Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adam J Carlton"'
Autor:
Sherylanne Newton, Fanbo Kong, Adam J Carlton, Carlos Aguilar, Andrew Parker, Gemma F Codner, Lydia Teboul, Sara Wells, Steve D M Brown, Walter Marcotti, Michael R Bowl
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1009937 (2022)
Mammalian hearing involves the mechanoelectrical transduction (MET) of sound-induced fluid waves in the cochlea. Essential to this process are the specialised sensory cochlear cells, the inner (IHCs) and outer hair cells (OHCs). While genetic hearing
Externí odkaz:
https://doaj.org/article/43713a3fbece438394f4acc5b108fdae
Autor:
Adam J. Carlton, Jing-Yi Jeng, Fiorella C. Grandi, Francesca De Faveri, Ana E. Amariutei, Lara De Tomasi, Andrew O’Connor, Stuart L. Johnson, David N. Furness, Steve D.M. Brown, Federico Ceriani, Michael R. Bowl, Mirna Mustapha, Walter Marcotti
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114025- (2024)
Summary: Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming synapses with inner hair cells (IHCs) in the mammalian cochlea. The molecular mechanisms regulating the formation of the post-synaptic
Externí odkaz:
https://doaj.org/article/003f391f46fe499b876a09eda87c4a9d
Autor:
Jing-Yi Jeng, Adam J. Carlton, Richard J. Goodyear, Colbie Chinowsky, Federico Ceriani, Stuart L. Johnson, Tsung-Chang Sung, Yelena Dayn, Guy P. Richardson, Michael R. Bowl, Steve D.M. Brown, Uri Manor, Walter Marcotti
Publikováno v:
Molecular Therapy - Methods & Clinical Development. 26:355-370
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea2b03bcf245ef28e06a0d01e2da2d1
https://doi.org/10.1016/j.omtm.2022.07.012
https://doi.org/10.1016/j.omtm.2022.07.012
Autor:
Adam J Carlton, Jing‐Yi Jeng, Fiorella C Grandi, Francesca De Faveri, Federico Ceriani, Lara De Tomasi, Anna Underhill, Stuart L Johnson, Kevin P Legan, Corné J Kros, Guy P Richardson, Mirna Mustapha, Walter Marcotti
Publikováno v:
The EMBO Journal. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baced7399b3004f88a38741fed61eab0
https://doi.org/10.15252/embj.2022112118
https://doi.org/10.15252/embj.2022112118
Autor:
Adam J, Carlton, Jing-Yi, Jeng, Fiorella C, Grandi, Francesca, De Faveri, Federico, Ceriani, Lara, De Tomasi, Anna, Underhill, Stuart L, Johnson, Kevin P, Legan, Corné J, Kros, Guy P, Richardson, Mirna, Mustapha, Walter, Marcotti
Publikováno v:
The EMBO journalReferences.
Sensory-independent Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5deacb752e09a99a75fd023e28582225
https://pubmed.ncbi.nlm.nih.gov/36594367
https://pubmed.ncbi.nlm.nih.gov/36594367
Autor:
Lukas Rüttiger, Stuart L. Johnson, Adam J Carlton, Kevin P. Legan, Jing-Yi Jeng, Philine Marchetta, Guy P. Richardson, Richard J. Goodyear, Laura F. Corns, Csaba Harasztosi, Walter Marcotti
Publikováno v:
The Journal of Physiology. 599:2015-2036
Key points The aim was to determine whether detachment of the tectorial membrane (TM) from the organ of Corti in Tecta/Tectb-/- mice affects the biophysical properties of cochlear outer hair cells (OHCs). Tecta/Tectb-/- mice have highly elevated hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d15f54f9c4900b80472ef820361d2d9
https://doi.org/10.1113/jp280905
https://doi.org/10.1113/jp280905
Autor:
Adam J Carlton, Michael R. Bowl, Julia Halford, Steve D.M. Brown, Jing-Yi Jeng, Walter Marcotti, Matthew R. Avenarius, Merle L. Gilbert, Kimimuepigha Ebisine, Peter G. Barr-Gillespie, Federico Ceriani, Anna Underhill
Publikováno v:
The Journal of Physiology
Key points Mechanoelectrical transduction at auditory hair cells requires highly specialized stereociliary bundles that project from their apical surface, forming a characteristic graded ‘staircase’ structure.The morphogenesis and maintenance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9368ad2ef56b862a865c36c867166d4c
https://doi.org/10.1113/jp280670
https://doi.org/10.1113/jp280670
Autor:
Carlos A. Aguilar, Michael R. Bowl, Adam J Carlton, Steve D.M. Brown, Sara Wells, Fanbo Kong, Lydia Teboul, Andrew Parker, Walter Marcotti, Gemma F. Codner, Sherylanne Newton
Mammalian hearing involves the mechanoelectrical transduction (MET) of sound-induced fluid waves in the cochlea. Essential to this process are the specialised sensory cochlear cells, the inner (IHCs) and outer hair cells (OHCs). While genetic hearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c795668b4d8afabbb61948f4053eca76
https://doi.org/10.1101/2021.11.10.468016
https://doi.org/10.1101/2021.11.10.468016
Autor:
Jing-Yi, Jeng, Csaba, Harasztosi, Adam J, Carlton, Laura F, Corns, Philine, Marchetta, Stuart L, Johnson, Richard J, Goodyear, Kevin P, Legan, Lukas, Rüttiger, Guy P, Richardson, Walter, Marcotti
Publikováno v:
J Physiol
The tectorial membrane (TM) is an acellular structure of the cochlea that is attached to the stereociliary bundles of the outer hair cells (OHCs), electro-motile cells that amplify motion of the cochlear partition and sharpen its frequency selectivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b93afcadf27482a13b0bbb9a84bf7d7
https://pubmed.ncbi.nlm.nih.gov/33559882
https://pubmed.ncbi.nlm.nih.gov/33559882
Autor:
David N. Furness, Stuart L. Johnson, Mirna Mustapha, Sara Wells, Michael R. Bowl, Adam J Carlton, Jing-Yi Jeng, Walter Marcotti, Lara De Tomasi, Matthew C. Holley, Francesca De Faveri, Steve D. M. Brown, Richard J. Goodyear, Guy P. Richardson
Publikováno v:
J Physiol
KEY POINTS: Age-related hearing loss (ARHL) is a very heterogeneous disease, resulting from cellular senescence, genetic predisposition and environmental factors (e.g. noise exposure). Currently, we know very little about age-related changes occurrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7346221ac5c690cdec1f8d2991c3bc5f
https://eprints.keele.ac.uk/9605/1/JP279795.pdf
https://eprints.keele.ac.uk/9605/1/JP279795.pdf