Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Adam J Amorese"'
Autor:
Melissa R. Iñigo, Adam J. Amorese, Michael D. Tarpey, Nicholas P. Balestrieri, Keith G. Jones, Daniel J. Patteson, Kathryn C. Jackson, Maria.J. Torres, Chien-Te Lin, Cody D. Smith, Timothy D. Heden, Shawna L. McMillin, Luke A. Weyrauch, Erin C. Stanley, Cameron A. Schmidt, Brita B. Kilburg-Basnyat, Sky W. Reece, Christine E. Psaltis, Leslie A. Leinwand, Katsu Funai, Joseph M. McClung, Kymberly M. Gowdy, Carol A. Witczak, Dawn A. Lowe, P. Darrell Neufer, Espen E. Spangenburg
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 1-15 (2020)
Objective: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skelet
Externí odkaz:
https://doaj.org/article/cef6092a71cd44739e7411b85eb621c4
Autor:
Adam J. Amorese, Alice S. Ryan
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 3 (2022)
Exercise training is an essential component in the treatment or rehabilitation of various diseases and conditions. However, barriers to exercise such as the burdens of travel or time may hinder individuals' ability to participate in such training pro
Externí odkaz:
https://doaj.org/article/a610880deb8945b79f47df750ffa0e48
Autor:
Terence E. Ryan, Cameron A. Schmidt, Michael D. Tarpey, Adam J. Amorese, Dean J. Yamaguchi, Emma J. Goldberg, Melissa M.R. Iñigo, Reema Karnekar, Allison O’Rourke, James M. Ervasti, Patricia Brophy, Thomas D. Green, P. Darrell Neufer, Kelsey Fisher-Wellman, Espen E. Spangenburg, Joseph M. McClung
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Compromised muscle mitochondrial metabolism is a hallmark of peripheral arterial disease, especially in patients with the most severe clinical manifestation — critical limb ischemia (CLI). We asked whether inflexibility in metabolism is critical fo
Externí odkaz:
https://doaj.org/article/ae9840111eff4cc6b769461964faa51a
Autor:
Cameron A Schmidt, Emma J Goldberg, Tom D Green, Reema R Karnekar, Jeffrey J Brault, Spencer G Miller, Adam J Amorese, Dean J Yamaguchi, Espen E Spangenburg, Joseph M McClung
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0225922 (2020)
Stored muscle carbohydrate supply and energetic efficiency constrain muscle functional capacity during exercise and are influenced by common physiological variables (e.g. age, diet, and physical activity level). Whether these constraints affect overa
Externí odkaz:
https://doaj.org/article/3f3a933d89974689ad73794a5bb1e8f2
Autor:
Michael D. Tarpey, Adam J. Amorese, Nicholas P. Balestrieri, Terence E. Ryan, Cameron A. Schmidt, Joseph M. McClung, Espen E. Spangenburg
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Background The ability to assess skeletal muscle function and delineate regulatory mechanisms is essential to uncovering therapeutic approaches that preserve functional independence in a disease state. Skeletal muscle provides distinct exper
Externí odkaz:
https://doaj.org/article/aaa78d16888d477bb0e9fb04b22212fc
Autor:
Andrea L. Estrada, Zackary J. Valenti, Gabriella Hehn, Adam J. Amorese, Nicholas S. Williams, Nicholas P. Balestrieri, Clayton Deighan, Christopher P. Allen, Espen E. Spangenburg, Nicole A. Kruh-Garcia, Daniel S. Lark
Publikováno v:
Am J Physiol Cell Physiol
Extracellular vesicles (EVs) are biomarkers and modifiers of human disease. EVs secreted by insulin-responsive tissues like skeletal muscle (SkM) and white adipose tissue (WAT) contribute to metabolic health and disease but the relative abundance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e4355565e43fb3ee5aad2fb6e584ea
https://doi.org/10.1152/ajpcell.00580.2020
https://doi.org/10.1152/ajpcell.00580.2020
Autor:
Adam J. Amorese, Espen E. Spangenburg, Nicholas P. Balestrieri, Kelsey H. Fisher-Wellman, Michael D. Tarpey
Publikováno v:
J Biol Chem
Doxorubicin is an anthracycline-based chemotherapeutic that causes myotoxicity with symptoms persisting beyond treatment. Patients experience muscle pain, weakness, fatigue, and atrophy, but the underlying mechanisms are poorly understood. Studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c78a790fb71889d6db4f2c659f433b7
https://doi.org/10.1074/jbc.ra119.008426
https://doi.org/10.1074/jbc.ra119.008426
Autor:
Dawn A. Lowe, Shawna L. McMillin, Joseph M. McClung, Luke A. Weyrauch, Chien-Te Lin, Leslie A. Leinwand, Timothy D. Heden, Cameron A. Schmidt, Carol A. Witczak, Christine E. Psaltis, Kymberly M. Gowdy, Kathryn C. Jackson, Adam J. Amorese, Erin C. Stanley, Espen E. Spangenburg, Brita B. Kilburg-Basnyat, Sky W Reece, Nicholas P. Balestrieri, Michael D. Tarpey, Melissa R. Iñigo, P. Darrell Neufer, Daniel J. Patteson, Keith G. Jones, Maria J. Torres, Katsuhiko Funai, Cody D. Smith
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 34, Iss, Pp 1-15 (2020)
Molecular Metabolism, Vol 34, Iss, Pp 1-15 (2020)
Objective Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acd25bfe14943d2595eb692a9f6dc5a
http://europepmc.org/articles/PMC6994285
http://europepmc.org/articles/PMC6994285
Autor:
Everett C Minchew, Joseph M. McClung, Kelsey H. Fisher-Wellman, Eli G. Hvastkovs, Espen E. Spangenburg, Michael D. Tarpey, Adam J. Amorese, Elizabeth R LaFave
Publikováno v:
Exerc Sport Sci Rev
Breast Cancer gene 1 (BRCA1) is a large, multi-functional protein that regulates a variety of mechanisms in multiple different tissues. Our work established that Brca1 is expressed in skeletal muscle and localizes to the mitochondria and nucleus. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f840b728261184b437365898fe6b546
https://pubmed.ncbi.nlm.nih.gov/34091499
https://pubmed.ncbi.nlm.nih.gov/34091499
Autor:
Adam J. Amorese, Emma J. Goldberg, Joseph M. McClung, Melissa R. Iñigo, Reema Karnekar, Cameron A. Schmidt, Dean J. Yamaguchi, Allison R. O'Rourke, Patricia Brophy, Thomas D. Green, P. Darrell Neufer, Kelsey H. Fisher-Wellman, Espen E. Spangenburg, Terence E. Ryan, James M. Ervasti, Michael D. Tarpey
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
JCI Insight
JCI Insight
Compromised muscle mitochondrial metabolism is a hallmark of peripheral arterial disease, especially in patients with the most severe clinical manifestation — critical limb ischemia (CLI). We asked whether inflexibility in metabolism is critical fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2794ace43048af80fbde5f01a2ec92de
https://doaj.org/article/ae9840111eff4cc6b769461964faa51a
https://doaj.org/article/ae9840111eff4cc6b769461964faa51a