Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Adam J Hockenberry"'
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268883 (2022)
Synthetic biology has successfully advanced our ability to design and implement complex, time-varying genetic circuits to control the expression of recombinant proteins. However, these circuits typically require the production of regulatory genes who
Externí odkaz:
https://doaj.org/article/27002357ebd44c3d831f4cf469f79ef3
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206634 (2018)
Cells respond to changing nutrient availability and external stresses by altering the expression of individual genes. Condition-specific gene expression patterns may thus provide a promising and low-cost route to quantifying the presence of various s
Externí odkaz:
https://doaj.org/article/1ad794ef4470434c8b57c943a99719a1
Autor:
Elle C. Moore, Gerard C. Blobe, Nicholas C. DeVito, Brent A. Hanks, Michael R. Harrison, Christopher J. Hoimes, Jingquan Jia, Michael A. Morse, Parvathy Jayaprakasan, Andrew MacKelfresh, Hillary Mulder, Adam J. Hockenberry, Alia Zander, Martin C. Stumpe, Jackson Michuda, Kyle A. Beauchamp, Eric Perakslis, Timothy Taxter, Daniel J. George
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19394-19405 (2023)
Abstract Background Roughly 5% of metastatic cancers present with uncertain origin, for which molecular classification could influence subsequent management; however, prior studies of molecular diagnostic classifiers have reported mixed results with
Externí odkaz:
https://doaj.org/article/b59390dd42bb4274953a6323c81735b6
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 6, p e1002106 (2011)
NMDA receptors (NMDARs) are the major mediator of the postsynaptic response during synaptic neurotransmission. The diversity of roles for NMDARs in influencing synaptic plasticity and neuronal survival is often linked to selective activation of multi
Externí odkaz:
https://doaj.org/article/b02395e21f354237954acec8a4383fb1
Autor:
Liang Lin, Weston Kightlinger, Sunaina Kiran Prabhu, Adam J. Hockenberry, Chao Li, Lai-Xi Wang, Michael C. Jewett, Milan Mrksich
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 144-154 (2020)
Externí odkaz:
https://doaj.org/article/589e77929a724b96ba3469489df5b045
Autor:
Adam J. Hockenberry, Claus O. Wilke
Publikováno v:
PeerJ, Vol 9, p e11396 (2021)
Bacteriophages are broadly classified into two distinct lifestyles: temperate and virulent. Temperate phages are capable of a latent phase of infection within a host cell (lysogenic cycle), whereas virulent phages directly replicate and lyse host cel
Externí odkaz:
https://doaj.org/article/d0084d04a62445a1ad905b28b40c8c06
Autor:
Nikolay A. Aleksashin, Margus Leppik, Adam J. Hockenberry, Dorota Klepacki, Nora Vázquez-Laslop, Michael C. Jewett, Jaanus Remme, Alexander S. Mankin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The tethered ribosome system Ribo-T supports cell proliferation though at a reduced rate. Here the authors show this is due to slower ribosome assembly instead of reduced functionality.
Externí odkaz:
https://doaj.org/article/dd41dd2510804c7598e1969fe536f5bc
Autor:
Jackson Michuda, Alessandra Breschi, Joshuah Kapilivsky, Kabir Manghnani, Calvin McCarter, Adam J. Hockenberry, Brittany Mineo, Catherine Igartua, Joel T. Dudley, Martin C. Stumpe, Nike Beaubier, Maryam Shirazi, Ryan Jones, Elizabeth Morency, Kim Blackwell, Justin Guinney, Kyle A. Beauchamp, Timothy Taxter
Publikováno v:
Molecular Diagnosis & Therapy.
Cancers assume a variety of distinct histologies and may originate from a myriad of sites including solid organs, hematopoietic cells, and connective tissue. Clinical decision making based on consensus guidelines such as NCCN is often predicated on a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 11, Pp 3467-3474 (2016)
Efficient and accurate protein synthesis is crucial for organismal survival in competitive environments. Translation efficiency (the number of proteins translated from a single mRNA in a given time period) is the combined result of differential trans
Externí odkaz:
https://doaj.org/article/1e9934723e52437da4c09871883226ac
Publikováno v:
mSystems, Vol 3, Iss 5 (2018)
ABSTRACT Neisseria gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection. We tested which strain FA1090 genes show differential transcrip
Externí odkaz:
https://doaj.org/article/ccfad75e373143b7b90e76b0ed623828