A preclinical radiotherapy dosimetry audit using a realistic 3D printed murine phantom

Autor: Emma R. Biglin, Adam H. Aitkenhead, Gareth J. Price, Amy L. Chadwick, Elham Santina, Kaye J. Williams, Karen J. Kirkby

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Preclinical radiation research lacks standardized dosimetry procedures that provide traceability to a primary standard. Consequently, ensuring accuracy and reproducibility between studies is challenging. Using 3D printed murine phantoms we u

Externí odkaz: https://doaj.org/article/837936469b87449c8bfd74544c4248a6

Proton linear energy transfer and variable relative biological effectiveness for adolescent patients with Hodgkin lymphoma

Autor: Laura Ann Rechner, Maja V Maraldo, Edward AK Smith, Anni Y. Lundgaard, Lisa L. Hjalgrim, Ranald I. MacKay, Adam H. Aitkenhead, Marianne C. Aznar

Publikováno v: BJR|Open. 5

Objectives: Proton therapy has a theoretical dosimetric advantage due to the Bragg peak, but the linear energy transfer (LET), and therefore the relative biological effectiveness (RBE), increase at the end of range. For patients with Hodgkin lymphoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71fc8305396d1ba6316f30c0f78f386f
https://doi.org/10.1259/bjro.20230012

A preclinical radiotherapy dosimetry audit using a realistic 3D printed murine phantom

Autor: Emma R, Biglin, Adam H, Aitkenhead, Gareth J, Price, Amy L, Chadwick, Elham, Santina, Kaye J, Williams, Karen J, Kirkby

Publikováno v: Scientific reports. 12(1)

Preclinical radiation research lacks standardized dosimetry procedures that provide traceability to a primary standard. Consequently, ensuring accuracy and reproducibility between studies is challenging. Using 3D printed murine phantoms we undertook

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e595d1b327ffaf9c6252dd6fcbf3b30
https://pubmed.ncbi.nlm.nih.gov/35474242

An analysis of the origin of differences between measured and simulated fields produced by a 15-element ultrasound phased array

Autor: John A. Mills, Adrian J. Wilson, Adam H. Aitkenhead

Publikováno v: Ultrasound in medicinebiology. 36(3)

Modeling provides an attractive approach for the design of phased array ultrasound transducers for hyperthermia. However, measurements on physical transducers reveal differences from the idealized field profiles predicted by simulation. In this paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed88eb69ff7a5a39cc2a55081e18d55
https://pubmed.ncbi.nlm.nih.gov/20133041

Estimating the percentage of patients who might benefit from proton beam therapy instead of X-ray radiotherapy

Autor: Neil G Burnet, Thomas Mee, Simona Gaito, Norman F Kirkby, Adam H Aitkenhead, Carmel N Anandadas, Marianne C Aznar, Lisa H Barraclough, Gerben Borst, Frances C Charlwood, Matthew Clarke, Rovel J Colaco, Adrian M Crellin, Noemie N Defourney, Christina J Hague, Margaret Harris, Nicholas T Henthorn, Kirsten I Hopkins, E Hwang, Sam P Ingram, Karen J Kirkby, Lip W Lee, David Lines, Zoe Lingard, Matthew Lowe, Ranald I Mackay, Catherine A McBain, Michael J Merchant, David J Noble, Shermaine Pan, James M Price, Ganesh Radhakrishna, David Reboredo-Gil, Ahmed Salem, Srijith Sashidharan, Peter Sitch, Ed Smith, Edward AK Smith, Michael J Taylor, David J Thomson, Nicola J Thorp, Tracy SA Underwood, John W Warmenhoven, James P Wylie, Gillian Whitfield

Publikováno v: Burnet, N G, Mee, T, Gaito, S, Kirkby, N F, Aitkenhead, A H, Anandadas, C N, Aznar, M C, Barraclough, L H, Borst, G, Charlwood, F C, Clarke, M, Colaco, R J, Crellin, A M, Defourney, N N, Hague, C J, Harris, M, Henthorn, N T, Hopkins, K I, Hwang, E, Ingram, S P, Kirkby, K J, Lee, L W, Lines, D, Lingard, Z, Lowe, M, Mackay, R I, McBain, C A, Merchant, M J, Noble, D J, Pan, S, Price, J M, Radhakrishna, G, Reboredo-Gil, D, Salem, A, Sashidharan, S, Sitch, P, Smith, E, Smith, E A, Taylor, M J, Thomson, D J, Thorp, N J, Underwood, T S, Warmenhoven, J W, Wylie, J P & Whitfield, G 2022, ' Estimating the percentage of patients who might benefit from proton beam therapy instead of X-ray radiotherapy ', The British journal of radiology, vol. 95, no. 1133, A5, pp. 20211175 . https://doi.org/10.1259/bjr.20211175

Objectives: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We sought expert opinion on the level of provision. Methods: Invitations were sent to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07dd145358515d081f5c83c99768105