Zobrazeno 1 - 10 of 76 pro vyhledávání: '"Adam Greenstein"'
2
Akademický článek
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia
Autor: Sarmi Sri, Adam Greenstein, Alessandra Granata, Alex Collcutt, Angela C C Jochems, Barry W McColl, Blanca Díaz Castro, Caleb Webber, Carmen Arteaga Reyes, Catherine Hall, Catherine B Lawrence, Cheryl Hawkes, Chrysia-Maria Pegasiou-Davies, Claire Gibson, Colin L Crawford, Colin Smith, Denis Vivien, Fiona H McLean, Frances Wiseman, Gaia Brezzo, Giovanna Lalli, Harry A T Pritchard, Hugh S Markus, Isabel Bravo-Ferrer, Jade Taylor, James Leiper, Jason Berwick, Jian Gan, John Gallacher, Jonathan Moss, Jozien Goense, Letitia McMullan, Lorraine Work, Lowri Evans, Michael S Stringer, MLJ Ashford, Mohamed Abulfadl, Nina Conlon, Paresh Malhotra, Philip Bath, Rebecca Canter, Rosalind Brown, Selvi Ince, Silvia Anderle, Simon Young, Sophie Quick, Stefan Szymkowiak, Steve Hill, Stuart Allan, Tao Wang, Terry Quinn, Tessa Procter, Tracy D Farr, Xiangjun Zhao, Zhiyuan Yang, Atticus H Hainsworth, Joanna M Wardlaw
Publikováno v: Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100189- (2023)
Although dementia research has been dominated by Alzheimer's disease (AD), most dementia in older people is now recognised to be due to mixed pathologies, usually combining vascular and AD brain pathology. Vascular cognitive impairment (VCI), which e
Externí odkaz: https://doaj.org/article/9ffe49ccbd5b476183d732a9dab4e59d
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3
Akademický článek
Engaging parents using web-based feedback on child growth to reduce childhood obesity: a mixed methods study
Autor: Rinita Dam, Heather Anne Robinson, Sarah Vince-Cain, Gill Heaton, Adam Greenstein, Matthew Sperrin, Lamiece Hassan
Publikováno v: BMC Public Health, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background To measure trends in child growth and combat rising levels of obesity, Manchester University NHS Foundation Trust and the University of Manchester have developed Children’s Health and Monitoring Programme (CHAMP). CHAMP collects
Externí odkaz: https://doaj.org/article/52f07eedfae74c728353083aff339fba
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4
Akademický článek
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response
Autor: Jenna Scotcher, Oleksandra Prysyazhna, Andrii Boguslavskyi, Kornel Kistamas, Natasha Hadgraft, Eva D. Martin, Jenny Worthington, Olena Rudyk, Pedro Rodriguez Cutillas, Friederike Cuello, Michael J. Shattock, Michael S. Marber, Maria R. Conte, Adam Greenstein, David J. Greensmith, Luigi Venetucci, John F. Timms, Philip Eaton
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The stroke volume of the heart increases in response to an increase in the blood volume filling the heart. Here the authors reveal that this coordinated process is mediated in part by oxidative activation of the protein kinase G Iα, which phosphoryl
Externí odkaz: https://doaj.org/article/03ace94ba067478fa8463d2ab1ace41b
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5
BK channel dysfunction underlies small vessel disease of the brain in both hypertension and Alzheimer's disease
Autor: Katy Walsh, Jade Taylor, Thea Danby, Grant Hennig, Stuart Allan, Mark Nelson, Harry Pritchard, Adam Greenstein
Publikováno v: Physiology. 38
Alzheimer's disease (AD) and hypertension-related vascular dementia share many common clinical and radiological features including cerebral small vessel disease (cSVD) of the brain, thought to be the mechanism behind the reduction in cerebral blood f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::111d87bcc93fb958859357df9d4a719d
https://doi.org/10.1152/physiol.2023.38.s1.5730991
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6
Oxidant activation of endothelial PKG regulates TRPV4-mediated vasodilation in mesenteric and pulmonary resistance arteries
Autor: Hala Alhabashneh, Sharifah Abdul Kadir, Harry Pritchard, Adam Greenstein, Alison Gurney
Publikováno v: Physiology. 38
Smooth muscle protein kinase G (PKG) mediates vasodilation whether activated by the NO/cGMP signalling pathway or by oxidation of cysteine residues in the PKGIα subunit1. PKG is also present in endothelial cells, where it is proposed to inhibit Ca2+
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2494c7fda1abdaf5693cc6f87fd5ea8c
https://doi.org/10.1152/physiol.2023.38.s1.5731518
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7
Macro- and Microvascular Function in Middle-Aged Individuals with Low Cardiovascular Disease Risk
Autor: Sunni Patel, Hala Shokr, Adam Greenstein, Doina Gherghel
Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 23; Pages: 6962
Patel, S, Shokr, H, Greenstein, A & Gherghel, D 2022, ' Macro-and Microvascular Function in Middle-Aged Individuals with Low Cardiovascular Disease Risk ', Journal of Clinical Medicine, vol. 11, no. 23, 6962 . https://doi.org/10.3390/jcm11236962
Aims: To investigate the microvascular function in apparently healthy individuals showing signs of early macrovascular endothelial dysfunction. Methods: Healthy participants aged between 30–55 years were recruited for the present study. Baseline me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4d14d06aad557d3b4a32a27eb9f542
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