Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Adam Grippin"'
Autor:
Christina A. von Roemeling, Jeet A. Patel, Savannah L. Carpenter, Oleg Yegorov, Changlin Yang, Alisha Bhatia, Bently P. Doonan, Rylynn Russell, Vrunda S. Trivedi, Kelena Klippel, Daniel H. Ryu, Adam Grippin, Hunter S. Futch, Yong Ran, Lan B. Hoang-Minh, Frances L. Weidert, Todd E. Golde, Duane A. Mitchell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract There are numerous mechanisms by which glioblastoma cells evade immunological detection, underscoring the need for strategic combinatorial treatments to achieve appreciable therapeutic effects. However, developing combination therapies is di
Externí odkaz:
https://doaj.org/article/bc9016cb7fb14ca0b35b39a6afc4265c
Autor:
Duane A Mitchell, John A Ligon, Duy Nguyen, Paul Castillo, Natalie Silver, W Gregory Sawyer, Brian Stover, Frances Weidert, Adam Grippin, Lana Fagman, Jonathan Chardon-Robles, Gabriel Jobin, Chao Xie, Nicholas Diodati, Joanne Lagmay, Leighton Elliott, Eugene Hwang, Michael Isakoff, Lars Wagner, Rowan Milner, Hector Mendez-Gomez, Study Staff, Elias Sayour
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/529c96b798754d6a8ad8afeae3e9597a
Autor:
John A Ligon, Paul Castillo, Christina Von Roemeling, Natalie Silver, Frances Weidert, Adam Grippin, Jonathan Chardon-Robles, Eugene Hwang, Hector Mendez-Gomez, Study Staff, Elias Sayour, Sadeem Qdaisat, Dingpeng Zhang, James McGuiness, Nagheme Thomas, Anna Devries, Aida Karachi, Jianping Huang, Maryam Rahman, Elizabeth Ogando-Rivas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff4cba9d8a244bf78c4d8b10af09b189
Autor:
Olsi Gjyshi, Adam Grippin, Lauren Andring, Anuja Jhingran, Lilie L. Lin, Julianna Bronk, Patricia J. Eifel, Melissa M. Joyner, Jagannadha K. Sastry, Kyoko Yoshida-Court, Travis N. Solley, Tatiana Cisneros Napravnik, Madison P. O'Hara, Venkatesh L Hegde, Lauren E. Colbert, Ann H Klopp
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 39, Iss , Pp 100578- (2023)
Purpose: The immune system’s role in mediating the cytotoxic effects of chemoradiotherapy remains not completely understood. The integration of immunotherapies into treatment will require insight into features and timing of the immune microenvironm
Externí odkaz:
https://doaj.org/article/7f3ed66fbc544424af486805649d57a8
Autor:
Kyle A. Dyson, Brian D. Stover, Adam Grippin, Hector R. Mendez-Gomez, Joanne Lagmay, Duane A. Mitchell, Elias J. Sayour
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract While promising, immunotherapy has yet to be fully unlocked for the preponderance of cancers where conventional chemoradiation reigns. This remains particularly evident in pediatric sarcomas where standard of care has not appreciably changed
Externí odkaz:
https://doaj.org/article/7c547a759aa04abf906ac9bba7586741
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 9-9 (2017)
OBJECTIVES/SPECIFIC AIMS: Immune-based therapies hold great promise for treatment of refractory tumors. However, development is limited by a lack of identified immune correlates to vaccination. We recently showed that dendritic cells (DCs) prolong pr
Externí odkaz:
https://doaj.org/article/eee89cc6c04c418b90cc93e7eae78625
Autor:
Duane A. Mitchell, Catherine T. Flores, Rebecca S. Abraham, David J. Damiani, Brandon M. Wummer, Kyle A. Dyson, Adam Grippin, Tyler J. Wildes
HSPC-derived DCs generated in vitro display DC phenotype and function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae9daebe66d307a032297afc16b9523
https://doi.org/10.1158/1078-0432.22467894.v1
https://doi.org/10.1158/1078-0432.22467894.v1
Autor:
Duane A. Mitchell, Catherine T. Flores, Rebecca S. Abraham, David J. Damiani, Brandon M. Wummer, Kyle A. Dyson, Adam Grippin, Tyler J. Wildes
T cell recognition of cognate antigen drives release of soluble factors including IFN-g and GM-CSF. T cell-released IFN-g and GM-CSF contribute to HSPC differentiation. Supernatant transfer with cytokine knockout T cells differentiates the roles of I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2747761a04b4b100cae79744dd0fe0b5
https://doi.org/10.1158/1078-0432.22467888.v1
https://doi.org/10.1158/1078-0432.22467888.v1
Autor:
Catherine T. Flores, Duane A. Mitchell, Carmelle Kuizon, Ginger Moore, Christina Pham, Rebecca Abraham, Bayli DiVita Dean, Adam Grippin, David Shin, Oleg Yegorov, Changlin Yang, Brandon Wummer, Connor Francis, Kyle A. Dyson, Tyler J. Wildes
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b273cfa02cc2cddc9347f1f4816d5d
https://doi.org/10.1158/1078-0432.22476854.v1
https://doi.org/10.1158/1078-0432.22476854.v1
Autor:
Duane A. Mitchell, Catherine T. Flores, Rebecca S. Abraham, David J. Damiani, Brandon M. Wummer, Kyle A. Dyson, Adam Grippin, Tyler J. Wildes
Purpose: Adoptive T-cell immunotherapy (ACT) has emerged as a viable therapeutic for peripheral and central nervous system (CNS) tumors. In peripheral cancers, optimal efficacy of ACT is reliant on dendritic cells (DCs) in the tumor microenvironment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ce4f868f462869f7c96fda80e032a7
https://doi.org/10.1158/1078-0432.c.6526770.v1
https://doi.org/10.1158/1078-0432.c.6526770.v1