Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Adam J Karpala"'
Autor:
Jeffrey Butler, Cameron R Stewart, Daniel S Layton, Phouvong Phommachanh, Jennifer Harper, Jean Payne, Ryan M Evans, Stacey Valdeter, Som Walker, Gemma Harvey, Songhua Shan, Matthew P Bruce, Christina L Rootes, Tamara J Gough, Andreas Rohringer, Grantley R Peck, Sarah J Fardy, Adam J Karpala, Dayna Johnson, Jianning Wang, Bounlom Douangngeun, Christopher Morrissy, Frank Y K Wong, Andrew G D Bean, John Bingham, David T Williams
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162375 (2016)
Avian influenza viruses of H5 subtype can cause highly pathogenic disease in poultry. In March 2014, a new reassortant H5N6 subtype highly pathogenic avian influenza virus emerged in Lao People's Democratic Republic. We have assessed the pathogenicit
Externí odkaz:
https://doaj.org/article/90b51d3ecf274f8f85d67fd025eebdea
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21552 (2011)
Highly pathogenic avian influenza (HPAI) H5N1 virus is endemic in many regions around the world and remains a significant pandemic threat. To date H5N1 has claimed almost 300 human lives worldwide, with a mortality rate of 60% and has caused the deat
Externí odkaz:
https://doaj.org/article/39f9c8940e2042e392765dfbfb2b4fe3
Publikováno v:
Molecular Immunology. 63:373-380
The identification of immune pathways that protect against pathogens may lead to novel molecular therapies for both livestock and human health. Interferon (IFN) is a major response pathway that stimulates multiple genes targeted towards reducing viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0325330cc60ede70a2896a611a5aea2f
https://doi.org/10.1016/j.molimm.2014.09.011
https://doi.org/10.1016/j.molimm.2014.09.011
Autor:
Simon Burggraaf, Andrew G. D. Bean, Adam J. Karpala, Sue Lowther, John Bingham, Wayne G. Kimpton, Paul Selleck
Publikováno v:
Virus Research
Highlights • Chickens are acutely susceptible to influenza when compared with ducks. • The chicken innate immune responses to influenza are more pronounced than ducks. • IL6 is rapidly upregulated in chickens compared to ducks. • Cytokine pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f673b6b377bfeefbd52f64ef2b224ba4
http://europepmc.org/articles/PMC7127704
http://europepmc.org/articles/PMC7127704
Publikováno v:
Veterinary Immunology and Immunopathology. 148:100-109
Zoonotic viruses, such as highly pathogenic avian influenza (HPAI), present a significant threat to both the poultry industry and public health. The present method of controlling avian influenza (AI) relies on good farming practice with limited use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de1c94c94df21a76e765dd4243d1035
https://doi.org/10.1016/j.vetimm.2011.05.031
https://doi.org/10.1016/j.vetimm.2011.05.031
Autor:
Audrey Bagnaud-Baule, John W. Lowenthal, Adam J. Karpala, Kate E. Goossens, Andrew G. D. Bean
Publikováno v:
Journal of Reproductive Immunology. 94:169-174
Newborn vertebrates may be susceptible to infection because the immature status of their immune system results in an inability to make an effective immune response. Consequently, newly hatched chicks appear to be more susceptible to infections than m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40012a17c2da12e0c9f2442cde2dc28e
https://doi.org/10.1016/j.jri.2012.02.008
https://doi.org/10.1016/j.jri.2012.02.008
Autor:
Sue Lowther, Terry G. Wise, Adam J. Karpala, Peter G. Mohr, Cameron R. Stewart, Andrew G. D. Bean, John W. Lowenthal, Audrey Bagnaud-Baule
Publikováno v:
Journal of Interferon & Cytokine Research. 32:46-51
Avian influenza virus is endemic in many regions around the world and remains a pandemic threat, a scenario tied closely to outbreaks of the virus in poultry. The innate immune system, in particular the nucleic acid-sensing toll-like receptors (TLRs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f3107c99046a464d1e204f1ed9ae4b
https://doi.org/10.1089/jir.2011.0036
https://doi.org/10.1089/jir.2011.0036
Autor:
Li-Mei Chen, Adam J. Karpala, John Bingham, Ruben O. Donis, Karel A. Schat, Andrew G. D. Bean, John W. Lowenthal
Publikováno v:
Journal of Interferon & Cytokine Research. 31:393-400
To better understand the immune response to highly pathogenic avian influenza virus, we compared expression of cytokines in chickens infected with avian influenza virus (A/Vietnam/1203/04) to that in uninfected chickens. Gene expression analyses reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4373a7a31f2a3b576b7531f1cea04d0
https://doi.org/10.1089/jir.2010.0069
https://doi.org/10.1089/jir.2010.0069
Autor:
Kate E. Goossens, Terri E. O’Neil, Peter G. McWaters, Kirsten R. Morris, Andrew G. D. Bean, Mary M. Broadway, Adam J. Karpala, John W. Lowenthal
Publikováno v:
Journal of Interferon & Cytokine Research. 28:341-350
Interferons (IFN) provide a critical first line of defense against viral infection in vertebrates. Moreover, IFN-lambda, a recently identified group of mammalian IFN, has demonstrated antiviral potential in the treatment of mammalian viruses. With th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379308da7ae31848c2b1bf7a6e88c2df
https://doi.org/10.1089/jir.2007.0117
https://doi.org/10.1089/jir.2007.0117
Publikováno v:
Developmental & Comparative Immunology. 32:435-444
Toll-like receptors (TLRs) play key roles in the response to pathogens and in mammals the host response to virus critically relies on TLR3 to detect viral-derived dsRNA. However, in chickens there is a paucity of information about this pathway, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e849285dfb75d5e5eb6c065d83e30d7c
https://doi.org/10.1016/j.dci.2007.08.004
https://doi.org/10.1016/j.dci.2007.08.004