Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adam Gulbranson-Judge"'
Autor:
Mahmood Khan, Adam Gulbranson-Judge, Michael John Owen, Ian C. M. MacLennan, Carola G. Vinuesa, Matthias Wabl, Gerry G. B. Klaus, Paula O’Leary, Marilia Cascalho
Publikováno v:
European Journal of Immunology. 29:3712-3721
A subset of myeloid dendritic cells is described which is associated with the ability of splenic and lymph node plasmablasts to survive and differentiate into plasma cells. Plasmablast-associated dendritic cells (PDC) are CD11c(high), DEC-205(-) and
Autor:
Kai-Michael Toellner, Martin R Turner, Ian C. M. MacLennan, Victor L. J. Tybulewicz, Adam Gulbranson-Judge, Alice E. Walters
Publikováno v:
European Journal of Immunology. 29:477-487
Vav, a guanine nucleotide exchange factor for members of the Rho family of small GTPases, is activated through engagement of B and T lymphocyte antigen receptors. It is important for establishing the signaling threshold of the TCR, as mice lacking Va
Publikováno v:
Annals of the New York Academy of Sciences. 815:199-210
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 185, no. 3, pp. 551-562
Journal of Experimental Medicine, vol. 185, no. 3, pp. 551-562
Mouse mammary tumor virus (MMTV[SW]) encodes a superantigen expressed by infected B cells. It evokes an antibody response specific for viral envelope protein, indicating selective activation of antigen-specific B cells. The response to MMTV(SW) in dr
Autor:
Adam Gulbranson-Judge, William Pao, Adrian Hayday, Ian C. M. MacLennan, Michael John Owen, Biao Zheng, Garnett Kelsoe, Li Wen, Adrian Smith
Publikováno v:
Current Biology. 6(10):1317-1325
gamma delta T cells, like alpha beta T cells, are components of all well-studied vertebrate immune systems. Yet, the contribution of gamma delta T cells to immune responses is poorly characterized. In particular, it has not been resolved whether gamm
Autor:
Adam Gulbranson-Judge, William Pao, Adrian Hayday, Lee Dianda, Ian C. M. MacLennan, Michael John Owen
Publikováno v:
European Journal of Immunology. 26:1603-1607
T cells are essential for inducing clonal B cell expansion in germinal centers during T cell-dependent antibody responses. However, class-switched antibodies are readily detectable in TCR alpha-deficient mice that congenitally lack alpha beta T cells
Autor:
Margaret Goodall, Fabrina Gaspal, Fiona M. McConnell, Adam Gulbranson-Judge, Peter J. L. Lane, Chandra Raykundalia, Mi-Yeon Kim, Helen E. Wiggett, Lucy S. K. Walker
Publikováno v:
Immunity. 18(5)
In this report we identify an accessory cell that interacts with primed and memory T cells at sites where they collaborate with B cells. These cells are distinguished from conventional dendritic cells by their lack of response to Flt3 ligand and thei
Publikováno v:
Immunology today. 21(7)
Given the importance of responding to infections with the right defensive strategy, much interest has focused on cytokine differentiation in CD4+ T cells. However, relatively little is known of the logistics of T-cell help for B cells. Here, Lucy Wal
Autor:
Sarah Flynn, Peter J. L. Lane, Chandra Raykundalia, Mireille Riedinger, Thomas Brocker, Adam Gulbranson-Judge
Publikováno v:
European journal of immunology. 29(5)
We report here that CD40- but not lipopolysaccharide (LPS)-activated murine dendritic cells (DC) express OX40-ligand (OX40L) as has been reported in humans. To understand how OX40 ligation affects differentiation of CD4 T cells at the time of priming
Autor:
Victor L. J. Tybulewicz, Adam Gulbranson-Judge, Martin R Turner, Alice E. Walters, Marian E. Quinn, Ian C. M. MacLennan
Publikováno v:
The Journal of Experimental Medicine
The tyrosine kinase Syk has been implicated as a key signal transducer from the B cell antigen receptor (BCR). We show here that mutation of the Syk gene completely blocks the maturation of immature B cells into recirculating cells and stops their en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184c0297c8c93e326d39036db3c10e72
http://hdl.handle.net/10044/1/58000
http://hdl.handle.net/10044/1/58000