Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Adam J Gormley"'
Autor:
Zachary Finkel, Fatima Esteban, Brianna Rodriguez, Tanner Clifford, Adelina Joseph, Hani Alostaz, Mridul Dalmia, Juan Gutierrez, Matthew J. Tamasi, Samuel Ming Zhang, Jonah Simone, Hafize Petekci, Susmita Nath, Miriam Escott, Shivam Kumar Garg, Adam J. Gormley, Suneel Kumar, Sonia Gulati, Li Cai
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00362- (2024)
Genomic screened homeobox 1 (Gsx1 or Gsh1) is a neurogenic transcription factor required for the generation of excitatory and inhibitory interneurons during spinal cord development. In the adult, lentivirus (LV) mediated Gsx1 expression promotes neur
Externí odkaz:
https://doaj.org/article/f01b4eae704842cea72b577e97bd7cfd
Autor:
Lauren M. Timmins, Alexandra M. Burr, Kristina Carroll, Robert Keefe, Matthew Teryek, Louis J. Cantolupo, Johannes C. M. van der Loo, Thomas R.J. Heathman, Adam J Gormley, David Smith, Biju Parekkadan
Publikováno v:
Cell Transplantation, Vol 30 (2021)
When considering the development pathway for a genetically modified cell therapy product, it is critically important that the product is engineered consistent with its intended human use. For scientists looking to develop and commercialize a new tech
Externí odkaz:
https://doaj.org/article/91127e337b6748c391d23c6b3e15f54f
Autor:
Jules Lee, Prajakatta Mulay, Matthew J. Tamasi, Jonathan Yeow, Molly M. Stevens, Adam J. Gormley
Publikováno v:
Digital Discovery. 2:219-233
Oxygen tolerant polymerizations including Photoinduced Electron/Energy Transfer-Reversible Addition–Fragmentation Chain-Transfer (PET-RAFT) polymerization allow for high-throughput synthesis of diverse polymer architectures on the benchtop in paral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c7c1fc4af1401be516f7ad4f4e3016
https://doi.org/10.1039/d2dd00100d
https://doi.org/10.1039/d2dd00100d
Autor:
Rahul Upadhya, Elena Di Mare, Matthew J. Tamasi, Shashank Kosuri, N. Sanjeeva Murthy, Adam J. Gormley
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:440-450
Polymer-protein hybrids can be deployed to improve protein solubility and stability in denaturing environments. While previous work used robotics and active machine learning to inform new designs, further biophysical information is required to ascert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd927001518a9388ea0748604896f71
https://doi.org/10.1002/jbm.a.37479
https://doi.org/10.1002/jbm.a.37479
Publikováno v:
Advanced Intelligent Systems, Vol 2, Iss 2, Pp n/a-n/a (2020)
Controlled/living radical polymerization (CLRP) techniques are widely utilized to synthesize advanced and controlled synthetic polymers for chemical and biological applications. While automation has long stood as a high‐throughput (HTP) research to
Externí odkaz:
https://doaj.org/article/3b9d4cf5dd85447296741556589ae27e
Publikováno v:
ACS Polymers Au. 3:141-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc9585f05fa49bf02db586bb1879f42
https://doi.org/10.1021/acspolymersau.2c00037
https://doi.org/10.1021/acspolymersau.2c00037
Autor:
Adam J. Gormley
Publikováno v:
Nature Synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a2aed19ecd45d7c844248eaa49e30e
https://doi.org/10.1038/s44160-023-00302-w
https://doi.org/10.1038/s44160-023-00302-w
Autor:
Fabian Grünewald, Mats H. Punt, Elizabeth E. Jefferys, Petteri A. Vainikka, Melanie König, Valtteri Virtanen, Travis A. Meyer, Weria Pezeshkian, Adam J. Gormley, Maarit Karonen, Mark S. P. Sansom, Paulo C. T. Souza, Siewert J. Marrink
Publikováno v:
Journal of Chemical Theory and Computation, 18(12). AMER CHEMICAL SOC
Grünewald, F, Punt, M H, Jefferys, E E, Vainikka, P, König, M, Virtanen, V, Meyer, T A, Pezeshkian, W, Gormley, A, Karonen, M, Sansom, M S P, Souza, P C T & Marrink, S 2022, ' Martini 3 Coarse-Grained Force Field for Carbohydrates ', Journal of Chemical Theory and Computation, vol. 18, no. 12, pp. 7555-7569 . https://doi.org/10.1021/acs.jctc.2c00757
Grünewald, F, Punt, M H, Jefferys, E E, Vainikka, P, König, M, Virtanen, V, Meyer, T A, Pezeshkian, W, Gormley, A, Karonen, M, Sansom, M S P, Souza, P C T & Marrink, S 2022, ' Martini 3 Coarse-Grained Force Field for Carbohydrates ', Journal of Chemical Theory and Computation, vol. 18, no. 12, pp. 7555-7569 . https://doi.org/10.1021/acs.jctc.2c00757
The Martini 3 force field is a full reparametrization of the Martini coarse-grained model for biomolecular simulations. Due to the improved interaction balance, it allows for a more accurate description of condensed phase systems. In the present work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2775c6911d458d8f4bc2eddd1acc5f
https://doi.org/10.1021/acs.jctc.2c00757
https://doi.org/10.1021/acs.jctc.2c00757
Autor:
Thomas M. Osborn Popp, Adam J. Gormley, N. Sanjeeva Murthy, Ashley D. Bernstein, Andrew J. Nieuwkoop, Catherine E. Miles
Publikováno v:
ACS Applied Polymer Materials. 3:6548-6561
Predicting drug release profiles from polymer microparticles has proven challenging due to the numerous environmental and chemical factors that affect the device and influence the rate of drug rele...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aee8921f5f8c8149bc488a3b667df64
https://doi.org/10.1021/acsapm.1c01254
https://doi.org/10.1021/acsapm.1c01254
Publikováno v:
ACS Biomaterials Science & Engineering. 7:2580-2591
New biodegradable polymers are needed for use in drug delivery systems to overcome the high burst release, lack of sustained drug release, and acidic degradation products frequently observed in current formulations. Commercially available poly(lactid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c39fb016fed2e4243d0e80489fb89e5
https://doi.org/10.1021/acsbiomaterials.1c00448
https://doi.org/10.1021/acsbiomaterials.1c00448