Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Adam Hoagland"'
Autor:
Prashant Donthamsetti, Nils Winter, Adam Hoagland, Cherise Stanley, Meike Visel, Stephan Lammel, Dirk Trauner, Ehud Isacoff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In this study, the authors develop a photo-pharmacological strategy using a Membrane anchored Photoswitchable orthogonal remotely tethered agonist for the Dopamine receptor (MP-D) to selectively and reversibly modulate the D1R receptor subtype.
Externí odkaz:
https://doaj.org/article/cfcb66adbc114a23958d7e4a4ad421e8
Autor:
Chris H. Habrian, Joshua Levitz, Vojtech Vyklicky, Zhu Fu, Adam Hoagland, Isabelle McCort-Tranchepain, Francine Acher, Ehud Y. Isacoff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Metabotropic glutamate receptors (mGluRs) are dimeric G-protein–coupled receptors that operate at neural synapses. Here authors use FRET assays in live cells to monitor mGluR2/7’s activation and reveal how heterodimerization can alter the glutama
Externí odkaz:
https://doaj.org/article/118cbbd567084baca674e6ab3894b693
Autor:
Claire S Oldfield, Irene Grossrubatscher, Mario Chávez, Adam Hoagland, Alex R Huth, Elizabeth C Carroll, Andrew Prendergast, Tony Qu, Jack L Gallant, Claire Wyart, Ehud Y Isacoff
Publikováno v:
eLife, Vol 9 (2020)
Experience influences behavior, but little is known about how experience is encoded in the brain, and how changes in neural activity are implemented at a network level to improve performance. Here we investigate how differences in experience impact b
Externí odkaz:
https://doaj.org/article/3c6089e219b143c79e1661a0962f74d7
Publikováno v:
Bio-Protocol, Vol 7, Iss 7 (2017)
The objective of this protocol is to provide a detailed description for the construction and use of a behavioral apparatus, the zBox, for high-throughput behavioral measurements in larval zebrafish (Danio rerio). The zBox is used to measure behavior
Externí odkaz:
https://doaj.org/article/4998b0e8f93f4790b6e01ae19aa1955a
Autor:
Stephan Lammel, Meike Visel, Ehud Y. Isacoff, Dirk Trauner, Adam Hoagland, Prashant Donthamsetti, Nils Winter, Cherise Stanley
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Dopamine controls diverse behaviors and their dysregulation contributes to many disorders. Our ability to understand and manipulate the function of dopamine is limited by the heterogenous nature of dopaminergic projections, the diversity of neurons t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93230aedb5fcd3e5985b8f05a8d38942
https://escholarship.org/uc/item/9pw6k8w6
https://escholarship.org/uc/item/9pw6k8w6
Autor:
Andrew Prendergast, Ehud Y. Isacoff, Alex R Huth, Claire Wyart, Tony Qu, Elizabeth C. Carroll, Claire S Oldfield, Mario Chavez, Irene Grossrubatscher, Adam Hoagland, Jack L. Gallant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e49f62b9c3b64cea6ce27cf5329331
https://doi.org/10.7554/elife.56619.sa2
https://doi.org/10.7554/elife.56619.sa2
Autor:
Jack L. Gallant, Mario Chavez, Claire S Oldfield, Irene Grossrubatscher, Elizabeth C. Carroll, Claire Wyart, Ehud Y. Isacoff, Andrew Prendergast, Alex R Huth, Adam Hoagland, Tony Qu
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, pp.e56619. ⟨10.7554/eLife.56619⟩
eLife, Vol 9 (2020)
eLife, 2020, 9, pp.e56619. ⟨10.7554/eLife.56619⟩
eLife, eLife Sciences Publication, 2020, 9, pp.e56619. ⟨10.7554/eLife.56619⟩
eLife, Vol 9 (2020)
eLife, 2020, 9, pp.e56619. ⟨10.7554/eLife.56619⟩
International audience; Experience influences behavior, but little is known about how experience is encoded in the brain, and how changes in neural activity are implemented at a network level to improve performance. Here we investigate how difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19162c71f94dcb6007b34b3a478a3fdf
https://hal.archives-ouvertes.fr/hal-03019795
https://hal.archives-ouvertes.fr/hal-03019795
Autor:
Christopher J. Chang, Cheri M. Ackerman, Christine S. Liu, Bao Thai, Jefferson Y. Chan, Ehud Y. Isacoff, Adam Hoagland, Elizabeth C. Carroll, Tong Xiao, Shang Jia
Publikováno v:
Nature chemical biology
The unusually high demand for metals in the brain along with insufficient understanding of how their dysregulation contributes to neurological diseases motivates the study of how inorganic chemistry influences neural circuitry. We now report that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a356dcaf9e8a62e9ab8e0d06f62ac2
http://europepmc.org/articles/PMC6008210
http://europepmc.org/articles/PMC6008210
Publikováno v:
Bio-protocol, vol 7, iss 7
The objective of this protocol is to provide a detailed description for the construction and use of a behavioral apparatus, the zBox, for high-throughput behavioral measurements in larval zebrafish (Danio rerio). The zBox is used to measure behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe431e53e685ab4f9e26fa15867c717
https://escholarship.org/uc/item/28f6c5g9
https://escholarship.org/uc/item/28f6c5g9
Autor:
Ehud Y. Isacoff, Adam Hoagland, Zachary L. Newman, Luke P. Lee, Sabrina L. Levy, Krishan Aghi, Jun Ho Son, Kurtresha Worden
Summary Synaptic connections undergo activity-dependent plasticity during development and learning, as well as homeostatic re-adjustment to ensure stability. Little is known about the relationship between these processes, particularly in vivo. We add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abecca10635672743538bb9a7d5d063
https://europepmc.org/articles/PMC5464967/
https://europepmc.org/articles/PMC5464967/