Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Adam J Case"'
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164609 (2016)
Norepinephrine (NE) produces multifaceted regulatory patterns in T-lymphocytes. Recently, we have shown that NE utilizes redox signaling as evidenced by increased superoxide (O2●-) causally linked to the observed changes in these cells; however, th
Externí odkaz:
https://doaj.org/article/62ccc0dfb96045e0ac6c1a018686620e
Autor:
Trenton L Place, Matthew P Fitzgerald, Sujatha Venkataraman, Sabine U Vorrink, Adam J Case, Melissa L T Teoh, Frederick E Domann
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14617 (2011)
The prolyl-hydroxylase domain family of enzymes (PHD1-3) plays an important role in the cellular response to hypoxia by negatively regulating HIF-α proteins. Disruption of this process can lead to up-regulation of factors that promote tumorigenesis.
Externí odkaz:
https://doaj.org/article/ace99e10296643929e7be453ab29d666
Autor:
Mandakh Bekhbat, John Drake, Emily C. Reed, Tatlock H. Lauten, Tamara Natour, Vladimir I. Vladimirov, Adam J. Case
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 34, Iss , Pp 100690- (2023)
Psychosocial stress has been shown to prime peripheral innate immune cells, which take on hyper-inflammatory phenotypes and are implicated in depressive-like behavior in mouse models. However, the impact of stress on cellular metabolic states that ar
Externí odkaz:
https://doaj.org/article/855272ad0ca741118e6630d5dbdc1818
Autor:
Emily C. Reed, Adam J. Case
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Post-traumatic stress disorder (PTSD) is a mental health disorder that arises after experiencing or witnessing a traumatic event. Despite affecting around 7% of the population, there are currently no definitive biological signatures or biomarkers use
Externí odkaz:
https://doaj.org/article/93d9686e8e3045e696a65a91ca91f265
Publikováno v:
Brain, Behavior, and Immunity. 104:18-28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9603e2ed2db102324ae1f4b1165b40
https://doi.org/10.1016/j.bbi.2022.05.007
https://doi.org/10.1016/j.bbi.2022.05.007
Autor:
Diane L. Costanzo-Garvey, Adam J. Case, Gabrielle F. Watson, Massar Alsamraae, Arpita Chatterjee, Rebecca E. Oberley-Deegan, Samikshan Dutta, Maher Y. Abdalla, Tammy Kielian, Merry L. Lindsey, Leah M. Cook
Publikováno v:
Clinical & Experimental Metastasis. 39:641-659
Bone metastatic prostate cancer (BM-PCa) remains one of the most difficult cancers to treat due to the complex interactions of cancer and stromal cells. We previously showed that bone marrow neutrophils elicit an anti-tumor immune response against BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42832224687a893f79c85dfa9666809f
https://doi.org/10.1007/s10585-022-10170-x
https://doi.org/10.1007/s10585-022-10170-x
Autor:
James J. Mezhir, Douglas R. Spitz, Frederick E. Domann, Michael D. Henry, Jeffery Keene, Robert A. Beardsley, Wendy Cozen, Brenda Y. Hernandez, Charles F. Lynch, Garry R. Buettner, Brett A. Wagner, Sean Altekruse, Adam J. Case, Bryan G. Allen, Anna M. Button, Jennifer E. Hrabe, Andrew M. Bellizzi, Melissa A. Fath, Brianne R. O'Leary
Purpose: Pancreatic ductal adenocarcinoma (PDA) cells are known to produce excessive amounts of reactive oxygen species (ROS), particularly superoxide, which may contribute to the aggressive and refractory nature of this disease. Extracellular supero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eae4856d3131fd3f32d129a044172b5
https://doi.org/10.1158/1078-0432.c.6524636
https://doi.org/10.1158/1078-0432.c.6524636
Autor:
James J. Mezhir, Douglas R. Spitz, Frederick E. Domann, Michael D. Henry, Jeffery Keene, Robert A. Beardsley, Wendy Cozen, Brenda Y. Hernandez, Charles F. Lynch, Garry R. Buettner, Brett A. Wagner, Sean Altekruse, Adam J. Case, Bryan G. Allen, Anna M. Button, Jennifer E. Hrabe, Andrew M. Bellizzi, Melissa A. Fath, Brianne R. O'Leary
Supplementary Figures 1-3. S1: Creation and characterization of EcSOD stably expressing PDA cell lines.; S2: Activity of EcSOD activity from stably expression PDA cell lines; S3: L-NNA decreases NOS activity in PDA cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63919690b745739c526d32753ff4044
https://doi.org/10.1158/1078-0432.22460894
https://doi.org/10.1158/1078-0432.22460894
Autor:
James J. Mezhir, Douglas R. Spitz, Frederick E. Domann, Michael D. Henry, Jeffery Keene, Robert A. Beardsley, Wendy Cozen, Brenda Y. Hernandez, Charles F. Lynch, Garry R. Buettner, Brett A. Wagner, Sean Altekruse, Adam J. Case, Bryan G. Allen, Anna M. Button, Jennifer E. Hrabe, Andrew M. Bellizzi, Melissa A. Fath, Brianne R. O'Leary
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839672d2a866796c26d91cc01f2ac59
https://doi.org/10.1158/1078-0432.22460897
https://doi.org/10.1158/1078-0432.22460897
Autor:
Cassandra M. Moshfegh, Safwan K. Elkhatib, Gabrielle F. Watson, John Drake, Zachary N. Taylor, Emily C. Reed, Tatlock H. Lauten, Amelia J. Clopp, Vladimir I. Vladimirov, Adam J. Case
Publikováno v:
Biological Psychiatry Global Open Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::211997d74f2e1aae03dea668477f940d
https://doi.org/10.1016/j.bpsgos.2022.12.002
https://doi.org/10.1016/j.bpsgos.2022.12.002