Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Adam Denes"'
Autor:
Kinga Gecse, Andrea Edit Édes, Tamás Nagy, Adrienn Katalin Demeter, Dávid Virág, Márton Király, Borbála Dalmadi Kiss, Krisztina Ludányi, Zsuzsanna Környei, Adam Denes, Gyorgy Bagdy, Gabriella Juhasz
Publikováno v:
Cells, Vol 11, Iss 14, p 2258 (2022)
Altered tryptophan (TRP) metabolism may have an important role in migraine susceptibility through its main metabolites, serotonin and kynurenine (KYN). Both affect pain processing and stress response by interfering with neural and brain hypersensitiv
Externí odkaz:
https://doaj.org/article/d9aec836ac3e4c959d6846a3073f5f3a
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 1043-1048 (2013)
SUMMARY Interleukin-1 (IL-1) is a key regulator of inflammation and ischaemic brain injury, but the contribution of central and peripheral sources of IL-1 to brain injury is not well understood. Here we show that haematopoietic-derived IL-1 is a key
Externí odkaz:
https://doaj.org/article/6bb44942c88c4069b78416c633deeb83
Autor:
Cserép, Csaba, Schwarcz, Anett D., Pósfai, Balázs, László, Zsófia I., Kellermayer, Anna, Környei, Zsuzsanna, Kisfali, Máté, Nyerges, Miklós, Lele, Zsolt, Katona, István, Ádám Dénes
Publikováno v:
In Cell Reports 20 September 2022 40(12)
Autor:
Rosa C. Paolicelli, Amanda Sierra, Beth Stevens, Marie-Eve Tremblay, Adriano Aguzzi, Bahareh Ajami, Ido Amit, Etienne Audinat, Ingo Bechmann, Mariko Bennett, Frederick Bennett, Alain Bessis, Knut Biber, Staci Bilbo, Mathew Blurton-Jones, Erik Boddeke, Dora Brites, Bert Brône, Guy C. Brown, Oleg Butovsky, Monica J. Carson, Bernardo Castellano, Marco Colonna, Sally A. Cowley, Colm Cunningham, Dimitrios Davalos, Philip L. De Jager, Bart de Strooper, Adam Denes, Bart J.L. Eggen, Ukpong Eyo, Elena Galea, Sonia Garel, Florent Ginhoux, Christopher K. Glass, Ozgun Gokce, Diego Gomez-Nicola, Berta González, Siamon Gordon, Manuel B. Graeber, Andrew D. Greenhalgh, Pierre Gressens, Melanie Greter, David H. Gutmann, Christian Haass, Michael T. Heneka, Frank L. Heppner, Soyon Hong, David A. Hume, Steffen Jung, Helmut Kettenmann, Jonathan Kipnis, Ryuta Koyama, Greg Lemke, Marina Lynch, Ania Majewska, Marzia Malcangio, Tarja Malm, Renzo Mancuso, Takahiro Masuda, Michela Matteoli, Barry W. McColl, Veronique E. Miron, Anna Victoria Molofsky, Michelle Monje, Eva Mracsko, Agnes Nadjar, Jonas J. Neher, Urte Neniskyte, Harald Neumann, Mami Noda, Bo Peng, Francesca Peri, V. Hugh Perry, Phillip G. Popovich, Clare Pridans, Josef Priller, Marco Prinz, Davide Ragozzino, Richard M. Ransohoff, Michael W. Salter, Anne Schaefer, Dorothy P. Schafer, Michal Schwartz, Mikael Simons, Cody J. Smith, Wolfgang J. Streit, Tuan Leng Tay, Li-Huei Tsai, Alexei Verkhratsky, Rommy von Bernhardi, Hiroaki Wake, Valérie Wittamer, Susanne A. Wolf, Long-Jun Wu, Tony Wyss-Coray
Publikováno v:
Neuron
Neuron, vol 110, iss 21
Paolicelli, R C, Sierra, A, Stevens, B, Tremblay, M-E, Aguzzi, A, Ajami, B, Amit, I, Audinat, E, Bechmann, I, Bennett, M, Bennett, F, Bessis, A, Biber, K, Bilbo, S, Blurton-Jones, M, Boddeke, E, Brites, D, Brône, B, Brown, G C, Butovsky, O, Carson, M J, Castellano, B, Colonna, M, Cowley, S A, Cunningham, C, Davalos, D, de Jager, P L, de Strooper, B, Denes, A, Eggen, B J L, Eyo, U, Galea, E, Garel, S, Ginhoux, F, Glass, C K, Gokce, O, Gomez-Nicola, D, González, B, Gordon, S, Graeber, M B, Greenhalgh, A D, Gressens, P, Greter, M, Gutmann, D H, Haass, C, Heneka, M T, Heppner, F L, Hong, S, Hume, D A, Jung, S, Kettenmann, H, Kipnis, J, Koyama, R, Lemke, G, Lynch, M, Majewska, A, Malcangio, M, Malm, T, Mancuso, R, Masuda, T, Matteoli, M, McColl, B W, Miron, V E, Molofsky, A V, Monje, M, Mracsko, E, Nadjar, A, Neher, J J, Neniskyte, U, Neumann, H, Noda, M, Peng, B, Peri, F, Perry, V H, Popovich, P G, Pridans, C, Priller, J, Prinz, M, Ragozzino, D, Ransohoff, R M, Salter, M W, Schaefer, A, Schafer, D P, Schwartz, M, Simons, M, Smith, C J, Streit, W J, Tay, T L, Tsai, L-H, Verkhratsky, A, von Bernhardi, R, Wake, H, Wittamer, V, Wolf, S A, Wu, L-J & Wyss-Coray, T 2022, ' Microglia states and nomenclature : A field at its crossroads ', Neuron, vol. 110, no. 21, pp. 3458-3483 . https://doi.org/10.1016/j.neuron.2022.10.020
Neuron 110(21), 3458-3483 (2022). doi:10.1016/j.neuron.2022.10.020
Paolicelli, R C, Sierra, A, Stevens, B, Tremblay, M E, Aguzzi, A, Ajami, B, Amit, I, Audinat, E, Bechmann, I, Bennett, M, Bennett, F, Bessis, A, Biber, K, Bilbo, S, Blurton-Jones, M, Boddeke, E, Brites, D, Brône, B, Brown, G C, Butovsky, O, Carson, M J, Castellano, B, Colonna, M, Cowley, S A, Cunningham, C, Davalos, D, De Jager, P L, de Strooper, B, Denes, A, Eggen, B J L, Eyo, U, Galea, E, Garel, S, Ginhoux, F, Glass, C K, Gokce, O, Gomez-Nicola, D, González, B, Gordon, S, Graeber, M B, Greenhalgh, A D, Gressens, P, Greter, M, Gutmann, D H, Haass, C, Heneka, M T, Heppner, F L, Hong, S, Hume, D A, Jung, S, Kettenmann, H, Kipnis, J, Koyama, R, Lemke, G, Lynch, M, Majewska, A, Malcangio, M, Malm, T, Mancuso, R, Masuda, T, Matteoli, M, McColl, B W, Miron, V E, Molofsky, A V, Monje, M, Mracsko, E, Nadjar, A, Neher, J J, Neniskyte, U, Neumann, H, Noda, M, Peng, B, Peri, F, Perry, V H, Popovich, P G, Pridans, C, Priller, J, Prinz, M, Ragozzino, D, Ransohoff, R M, Salter, M W, Schaefer, A, Schafer, D P, Schwartz, M, Simons, M, Smith, C J, Streit, W J, Tay, T L, Tsai, L H, Verkhratsky, A, von Bernhardi, R, Wake, H, Wittamer, V, Wolf, S A, Wu, L J & Wyss-Coray, T 2022, ' Microglia states and nomenclature: A field at its crossroads ', Neuron, vol. 110, no. 21, pp. 3458-3483 . https://doi.org/10.1016/j.neuron.2022.10.020
Neuron, 2022, 110 (21), pp.3458-3483. ⟨10.1016/j.neuron.2022.10.020⟩
Neuron, vol 110, iss 21
Paolicelli, R C, Sierra, A, Stevens, B, Tremblay, M-E, Aguzzi, A, Ajami, B, Amit, I, Audinat, E, Bechmann, I, Bennett, M, Bennett, F, Bessis, A, Biber, K, Bilbo, S, Blurton-Jones, M, Boddeke, E, Brites, D, Brône, B, Brown, G C, Butovsky, O, Carson, M J, Castellano, B, Colonna, M, Cowley, S A, Cunningham, C, Davalos, D, de Jager, P L, de Strooper, B, Denes, A, Eggen, B J L, Eyo, U, Galea, E, Garel, S, Ginhoux, F, Glass, C K, Gokce, O, Gomez-Nicola, D, González, B, Gordon, S, Graeber, M B, Greenhalgh, A D, Gressens, P, Greter, M, Gutmann, D H, Haass, C, Heneka, M T, Heppner, F L, Hong, S, Hume, D A, Jung, S, Kettenmann, H, Kipnis, J, Koyama, R, Lemke, G, Lynch, M, Majewska, A, Malcangio, M, Malm, T, Mancuso, R, Masuda, T, Matteoli, M, McColl, B W, Miron, V E, Molofsky, A V, Monje, M, Mracsko, E, Nadjar, A, Neher, J J, Neniskyte, U, Neumann, H, Noda, M, Peng, B, Peri, F, Perry, V H, Popovich, P G, Pridans, C, Priller, J, Prinz, M, Ragozzino, D, Ransohoff, R M, Salter, M W, Schaefer, A, Schafer, D P, Schwartz, M, Simons, M, Smith, C J, Streit, W J, Tay, T L, Tsai, L-H, Verkhratsky, A, von Bernhardi, R, Wake, H, Wittamer, V, Wolf, S A, Wu, L-J & Wyss-Coray, T 2022, ' Microglia states and nomenclature : A field at its crossroads ', Neuron, vol. 110, no. 21, pp. 3458-3483 . https://doi.org/10.1016/j.neuron.2022.10.020
Neuron 110(21), 3458-3483 (2022). doi:10.1016/j.neuron.2022.10.020
Paolicelli, R C, Sierra, A, Stevens, B, Tremblay, M E, Aguzzi, A, Ajami, B, Amit, I, Audinat, E, Bechmann, I, Bennett, M, Bennett, F, Bessis, A, Biber, K, Bilbo, S, Blurton-Jones, M, Boddeke, E, Brites, D, Brône, B, Brown, G C, Butovsky, O, Carson, M J, Castellano, B, Colonna, M, Cowley, S A, Cunningham, C, Davalos, D, De Jager, P L, de Strooper, B, Denes, A, Eggen, B J L, Eyo, U, Galea, E, Garel, S, Ginhoux, F, Glass, C K, Gokce, O, Gomez-Nicola, D, González, B, Gordon, S, Graeber, M B, Greenhalgh, A D, Gressens, P, Greter, M, Gutmann, D H, Haass, C, Heneka, M T, Heppner, F L, Hong, S, Hume, D A, Jung, S, Kettenmann, H, Kipnis, J, Koyama, R, Lemke, G, Lynch, M, Majewska, A, Malcangio, M, Malm, T, Mancuso, R, Masuda, T, Matteoli, M, McColl, B W, Miron, V E, Molofsky, A V, Monje, M, Mracsko, E, Nadjar, A, Neher, J J, Neniskyte, U, Neumann, H, Noda, M, Peng, B, Peri, F, Perry, V H, Popovich, P G, Pridans, C, Priller, J, Prinz, M, Ragozzino, D, Ransohoff, R M, Salter, M W, Schaefer, A, Schafer, D P, Schwartz, M, Simons, M, Smith, C J, Streit, W J, Tay, T L, Tsai, L H, Verkhratsky, A, von Bernhardi, R, Wake, H, Wittamer, V, Wolf, S A, Wu, L J & Wyss-Coray, T 2022, ' Microglia states and nomenclature: A field at its crossroads ', Neuron, vol. 110, no. 21, pp. 3458-3483 . https://doi.org/10.1016/j.neuron.2022.10.020
Neuron, 2022, 110 (21), pp.3458-3483. ⟨10.1016/j.neuron.2022.10.020⟩
International audience; Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." This dualistic classification of good or bad mi
Autor:
Péter Berki, Csaba Cserép, Zsuzsanna Környei, Balázs Pósfai, Eszter Szabadits, Andor Domonkos, Anna Kellermayer, Miklós Nyerges, Xiaofei Wei, Istvan Mody, Araki Kunihiko, Heinz Beck, He Kaikai, Wang Ya, Nikolett Lénárt, Zhaofa Wu, Miao Jing, Yulong Li, Attila I. Gulyás, Ádám Dénes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Acute brain slices represent a workhorse model for studying the central nervous system (CNS) from nanoscale events to complex circuits. While slice preparation inherently involves tissue damage, it is unclear how microglia, the main immune c
Externí odkaz:
https://doaj.org/article/23b86858b05540109a8a453d5e619efd
Autor:
Yvette Ruska, Andrea Csibi, Beáta Dorogházi, Anett Szilvásy-Szabó, Petra Mohácsik, Zsuzsanna Környei, Ádám Dénes, Andrea Kádár, Zita Puskár, Erik Hrabovszky, Balázs Gereben, Gábor Wittmann, Csaba Fekete
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists are now commonly used to treat type 2 diabetes and obesity. GLP-1R signaling in the spinal cord has been suggested to account for the mild tachycardia caused by GLP-1R agonists, and may also
Externí odkaz:
https://doaj.org/article/d148c75d29844110a7ad30e9a25d1bf6
Autor:
Adam Denes, Lu Xu, Krisztina J. Kovács, Bram Geenen, Nóra Füredi, Márta Balaskó, Christoph Lutter, Balázs Gaszner, Erika Pétervári, Tamas Kozicz
Publikováno v:
Neuropharmacology, 205
Contains fulltext : 249492.pdf (Publisher’s version ) (Open Access) The centrally-projecting Edinger-Westphal nucleus (EWcp) hosts a large population of neurons expressing urocortin 1 (Ucn1) and about half of these neurons also express the leptin r
Autor:
Eszter Tóth, Csaba Cserép, Lilla Turiák, Anett Mázló, György Nagy, Barbara W Sódar, Ágnes Kittel, Attila Bacsi, Katalin Szabó-Taylor, Anna Sebestyén, Yong Song Gho, Zsolt István Komlósi, Adam Denes, András Försönits, Tamás Visnovitz, Gábor Petővári, Edit I. Buzás, László Drahos
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 11, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles
In this study we tested whether a protein corona is formed around extracellular vesicles (EVs) in blood plasma. We isolated medium‐sized nascent EVs of THP1 cells as well as of Optiprep‐purified platelets, and incubated them in EV‐depleted bloo
Autor:
Martina Glavan, Ana Jelic, Damien Levard, Juhana Frösen, Sara Keränen, Bart A. A. Franx, Ana-Rita Bras, Estelle R. Louet, Ádám Dénes, Mario Merlini, Denis Vivien, Marina Rubio
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Intracerebral aneurysms (IAs) are pathological dilatations of cerebral arteries whose rupture leads to subarachnoid hemorrhage, a significant cause of disability and death. Inflammation is recognized as a critical contributor to the formatio
Externí odkaz:
https://doaj.org/article/250903fb87ee47f8a15b4e3395680621
Autor:
Andrea Fekete, Agnes Molnar, Adam Denes, Akos Roland Toth, Tamas Lakat, Adam Hosszu, Éva Mikics, Attila Szabo, Kornél Demeter, Miklós Szabó, Hanga Kelemen
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Perinatal asphyxia (PA) is associated with more than half a million mature newborn deaths yearly. It may lead to severe complications including hypoxic encephalopathy, renal- hepatic- and cardiovascular injury, as well as respirat