v:
Molecules, Vol 26, Iss 8, p 2182 (2021)
Promethazine, an antihistamine drug used in the clinical treatment of nausea, has been demonstrated the ability to bind Abeta in a transgenic mouse model of Alzheimer’s disease. However, so far, all of the studies were performed in vitro using extr
Externí odkaz:
https://doaj.org/article/cfd2eccd08f44b15bb163737bf294d85
Autor:
Alexander C Conley, Tonnar Castellano, Brian Boyd, John Patrick Begnoche, Adam J Rosenberg, Sepideh Shokouhi, Julie Dumas, Paul A Newhouse
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e3a7a21339c7aeb5d03f2b28a737c8
https://doi.org/10.1002/alz.061591
https://doi.org/10.1002/alz.061591
Autor:
Vivian T. Jones, Ramona Graves-Deal, KyuOK Jeon, Adam J. Rosenberg, Zheng Cao, Galina T. Bogatcheva, Sarah J. Harmych, James N. Higginbotham, Kwangho Kim, James W. Janetka, Gary A. Sulikowski, Bhuminder Singh
Publikováno v:
Cancer Research. 83:2562-2562
We have previously identified that in the absence of MET amplification or mutation, RTK hyperphosphorylation, indicative of its active state, may contribute to resistance to the EGFR-directed therapeutic, cetuximab in colorectal cancer (CRC). In our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd148fc0e4814c87a708fcabf1a3f0a9
https://doi.org/10.1158/1538-7445.am2023-2562
https://doi.org/10.1158/1538-7445.am2023-2562
Autor:
William J. Behof, Clayton A. Whitmore, Justin R. Haynes, Adam J. Rosenberg, Mohammed N. Tantawy, Todd E. Peterson, Fiona E. Harrison, Robert B. Beelman, Printha Wijesinghe, Joanne A. Matsubara, Wellington Pham
Publikováno v:
FEBS Lett
L-ergothioneine (ERGO) is a potent antioxidant with cytoprotective effects. To study ERGO biodistribution and detect oxidative stress in vivo, we report an efficient and reproducible preparation of [(11)C]-labeled ERGO PET radioligand based on protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a3179676c810d41d50e7238d539bc3
https://pubmed.ncbi.nlm.nih.gov/35100442
https://pubmed.ncbi.nlm.nih.gov/35100442
Autor:
Mohammed N. Tantawy, Todd E. Peterson, Clayton A. Whitmore, Robert B. Beelman, Justin R. Haynes, Fiona E. Harrison, Adam J. Rosenberg, Wellington Pham, William J. Behof
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Ergothioneine (ERGO) is a rare amino acid mostly found in fungi, including mushrooms, with recognized antioxidant activity to protect tissues from damage by reactive oxygen species (ROS) components. Prior to this publication, the biodistribution of E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638cf9d4a0f5142465258cad4abb138b
http://europepmc.org/articles/PMC8446031
http://europepmc.org/articles/PMC8446031
Publikováno v:
Journal of periodontologyREFERENCES. 93(1)
BACKGROUND: It is well known that following root surface debridement (RSD) residual deposits remain. Periodontal endoscopy has provided a method of directly visualizing root surfaces during periodontal debridement in an intact pocket without the need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff9d068970391b23e3e6ea37a5ee246
https://pubmed.ncbi.nlm.nih.gov/33909914
https://pubmed.ncbi.nlm.nih.gov/33909914