Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Adam J Moeser"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171617 (2017)
Psychosocial stress is a major factor driving gastrointestinal (GI) pathophysiology and disease susceptibility in humans and animals. The mechanisms governing susceptibility to stress-induced GI disease remain poorly understood. In the present study,
Externí odkaz:
https://doaj.org/article/70d49ea8c61e4898bd03bb54dc74ebc3
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59838 (2013)
The clinical onset and severity of intestinal disorders in humans and animals can be profoundly impacted by early life stress. Here we investigated the impact of early weaning stress in pigs on intestinal physiology, clinical disease, and immune resp
Externí odkaz:
https://doaj.org/article/6d4cefa24b254d28a75f65a39025035f
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39935 (2012)
Psychological stress is a predisposing factor in the onset and exacerbation of important gastrointestinal diseases including irritable bowel syndrome (IBS) and the inflammatory bowel diseases (IBD). The pathophysiology of stress-induced intestinal di
Externí odkaz:
https://doaj.org/article/f595e22590a045e4aa0dcf261c5b3210
Autor:
Mahsa Fardisi, Kyan Thelen, Allegra Groenendal, Mrigendra Rajput, Kimberly Sebastian, G. Andres Contreras, Adam J. Moeser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract During the early pre and postnatal life, host and environmental factors can impart a major influence on immune development, thus shaping lifelong disease resistance. Two major factors known to influence immune function and mortality in anima
Externí odkaz:
https://doaj.org/article/3b20aa4588db485cbed9fefff2ead2ab
Autor:
Emily Mackey, Adam J. Moeser
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(10)
Mast cells are critical innate immune effectors located throughout the body that are crucial for host defense mechanisms via orchestrating immune responses to a variety of host and environmental stimuli necessary for survival. The role of mast cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1503443a3628675bf223f75301bd0ce2
https://pubmed.ncbi.nlm.nih.gov/35817512
https://pubmed.ncbi.nlm.nih.gov/35817512
Autor:
Adrian M. Piliponsky, Kavita Sharma, Phoenicia Quach, Alyssa Brokaw, Shayla Nguyen, Austyn Orvis, Siddhartha S. Saha, Nyssa Becker Samanas, Ravin Seepersaud, Yu Ping Tang, Emily Mackey, Gauri Bhise, Claire Gendrin, Anna Furuta, Albert J. Seo, Eric Guga, Irina Miralda, Michelle Coleman, Erin L. Sweeney, Charlotte A. Bäuml, Diana Imhof, Jessica M. Snyder, Adam J. Moeser, Lakshmi Rajagopal
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
Invasive bacterial infections remain a major cause of human morbidity. Group B streptococcus (GBS) are Gram-positive bacteria that cause invasive infections in humans. Here, we show that factor XIIIA–deficient (FXIIIA-deficient) female mice exhibit
Externí odkaz:
https://doaj.org/article/333d9ff9ad8b4e0e97c66e4897ce00b5
Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Yan Wu, Adam J. Moeser, George I. Mias, Alfred J. Robison, Jin He
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Yuen Gao et al. characterize deficits in brain morphology, behavior, and gene expression following genetic ablation of the histone methyltransferase, ASH1L, during brain development in mice. Their results provide new insight into links between ASH1L
Externí odkaz:
https://doaj.org/article/4b96d495f04d482b9a52d8c90fd24875
Autor:
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Adam J. Moeser, George I. Mias, Alfred J. Robison, Yi Zhang, Jin He
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103742- (2022)
Summary: Recent clinical studies report that chromosomal 12q24.31 microdeletions are associated with autism spectrum disorder (ASD) and intellectual disability (ID). However, the causality and underlying mechanisms linking 12q24.31 microdeletions to
Externí odkaz:
https://doaj.org/article/7c4859cbe5774588b7eece70ffe4b2db
Publikováno v:
Animal Nutrition, Vol 3, Iss 4, Pp 313-321 (2017)
The gastrointestinal (GI) barrier serves a critical role in survival and overall health of animals and humans. Several layers of barrier defense mechanisms are provided by the epithelial, immune and enteric nervous systems. Together they act in conce
Externí odkaz:
https://doaj.org/article/c541b27fc2dc43fbb2e4683bf9faf2c0
Autor:
Yihang Li, Kyan M. Thelen, Karina Matos Fernández, Rahul Nelli, Mahsa Fardisi, Mrigendra Rajput, Nathalie L. Trottier, Genaro A. Contreras, Adam J. Moeser
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Early-life adversity (ELA) is linked with the increased risk for inflammatory and metabolic diseases in later life, but the mechanisms remain poorly understood. Intestinal epithelial glucose transporters sodium-glucose-linked transporter 1 (SGLT1) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a594af690df1b6df1a10d2c134a53eaa
https://doi.org/10.1152/ajpgi.00207.2021
https://doi.org/10.1152/ajpgi.00207.2021