Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adam J Fike"'
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://doaj.org/article/5b4624a722da497c9f2661a9b380baec
Autor:
Ogan K Kumova, Adam J Fike, Jillian L Thayer, Linda T Nguyen, Joshua Chang Mell, Judy Pascasio, Christopher Stairiker, Leticia G Leon, Peter D Katsikis, Alison J Carey
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008072 (2019)
Respiratory viral infections contribute substantially to global infant losses and disproportionately affect preterm neonates. Using our previously established neonatal murine model of influenza infection, we demonstrate that three-day old mice are ex
Externí odkaz:
https://doaj.org/article/f901ee8cfd604a21bde3c4e6fb64d9a9
Autor:
Sathi Babu Chodisetti, Adam J. Fike, Phillip P. Domeier, Nicholas M. Choi, Chetna Soni, Ziaur S. M. Rahman
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-10 producing B cells (B10 cells) play an important immunoregulatory role in various autoimmune and infection conditions. However, the factors that regulate their development and maintenance are incompletely understood. Recently, we and others have
Externí odkaz:
https://doaj.org/article/0379784cda97449b9d4f6aff24fdd7f5
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6949a79f1dcda70f27e94b25331860
https://doi.org/10.7554/elife.84708.sa2
https://doi.org/10.7554/elife.84708.sa2
Autor:
Alison J. Carey, Jennifer L. Hope, Yvonne M. Mueller, Adam J. Fike, Ogan K. Kumova, David B. H. van Zessen, Eric A. P. Steegers, Mirjam van der Burg, Peter D. Katsikis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD
Externí odkaz:
https://doaj.org/article/33ca660065a440099528ad2eaf188cfc
Autor:
Jennifer L. Hope, Christopher J. Stairiker, Panagiota I. Spantidea, Donald T. Gracias, Alison J. Carey, Adam J. Fike, Marjan van Meurs, Inge Brouwers-Haspels, Laurine C. Rijsbergen, Joseph A. Fraietta, Yvonne M. Mueller, Rosemarieke C. Klop, Erietta Stelekati, E. John Wherry, Stefan J. Erkeland, Peter D. Katsikis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We report here that the expression of the transcription factor T-bet, which is known to be required for effector cytotoxic CD8+ T lymphocytes (CTL) generation and effector memory cell formation, is regulated in CTL by microRNA-155 (miR-155). Importan
Externí odkaz:
https://doaj.org/article/045e79ae899f4457b4050ae3c4bfc370
Autor:
Phillip P. Domeier, Kristen N. Bricker, Steven F. Ziegler, Nicholas M Choi, Adam J. Fike, Sara A. Luckenbill, Zia Ur Rahman, Stephanie L. Schell, Sathi Babu Chodisetti, Melinda J. Fasnacht
Publikováno v:
J Immunol
MicroRNAs (miRNAs) are involved in healthy B cell responses and the loss of tolerance in systemic lupus erythematosus (SLE), although the role of many miRNAs remains poorly understood. Dampening miR-21 activity was previously shown to reduce splenome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4a29c87d45fc56fcb71b39512bdf6
https://doi.org/10.4049/jimmunol.2001039
https://doi.org/10.4049/jimmunol.2001039
Autor:
Zissis C. Chroneos, Sathi Babu Chodisetti, Mark H. Kaplan, Zia Ur Rahman, Kristen N. Bricker, Adam J. Fike, Nicholas M Choi
Publikováno v:
ImmunoHorizons. 5:2-15
Genome-wide association studies identified variants in the transcription factor STAT4 gene and several other genes in the STAT4 signaling pathway, such as IL12A, IL12B, JAK2, and TYK2, which are associated with an increased risk of developing systemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657c316e00d979cc29f9d69a0f6b0565
https://doi.org/10.4049/immunohorizons.2000111
https://doi.org/10.4049/immunohorizons.2000111
Autor:
Scott M. Emrich, Ryan E. Yoast, Xuexin Zhang, Adam J. Fike, Yin-Hu Wang, Kristen N. Bricker, Anthony Tao, Ping Xin, Vonn Walter, Martin T. Johnson, Trayambak Pathak, Adam C. Straub, Stefan Feske, Ziaur S.M. Rahman, Mohamed Trebak
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e396a01d7ac2ecf4a599e7218f0ccbf
https://doi.org/10.1101/2022.05.06.490918
https://doi.org/10.1101/2022.05.06.490918
Autor:
Nadine Hempel, David I. Yule, Ping Xin, James Sneyd, Ryan E. Yoast, Adam J. Fike, Mohamed Trebak, Scott M. Emrich, Vonn Walter, Martin Johnson, Xuexin Zhang, Donald L. Gill
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The essential role of ORAI1 channels in receptor-evoked Ca2+ signaling is well understood, yet little is known about the physiological activation of the ORAI channel trio natively expressed in all cells. The roles of ORAI2 and ORAI3 have remained obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eed8dfccc3933f8d5cd1ec1ac7c195
https://doaj.org/article/d0bad2674967414e8be76ad70168e97d
https://doaj.org/article/d0bad2674967414e8be76ad70168e97d