Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Adam H Dyer"'
Autor:
Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight, Antoinette O’Connor, Adam H Dyer, Sean P Kennelly, Emily Killeen, Christine Gaffney, Helena Dolphin, Laura Morrison, Gavin Sedgwick, Aoife McFeely, Conal Gallagher, Naomi Davey, Conor Young, Ruth Ennis, Cathy McHale, Jasmine Joseph, Emmet Kelly, Nollaig M Bourke, Aoife Fallon, Sean O’Dowd
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the understanding
Externí odkaz:
https://doaj.org/article/0170f17c49d84fd19fc343b814ad8a68
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285529 (2023)
BackgroundIn addition to the clear cardiovascular benefit, there has been renewed interest in the potential of statins in the prevention of cognitive impairment and dementia in older adults. However, whether ongoing statin use can delay cognitive dec
Externí odkaz:
https://doaj.org/article/b2bd3f353dac4d388c9970b0e35d7bb9
Autor:
Liam Townsend, Adam H Dyer, Karen Jones, Jean Dunne, Aoife Mooney, Fiona Gaffney, Laura O'Connor, Deirdre Leavy, Kate O'Brien, Joanne Dowds, Jamie A Sugrue, David Hopkins, Ignacio Martin-Loeches, Cliona Ni Cheallaigh, Parthiban Nadarajan, Anne Marie McLaughlin, Nollaig M Bourke, Colm Bergin, Cliona O'Farrelly, Ciaran Bannan, Niall Conlon
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0240784 (2020)
Fatigue is a common symptom in those presenting with symptomatic COVID-19 infection. However, it is unknown if COVID-19 results in persistent fatigue in those recovered from acute infection. We examined the prevalence of fatigue in individuals recove
Externí odkaz:
https://doaj.org/article/fb5f01d27fa447eda241a1104ee834dc
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Insulin-Like Growth Factor 1 (IGF-1) is a neurotrophic polypeptide with crucial roles to play in Central Nervous System (CNS) growth, development and maturation. Following interrogation of the neurobiology underlying several neurodevelopmental disord
Externí odkaz:
https://doaj.org/article/235cfbfcbb3d4df08f4842c038e9d0d6
Autor:
Liam Townsend, Adam H. Dyer, Aifric Naughton, Sultan Imangaliyev, Jean Dunne, Rachel Kiersey, Dean Holden, Aoife Mooney, Deirdre Leavy, Katie Ridge, Jamie Sugrue, Mubarak Aldoseri, Jo Hannah Kelliher, Martina Hennessy, Declan Byrne, Paul Browne, Christopher L. Bacon, Catriona Doyle, Ruth O’Riordan, Anne-Marie McLaughlin, Ciaran Bannan, Ignacio Martin-Loeches, Arthur White, Rachel M. McLoughlin, Colm Bergin, Nollaig M. Bourke, Cliona O’Farrelly, Niall Conlon, Clíona Ní Cheallaigh
Publikováno v:
Heliyon, Vol 8, Iss 4, Pp e09230- (2022)
SARS-CoV-2 infection causes a wide spectrum of disease severity. Identifying the immunological characteristics of severe disease and the risk factors for their development are important in the management of COVID-19. This study aimed to identify and
Externí odkaz:
https://doaj.org/article/2042931142d64da28927de464f03535e
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Previous evidence suggests that slower gait speed is longitudinally associated with cognitive impairment, dementia and falls in older adults. Despite this, the longitudinal relationship between gait speed, cognition and falls in t
Externí odkaz:
https://doaj.org/article/66997f25611746c4b3112df79d1b90cc
Autor:
Pieter M. R. Herings, Adam H. Dyer, Sean P. Kennelly, Sean Reid, Isabelle Killane, Louise McKenna, Nollaig M. Bourke, Conor P. Woods, Desmond O’Neill, James Gibney, Richard B. Reilly
Publikováno v:
Sensors, Vol 22, Iss 15, p 5710 (2022)
Type 2 Diabetes Mellitus (T2DM) in midlife is associated with a greater risk of dementia in later life. Both gait speed and spatiotemporal gait characteristics have been associated with later cognitive decline in community-dwelling older adults. Thus
Externí odkaz:
https://doaj.org/article/7ed7546e4d974debad4e434247f6ac74
Autor:
Conor Keogh, Giorgio Pini, Adam H. Dyer, Stefania Bigoni, Pietro DiMarco, Ilaria Gemo, Richard Reilly, Daniela Tropea
Publikováno v:
BMC Pediatrics, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Rett Syndrome (RTT) is a complex neurodevelopmental disorder, frequently associated with epilepsy. Despite increasing recognition of the clinical heterogeneity of RTT and its variants (e.g Classical, Hanefeld and PSV(Preserved Spe
Externí odkaz:
https://doaj.org/article/ba3e86cdc53748ecabe6741a9bfcf0d4
Autor:
Adam H. Dyer, Aoife Fallon, Claire Noonan, Helena Dolphin, Cliona O’Farrelly, Nollaig M. Bourke, Desmond O’Neill, Sean P. Kennelly
Publikováno v:
Journal of the American Medical Directors Association. 23:1590-1602
Older adults in nursing homes are at greatest risk of morbidity and mortality from SARS-CoV-2 infection. Nursing home residents constituted one-third to more than half of all deaths during the early waves of the COVID-19 pandemic. Following this, wid
Autor:
Heike C. Hawerkamp, Adam H. Dyer, Neha D. Patil, Matt McElheron, Niamh O’Dowd, Laura O’Doherty, Aisling Ui Mhaonaigh, Angel M. George, Aisling M. O’Halloran, Conor Reddy, Rose Anne Kenny, Mark A. Little, Ignacio Martin-Loeches, Colm Bergin, Sean P. Kennelly, Seamas C. Donnelly, Nollaig M. Bourke, Aideen Long, Jacklyn Sui, Derek G. Doherty, Niall Conlon, Cliona Ni Cheallaigh, Padraic G. Fallon
Publikováno v:
Frontiers in Immunology. 14
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic, are remarkably variable ranging from asymptomatic infection to severe pneumonia and death. One of the key drivers of this variability is differing trajectories in t