Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Adam G West"'
Autor:
Hannah Donnelly, Ewan Ross, Yinbo Xiao, Rio Hermantara, Aqeel F. Taqi, W. Sebastian Doherty-Boyd, Jennifer Cassels, Penelope. M. Tsimbouri, Karen M. Dunn, Jodie Hay, Annie Cheng, R. M. Dominic Meek, Nikhil Jain, Christopher West, Helen Wheadon, Alison M. Michie, Bruno Peault, Adam G. West, Manuel Salmeron-Sanchez, Matthew J. Dalby
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Long-term reconstituting haematopoietic stem cells (LT-HSCs) are used to treat blood disorders via stem cell transplantation. The very low abundance of LT-HSCs and their rapid differentiation during in vitro culture hinders their clinical ut
Externí odkaz:
https://doaj.org/article/e8984c0b474a49c1b8fa3b60f306f23a
Autor:
Vahideh Hassan-Zadeh, Sabarinadh Chilaka, Jean-Charles Cadoret, Meiji Kit-Wan Ma, Nicole Boggetto, Adam G West, Marie-Noëlle Prioleau
Publikováno v:
PLoS Biology, Vol 10, Iss 3, p e1001277 (2012)
The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating. GC-rich regions are gene dense and are enriched for active tr
Externí odkaz:
https://doaj.org/article/685fc0adbe6a4773aa25fada22ba7570
Autor:
Meesbah Jiwaji, Rónán Daly, Abdullah Gibriel, Gráinne Barkess, Pauline McLean, Jingli Yang, Kshama Pansare, Sarah Cumming, Alisha McLauchlan, Piotr J Kamola, Musab S Bhutta, Adam G West, Katherine L West, Walter Kolch, Mark A Girolami, Andrew R Pitt
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50521 (2012)
In recent years much progress has been made in the development of tools for systems biology to study the levels of mRNA and protein, and their interactions within cells. However, few multiplexed methodologies are available to study cell signalling di
Externí odkaz:
https://doaj.org/article/b51b65aabb0b4effa3a0670b0f43cb99
Publikováno v:
PLoS Genetics, Vol 7, Iss 7, p e1002175 (2011)
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation. The maintenance of chromatin domain integrity can require the setting
Externí odkaz:
https://doaj.org/article/15b37b97e196453a98e3f89a65880e81
Autor:
Jacqueline Dickson, Humaira Gowher, Ruslan Strogantsev, Miklos Gaszner, Alan Hair, Gary Felsenfeld, Adam G West
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000804 (2010)
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states. Chromatin insulator or barrier elements are key components of these processes
Externí odkaz:
https://doaj.org/article/39dbccdbc4e343b4923ed8cdbf91d599
Publikováno v:
Oecologia, vol 201, iss 2
Understanding climate change impacts on the Cape Floristic Region requires improved knowledge of plant physiological responses to the environment. Studies examining physiological responses of mountain fynbos have consisted of campaign-based measureme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4b46f55202ba5ee6ac05ee9b874f1f
https://escholarship.org/uc/item/43b753qm
https://escholarship.org/uc/item/43b753qm
Publikováno v:
New Phytologist. 230:1407-1420
Growth plasticity may allow fire-prone species to maximize their recovery rates during temporary, sporadic periods of rainfall availability in the post-fire environment. However, moisture-driven growth plasticity could be maladaptive in nutrient-limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fae2f44aea9cc1fbe7ab425622f7c7e
https://doi.org/10.1111/nph.17246
https://doi.org/10.1111/nph.17246
Autor:
Hannah Donnelly, Ewan Ross, Yinbo Xiao, Rio Hermantara, Aqeel Taqi, Annie Cheng, Nikhil Jain, Christopher West, Bruno Peault, Adam G. West, Manuel Salmeron-Sanchez, Matthew J. Dalby
Long-term reconstituting haematopoietic stem cells (LT-HSCs) are used to treat blood disorders via allogeneic stem cell transplantation (alloSCT), to engraft and repopulate the blood system. The very low abundance of LT-HSCs and their rapid different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b58b7fce19cf266eafda738e17344c
https://doi.org/10.1101/2022.07.28.501818
https://doi.org/10.1101/2022.07.28.501818
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Stable isotope ratios of hydrogen and oxygen (δ2H and δ18O) in tap water provide important insights into the way that people interact with and manage the hydrological cycle. Understanding how these interactions vary through space and time allows fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52eaa04c6a4efc3f930d28d041d6eca
https://doi.org/10.1038/s41598-020-70317-2
https://doi.org/10.1038/s41598-020-70317-2
Publikováno v:
Scientific Reports
Stable isotope ratios of hydrogen and oxygen (δ2H and δ18O) in tap water provide important insights into the way that people interact with and manage the hydrological cycle. Understanding how these interactions vary through space and time allows fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40dea795c66e998a2fe36794225131e8
https://pubmed.ncbi.nlm.nih.gov/32782259
https://pubmed.ncbi.nlm.nih.gov/32782259