Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Adam J Mellott"'
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-39 (2022)
Abstract Wound healing is a dynamic series of interconnected events with the ultimate goal of promoting neotissue formation and restoration of anatomical function. Yet, the complexity of wound healing can often result in development of complex, chron
Externí odkaz:
https://doaj.org/article/c1ca11d1e0ef4f20aae18d344e1f892e
Autor:
Jacob G. Hodge, Sumedha Gunewardena, Richard A. Korentager, David S. Zamierowski, Jennifer L. Robinson, Adam J. Mellott
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Introduction: Wound therapies are capable of modulating the complex molecular signaling profile of tissue regeneration. However traditional, bulk tissue analysis results in nonspecific expressional profiles and diluted signaling that lacks temporal-s
Externí odkaz:
https://doaj.org/article/fd956ad4e2f048a892f697fca60a085b
Publikováno v:
Frontiers in Medical Technology, Vol 5 (2023)
IntroductionWound healing consists of a dynamic series of events that are highly dependent on paracrine factors for proper progression through the phases of wound healing. Inappropriate progression through the phases is associated with insufficient e
Externí odkaz:
https://doaj.org/article/c50386ddcc0b4e36a57170dd1ce41f13
Autor:
Athanasia Warnecke, Jennifer Harre, Matthew Shew, Adam J. Mellott, Igor Majewski, Martin Durisin, Hinrich Staecker
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Mesenchymal stromal cells (MSCs) are an adult derived stem cell-like population that has been shown to mediate repair in a wide range of degenerative disorders. The protective effects of MSCs are mainly mediated by the release of growth factors and c
Externí odkaz:
https://doaj.org/article/1ddf6581bee346c9ab38d1bcadb3854f
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245234 (2021)
Tissue engineering and gene therapy strategies offer new ways to repair permanent damage to mechanosensory hair cells (MHCs) by differentiating human Wharton's Jelly cells (HWJCs). Conventionally, these strategies require the classification of each c
Externí odkaz:
https://doaj.org/article/d7e9ff9a4e4c4bbc96abf0bf429699db
Publikováno v:
Wound Repair and Regeneration. 31:367-383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38578296803ba8398da6b93ce56d893
https://doi.org/10.1111/wrr.13076
https://doi.org/10.1111/wrr.13076
Publikováno v:
Microscopy Today. 30:30-38
Advancements in high content image analysis have led to an increase in the adoption of these techniques in basic science and clinical research. High-throughput approaches to imaging and image analysis require minimal user interventions, circumventing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c5ac2ba928f13e7335ca1e766212853
https://doi.org/10.1017/s155192952200044x
https://doi.org/10.1017/s155192952200044x
Autor:
David S. Zamierowski, Christopher A Neal, Adam J. Mellott, Richard Korentager, Molly E. Steed, Jennifer G. Nelson-Brantley, Ashley L Pistorio, Hongyan Dai, Jacob G Hodge
Publikováno v:
Wound Repair and Regeneration. 30:64-81
Negative pressure wound therapy (NPWT) is used clinically to promote tissue formation and wound closure. In this study, a porcine wound model was used to further investigate the mechanisms as to how NPWT modulates wound healing via utilization of a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47f80369c207cc482abd9b274409bad
https://doi.org/10.1111/wrr.12971
https://doi.org/10.1111/wrr.12971
Publikováno v:
Regenerative medicine. 18(1)
Aim: To compare the physiological behavior of mesenchymal stem/stromal cells (MSCs) within an expandable tissue-mimetic 3D system relative to in vitro expansion in a traditional 2D system. Methods: Adipose-derived MSCs (ASCs) were continuously cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ec0c258b0515759d3cad7b492c2510
https://pubmed.ncbi.nlm.nih.gov/36222003
https://pubmed.ncbi.nlm.nih.gov/36222003
Autor:
Christopher A Neal, Adam J. Mellott, Settimio Pacelli, Kyley Burkey, Madeline Fang, Aishik Chakraborty, Arghya Paul, Saman Modaresi, Aparna R. Chakravarti, Cecilia Kurlbaum, Siddharth Subham
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:2597-2610
Hydrogels can be fabricated and designed to exert direct control over stem cells' adhesion and differentiation. In this study, we have investigated the use of polydopamine (pDA)-treatment as a binding platform for bioactive compounds to create a vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0efc331c1f89396c92685f3d967cc
https://doi.org/10.1002/jbm.a.37253
https://doi.org/10.1002/jbm.a.37253