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The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of Mycobacterium tuberculosis as Determined in a Hollow-Fiber Infection Model

Autor: G. L. Drusano, Nicole Sgambati, Adam Eichas, David L. Brown, Robert Kulawy, Arnold Louie

Publikováno v: mBio, Vol 1, Iss 3 (2010)

ABSTRACT Moxifloxacin is under development for expanded use against Mycobacterium tuberculosis. Rifampin is a mainstay of therapy. We examined the interaction of moxifloxacin plus rifampin for log-phase and nonreplicating persister (NRP) organisms. F

Externí odkaz: https://doaj.org/article/346a155c92eb441da601c67a03e408da

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The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of Mycobacterium tuberculosis as Determined in a Hollow-Fiber Infection Model

Autor: David L. Brown, Arnold Louie, Robert Kulawy, Nicole Sgambati, George L. Drusano, Adam Eichas

Publikováno v: mBio, Vol 1, Iss 3 (2010)
mBio

Moxifloxacin is under development for expanded use against Mycobacterium tuberculosis. Rifampin is a mainstay of therapy. We examined the interaction of moxifloxacin plus rifampin for log-phase and nonreplicating persister (NRP) organisms. For this e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b833c3006d1441fa3e4069ab82cb04
https://journals.asm.org/doi/10.1128/mBio.00139-10

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