Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Adam Dewan"'
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298448 (2024)
Monoterpenes are a large class of naturally occurring fragrant molecules. These chemicals are commonly used in olfactory studies to survey neural activity and probe the behavioral limits of odor discrimination. Monoterpenes (typically in the form of
Externí odkaz:
https://doaj.org/article/43a77f37af90490cae435e6d05386207
Autor:
Adam Dewan, Annika Cichy, Jingji Zhang, Kayla Miguel, Paul Feinstein, Dmitry Rinberg, Thomas Bozza
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Odorous chemicals broadly activate subsets of olfactory receptors in the nose, but how individual receptors contribute to behavioral sensitivity is not clear. Here, the authors demonstrate that detection thresholds in mice are set solely by the highe
Externí odkaz:
https://doaj.org/article/919ce589a86f4f4b8f1ee4be45132f62
Publikováno v:
Cell Reports, Vol 2, Iss 1, Pp 76-88 (2012)
Olfactory stimuli are detected by over 1,000 odorant receptors in mice, with each receptor being mapped to specific glomeruli in the olfactory bulb. The trace amine-associated receptors (TAARs) are a small family of evolutionarily conserved olfactory
Externí odkaz:
https://doaj.org/article/7592ad31164d43bc95f5d11f8963869e
Autor:
Samuel Caton, Adam Dewan
Publikováno v:
Current Biology. 33:R311-R313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f90234e1d4386b6b964ce6b0fb8f83
https://doi.org/10.1016/j.cub.2023.03.046
https://doi.org/10.1016/j.cub.2023.03.046
Publikováno v:
Chem Senses
Olfactory studies frequently utilize odor stimuli consisting of volatiles created from liquid dilutions of various chemicals. A problem arises if the researcher relies on these liquid dilutions to extrapolate vapor concentrations based on ideal gas b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26148e1047019a06d6b7fe3242fd3f6
https://pubmed.ncbi.nlm.nih.gov/36571813
https://pubmed.ncbi.nlm.nih.gov/36571813
Publikováno v:
Chemical senses. 47
Measures of behavioral sensitivity provide an important guide for choosing the stimulus concentrations used in functional experiments. This information is particularly valuable in the olfactory system as the neural representation of an odorant change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc021ce205475382aa27bff50c49d90e
https://pubmed.ncbi.nlm.nih.gov/35816188
https://pubmed.ncbi.nlm.nih.gov/35816188
Autor:
Adam Dewan
Publikováno v:
Cell Tissue Res
Trace Amine-Associated Receptors (TAARs) are a family of G protein-coupled receptors that function as odorant receptors in the main olfactory system of vertebrates. TAARs are monoallelically expressed in primary sensory neurons where they couple to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82dcd6a86beecdc2c6b4bdbb0a7fd9d
https://doi.org/10.1007/s00441-020-03331-5
https://doi.org/10.1007/s00441-020-03331-5
Autor:
Ellie Williams, Adam Dewan
Publikováno v:
Chemical Senses
Probing the neural mechanisms that underlie each sensory system requires the presentation of perceptually appropriate stimulus concentrations. This is particularly relevant in the olfactory system as additional odorant receptors typically respond wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bb034badae08502bfeb82c5d709181
https://doi.org/10.1093/chemse/bjaa045
https://doi.org/10.1093/chemse/bjaa045
Autor:
Annika Cichy, Adam Dewan, Jingji Zhang, Sarah Kaye, Tiffany Teng, Kassandra Blanchard, Paul Feinstein, Thomas Bozza
While the olfactory system is required for proper social behaviors, the molecular basis for how social cues are detected via the main olfactory pathway of mammals is not well-characterized. Trimethylamine is a volatile, sex-specific odor found in adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c290e86b779e44ecd0e3e0df580e7bd1
https://doi.org/10.1101/2021.12.30.474554
https://doi.org/10.1101/2021.12.30.474554
Autor:
Vincenzo F. Curto, Erez Shor, Ilke Uguz, George G. Malliaras, Adam Dewan, Thomas Bozza, Cristina Savin, Pedro Herrero-Vidal, Dmitry Rinberg
Publikováno v:
Biosensorsbioelectronics. 195
When it comes to detecting volatile chemicals, biological olfactory systems far outperform all artificial chemical detection devices in their versatility, speed, and specificity. Consequently, the use of trained animals for chemical detection in secu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdaa08b9923cd41f8c7f6aab95efe51
https://pubmed.ncbi.nlm.nih.gov/34624799
https://pubmed.ncbi.nlm.nih.gov/34624799