Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Adam H. Marblestone"'
Autor:
Jing Wu, Alexandra de Paz, Bradley M. Zamft, Adam H. Marblestone, Edward S. Boyden, Konrad P. Kording, Keith E. J. Tyo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying diffic
Externí odkaz:
https://doaj.org/article/f4b1ec7d932b45bca5803a0278a5f0b6
Autor:
Young-Gyu Yoon, Peilun Dai, Jeremy Wohlwend, Jae-Byum Chang, Adam H. Marblestone, Edward S. Boyden
Publikováno v:
Frontiers in Computational Neuroscience, Vol 11 (2017)
We here introduce and study the properties, via computer simulation, of a candidate automated approach to algorithmic reconstruction of dense neural morphology, based on simulated data of the kind that would be obtained via two emerging molecular tec
Externí odkaz:
https://doaj.org/article/9422eef4172341549286b5bfaf83ed24
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212868 (2019)
We propose and theoretically study an approach to massively parallel single molecule peptide sequencing, based on single molecule measurement of the kinetics of probe binding (Havranek, et al., 2013) to the N-termini of immobilized peptides. Unlike p
Externí odkaz:
https://doaj.org/article/267a0f127cc240e0b20efcbef11be280
Autor:
Meredith Whittaker, Jonathan R. Wolpaw, Blaise Aguera y Arcas, Joseph J. Fins, Rafael Yuste, Alan Rubel, Adam H. Marblestone, Michelle Pham, Christine Mitchell, Erik Parens, Philipp Kellmeyer, Jose M. Carmena, Mina Teicher, Guo-Qiang Bi, David Wasserman, Phoebe Friesen, Norihiro Sadato, Sara Goering, Anna Wexler, Jack L. Gallant, Jane E. Huggins, Eran Klein, Laura Specker Sullivan
Publikováno v:
Neuroethics
Advancements in novel neurotechnologies, such as brain computer interfaces (BCI) and neuromodulatory devices such as deep brain stimulators (DBS), will have profound implications for society and human rights. While these technologies are improving th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64461a50e2e4fdf0046386bace9dacd
https://doi.org/10.1007/s12152-021-09468-6
https://doi.org/10.1007/s12152-021-09468-6
Publikováno v:
Current Opinion in Behavioral Sciences. 38:133-140
The classical concepts of reinforcement learning in the mammalian brain focus on dopamine release in the basal ganglia as the neural substrate of reward prediction errors, which drive plasticity in striatal and cortico-striatal synapses to maximize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af410cf89daeafd5a1a977f00775599b
https://doi.org/10.1016/j.cobeha.2021.02.019
https://doi.org/10.1016/j.cobeha.2021.02.019
Autor:
Jacob T. Robinson, Caleb Kemere, Chong Xie, Eric A. Pohlmeyer, Kenneth L. Shepard, George G. Malliaras, Malte C. Gather, John Kitching, Adam H. Marblestone, Thomas Stieglitz
Publikováno v:
IEEE sensors journal
Advances in sensing technology raise the possibility of creating neural interfaces that can more effectively restore or repair neural function and reveal fundamental properties of neural information processing. To realize the potential of these bioel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6e6aaad37c3dc8fa190217ba65fe87
https://doi.org/10.1109/jsen.2019.2931159
https://doi.org/10.1109/jsen.2019.2931159
Autor:
Eswar Prasad Ramachandran Iyer, Adam H. Marblestone, Chih-Chieh Yu, Aviv Regev, Nikhil Wagle, Nicole Cullen, Atsushi Kajita, Nikita Pak, Johanna Klughammer, Sukanya Punthambaker, Andrew C. Payne, Anubhav Sinha, Bruce E. Johnson, Ho-Jun Suk, Fei Chen, Andrew G Xue, Yi Cui, Orit Rozenblatt-Rosen, Ru Wang, Jeremy A. Miller, Daniel L Abravanel, Ana Lako, Karla Helvie, Yosuke Bando, Michal Slyper, Paul Reginato, Paul W. Tillberg, Chun-Chen Yao, Ed S. Lein, Shahar Alon, Judit Jané-Valbuena, Asmamaw T Wassie, Daniel Goodwin, Evan R. Daugharthy, Richie E. Kohman, Edward S. Boyden, George M. Church, Songlei Liu, Karl Marrett, Robert Prior, Julia Waldman, Scott J. Rodig
Methods for highly multiplexed RNA imaging are limited in spatial resolution, and thus in their ability to localize transcripts to nanoscale and subcellular compartments. We adapt expansion microscopy, which physically expands biological specimens, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7f985d5dd30287e6f6e3f0aa6afed8
https://doi.org/10.1101/2020.05.13.094268
https://doi.org/10.1101/2020.05.13.094268
Autor:
Eran Klein, Mina Teicher, Michelle Pham, Christine Mitchell, Jose M. Carmena, Judy Illes, Laura Specker Sullivan, Rafael Yuste, Jane E. Huggins, Alan Rubel, Anna Wexler, Jack L. Gallant, Phoebe Friesen, Norihiro Sadato, Meredith Whittaker, Joseph J. Fins, Adrian Carter, Philipp Kellmeyer, Blaise Aguera y Arcas, Sara Goering, David Wasserman, Guo-Qiang Bi, Erik Parens, Jonathan R. Wolpaw, Adam H. Marblestone
Publikováno v:
Nature. 551:159-163
Artificial intelligence and brain–computer interfaces must respect and preserve people's privacy, identity, agency and equality, say Rafael Yuste, Sara Goering and colleagues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0873fe45eb4ced15a4cf1a6d6c394262
https://doi.org/10.1038/551159a
https://doi.org/10.1038/551159a
Autor:
Emma K. Costa, Jeong Seuk Kang, Shoh Asano, Tay Won Shin, Narayanan Kasthuri, Amauche Emenari, Leanne Lin, Emmanouil D. Karagiannis, Edward S. Boyden, Adam H. Marblestone
Lipids are fundamental building blocks of cells and their organelles, yet nanoscale resolution imaging of lipids has been largely limited to electron microscopy techniques. We introduce and validate a chemical tag that enables lipid membranes to be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f4fa2fa08cd52934484679cac2a0c9
Autor:
Edward S. Boyden, Adam H. Marblestone
Publikováno v:
Neuron. 102(3)
How can engineers help invent tools for neuroscience? We here explore a model for how engineers can choose problems and map out possible technologies that help address them. We also discuss design principles of tools and the role of failure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc895b5d850382b025623baeb579a98
https://pubmed.ncbi.nlm.nih.gov/31071286
https://pubmed.ncbi.nlm.nih.gov/31071286