Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adam Eckburg"'
Autor:
Chike Osude, Leo Lin, Meet Patel, Adam Eckburg, Joseph Berei, Adijan Kuckovic, Namrata Dube, Aayush Rastogi, Shruti Gautam, Thomas J. Smith, Shylendra B. Sreenivassappa, Neelu Puri
Publikováno v:
Cells, Vol 11, Iss 10, p 1694 (2022)
NSCLC treatment includes targeting of EGFR with tyrosine kinase inhibitors (TKIs) such as Erlotinib; however, resistance to TKIs is commonly acquired through T790M EGFR mutations or overexpression of vascular endothelial growth factor receptor-2 (VEG
Externí odkaz:
https://doaj.org/article/aa83e90141d14f91a0783e80526c33ad
Autor:
Zachary D Crees, Caleb Shearrow, Leo Lin, Jennifer Girard, Kavin Arasi, Aayush Bhoraskar, Joseph Berei, Adam Eckburg, Austin D. Anderson, Christian Garcia, Ariana Munger, Sunil Palani, Thomas J Smith, Shylendra B Sreenivassappa, Connie Vitali, Odile David, Neelu Puri
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: EGFR/c-Met activation/amplification and co-expression, mTOR upregulation/activation, and Akt/Wnt signaling upregulation have been individually associated with more aggressive disease and characterized as potential prognostic markers for l
Externí odkaz:
https://doaj.org/article/8c227a1782da4256ae9803b9ba799ade
Autor:
Taylor Rager, Adam Eckburg, Meet Patel, Rong Qiu, Shahina Gantiwala, Katrina Dovalovsky, Kelly Fan, Katie Lam, Claire Roesler, Aayush Rastogi, Shruti Gautam, Namrata Dube, Bridget Morgan, S M Nasifuzzaman, Dhruv Ramaswami, Varun Gnanasekar, Jeffrey Smith, Aftab Merchant, Neelu Puri
Publikováno v:
Cancers. 14:3779
Melanoma possesses invasive metastatic growth patterns and is one of the most aggressive types of skin cancer. In 2021, it is estimated that 7180 deaths were attributed to melanoma in the United States alone. Once melanoma metastasizes, traditional t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44eec643891b4e0fa657d02ead0daa1
https://doi.org/10.3390/cancers14153779
https://doi.org/10.3390/cancers14153779
Publikováno v:
Journal of Clinical Oncology. 40:2032-2032
2032 Background: Next-generation sequencing (NGS) of cancer specimens is a valuable diagnostic tool that can provide detailed information regarding specific somatic genetic alterations within a tumor with potential for targeted treatment. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e89696132ccfccc932107ac215c1368
https://doi.org/10.1200/jco.2022.40.16_suppl.2032
https://doi.org/10.1200/jco.2022.40.16_suppl.2032
Autor:
Odile David, Zachary Crees, Austin D. Anderson, Kavin Arasi, Ariana Munger, Lin Leo S, Caleb Shearrow, Christian Garcia, Thomas J. Smith, Neelu Puri, Shylendra Sreenivassappa, Aayush Bhoraskar, Sunil Palani, Jennifer Girard, Adam Eckburg, Connie Vitali, Joseph Berei
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background:EGFR/c-Met activation/amplification and co-expression, mTOR upregulation/activation, and Akt/Wnt signaling upregulation have been individually associated with more aggressive disease and characterized as potential prognostic markers for lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c168ed28adc5c8b745194be9d014cec6
https://doaj.org/article/8c227a1782da4256ae9803b9ba799ade
https://doaj.org/article/8c227a1782da4256ae9803b9ba799ade
Autor:
Kavya Sri Racherla, Joseph Berei, Allison M. Giuffre, Austin D. Anderson, Meet Patel, Monica Saravana Vela, Adam Eckburg, Neelu Puri, Diana Tang, Joshua Dein, Rachel J. Miller, Edward Miliavski, Shreya Deb
Publikováno v:
Current topics in medicinal chemistry. 20(6)
Telomeres function as protective caps at the terminal portion of chromosomes, containing non-coding nucleotide sequence repeats. As part of their protective function, telomeres preserve genomic integrity and minimize chromosomal exposure, thus limiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f4ac8620b3d7913f2709a11b6f7e2e
https://pubmed.ncbi.nlm.nih.gov/31916516
https://pubmed.ncbi.nlm.nih.gov/31916516
Autor:
Joshua Dein, Adam Eckburg, Zachary Hart, Neelu Puri, Shahina Gantiwala, Katie Lam, Meet Patel
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1115, p 1115 (2021)
Cancers, Vol 13, Iss 1115, p 1115 (2021)
Simple Summary Metastatic melanoma has poor survival rates in comparison to other types of skin cancer. Traditional therapies are not very effective in treating advanced melanoma. For this reason, several molecular targeted therapies such as tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4cea57d3a1b28f7b516fde91894760
https://doi.org/10.3390/cancers13051115
https://doi.org/10.3390/cancers13051115
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2337, p 2337 (2020)
Cancers, Vol 12, Iss 2337, p 2337 (2020)
Telomerase provides cancer cells with replicative immortality, and its overexpression serves as a near-universal marker of cancer. Anti-cancer therapeutics targeting telomerase have garnered interest as possible alternatives to chemotherapy and radio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcd97797edc947f0fa1713c59d2afdc
https://doi.org/10.3390/cancers12092337
https://doi.org/10.3390/cancers12092337