Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Adam J Bass"'
Autor:
Hui Zheng, Eirini Pectasides, Mohamed Uduman, Charles S Fuchs, James M Cleary, Adam J Bass, Jérémy Augustin, Leonie K de Klerk, Anuj K Patel, Sarah Derks, Nihal Raman, Fahire G Akarca, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Bridget Fitzpatrick, Lauren K Brais, Megan E Cavanaugh, Amanda J Rode, Melissa G Jean, Patrick H Lizotte, Matthew J Nazzaro, Peter C Enzinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/88b5dffda1124385a9d172a7073bce20
Autor:
Eric W Lin, Tatiana A Karakasheva, Dong-Jin Lee, Ju-Seog Lee, Qi Long, Adam J Bass, Kwok K Wong, Anil K Rustgi
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006938 (2017)
Advances in genomics in recent years have provided key insights into defining cancer subtypes "within-a-tissue"-that is, respecting traditional anatomically driven divisions of medicine. However, there remains a dearth of data regarding molecular pro
Externí odkaz:
https://doaj.org/article/f5a49abecdad47b5bc1da17845d3dc18
Autor:
Steven E Schumacher, Byoung Yong Shim, Giovanni Corso, Min-Hee Ryu, Yoon-Koo Kang, Franco Roviello, Gordon Saksena, Shouyong Peng, Ramesh A Shivdasani, Adam J Bass, Rameen Beroukhim
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176045 (2017)
Gastric cancer, a leading worldwide cause of cancer mortality, shows high geographic and ethnic variation in incidence rates, which are highest in East Asia. The anatomic locations and clinical behavior also differ by geography, leading to the contro
Externí odkaz:
https://doaj.org/article/48b26be9674e46519858af8338689ff3
Autor:
Yong Sang Hong, Jihun Kim, Eirini Pectasides, Cameron Fox, Seung-Woo Hong, Qiuping Ma, Gabrielle S Wong, Shouyong Peng, Matthew D Stachler, Aaron R Thorner, Paul Van Hummelen, Adam J Bass
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109440 (2014)
ERBB2-directed therapy is now a routine component of therapy for ERBB2-amplified metastatic gastroesophageal adenocarcinomas. However, there is little knowledge of the mechanisms by which these tumors develop acquired resistance to ERBB2 inhibition.
Externí odkaz:
https://doaj.org/article/a1151361100241e2881c2ca0f3850f79
Autor:
Megan C Hanna, Christina Go, Christine Roden, Robert T Jones, Panisa Pochanard, Ahmed Yasir Javed, Awais Javed, Chandrani Mondal, Emanuele Palescandolo, Paul Van Hummelen, Charles Hatton, Adam J Bass, Sung Min Chun, Deuk Chae Na, Tae-Im Kim, Se Jin Jang, Raymond U Osarogiagbon, William C Hahn, Matthew Meyerson, Levi A Garraway, Laura E MacConaill
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74950 (2013)
It has been demonstrated for some cancers that the frequency of somatic oncogenic mutations may vary in ancestral populations. To determine whether key driver alterations might occur at different frequencies in colorectal cancer, we applied a high-th
Externí odkaz:
https://doaj.org/article/a4a1da8169604c15b81e8f98eabbb7dd
Autor:
Chunyang Bao, Richard W. Tourdot, Gregory J. Brunette, Chip Stewart, Lili Sun, Hideo Baba, Masayuki Watanabe, Agoston T. Agoston, Kunal Jajoo, Jon M. Davison, Katie S. Nason, Gad Getz, Kenneth K. Wang, Yu Imamura, Robert Odze, Adam J. Bass, Matthew D. Stachler, Cheng-Zhong Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The progression of precancerous lesions to malignancy is often accompanied by increasing complexity of chromosomal alterations but how these alterations arise is poorly understood. Here we perform haplotype-specific analysis of chromosomal c
Externí odkaz:
https://doaj.org/article/283f7ed4b40c43818c5d64ef72721c07
Autor:
Laura E MacConaill, Catarina D Campbell, Sarah M Kehoe, Adam J Bass, Charles Hatton, Lili Niu, Matt Davis, Keluo Yao, Megan Hanna, Chandrani Mondal, Lauren Luongo, Caroline M Emery, Alissa C Baker, Juliet Philips, Deborah J Goff, Michelangelo Fiorentino, Mark A Rubin, Kornelia Polyak, Jennifer Chan, Yuexiang Wang, Jonathan A Fletcher, Sandro Santagata, Gianni Corso, Franco Roviello, Ramesh Shivdasani, Mark W Kieran, Keith L Ligon, Charles D Stiles, William C Hahn, Matthew L Meyerson, Levi A Garraway
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7887 (2009)
Detection of critical cancer gene mutations in clinical tumor specimens may predict patient outcomes and inform treatment options; however, high-throughput mutation profiling remains underdeveloped as a diagnostic approach. We report the implementati
Externí odkaz:
https://doaj.org/article/388609211758433580e680225740cbc3
Autor:
Walid K. Chatila, Henry Walch, Jaclyn F. Hechtman, Sydney M. Moyer, Valeria Sgambati, David M. Faleck, Amitabh Srivastava, Laura Tang, Jamal Benhamida, Dorina Ismailgeci, Carl Campos, Fan Wu, Qing Chang, Efsevia Vakiani, Elisa de Stanchina, Martin R. Weiser, Maria Widmar, Rhonda K. Yantiss, Manish A. Shah, Adam J. Bass, Zsofia K. Stadler, Lior H. Katz, Ingo K. Mellinghoff, Nilay S. Sethi, Nikolaus Schultz, Karuna Ganesh, David Kelsen, Rona Yaeger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Colitis-associated cancers (CACs) develop in patients with inflammatory bowel disease and have distinct genomic features compared to sporadic colorectal cancers. Here, the authors characterize the genomic alterations of CAC tumors and dysplasia, find
Externí odkaz:
https://doaj.org/article/a4643e58f86e4dc1a8afd07151be6e8c
Autor:
Tianxia Li, Osamu Kikuchi, Jin Zhou, Yichen Wang, Babita Pokharel, Klavdija Bastl, Prafulla Gokhale, Aine Knott, Yanxi Zhang, John G. Doench, Zandra V. Ho, Daniel V.T. Catenacci, Adam J. Bass
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
Gastroesophageal adenocarcinomas (GEAs) harbor recurrent amplification of KRAS, leading to marked overexpression of WT KRAS protein. We previously demonstrated that SHP2 phosphatase, which acts to promote KRAS and downstream MAPK pathway activation,
Externí odkaz:
https://doaj.org/article/4e331ae8a1294fbe92f680cc6ff5b939
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Figure S3 PDF file 66K,Additional data related to the proliferative and apoptotic phenotypes of CRC cells expressing mutant Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1944ab43e95e00de6e3eb39c7c552d
https://doi.org/10.1158/2159-8290.22530590
https://doi.org/10.1158/2159-8290.22530590