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pro vyhledávání: '"Adam D. Hines"'
SummaryGeneral anesthetics disrupt brain network dynamics through multiple pathways, predominately through post-synaptic potentiation of GABAAR and pre-synaptic inhibition of neuroexocytosis. Common clinical general anesthetic drugs, such as propofol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b629e90af49040c72987f8a02bbc0cc
https://doi.org/10.1101/2023.02.27.530184
https://doi.org/10.1101/2023.02.27.530184
Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization
Autor:
Melissa M Mangala, Timothy Y M Ng, Jamie I. Vandenberg, Matthew D. Perry, Adam D Hines, Whitney Liang, Chai Ann Ng, Michelle J O Xu, Adam P. Hill
Publikováno v:
Cardiovascular Research. 116:1434-1445
Aims Current treatment for congenital long QT syndrome Type 2 (cLQTS2), an electrical disorder that increases the risk of life-threatening cardiac arrhythmias, is aimed at reducing the incidence of arrhythmia triggers (beta-blockers) or terminating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7844f9ef082b403fbce3e7d313a1cbac
https://doi.org/10.1093/cvr/cvz247
https://doi.org/10.1093/cvr/cvz247
Autor:
Adam D, Hines, Bruno, van Swinderen
Publikováno v:
eNeuro
Visual Abstract
Super-resolution microscopy provides valuable insight for understanding the nanoscale organization within living tissue, although this method is typically restricted to cultured or dissociated cells. Here, we develop a method to
Super-resolution microscopy provides valuable insight for understanding the nanoscale organization within living tissue, although this method is typically restricted to cultured or dissociated cells. Here, we develop a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::235e15a542f05010a66c16d2536d185b
https://pubmed.ncbi.nlm.nih.gov/33875453
https://pubmed.ncbi.nlm.nih.gov/33875453
Autor:
Adam D Hines, Bruno van Swinderen
Super-resolution microscopy provides valuable insight for understanding the nanoscale organization within living tissue, although this method is typically restricted to cultured or dissociated cells. Here, we develop a method to track the mobility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff84e33d2f7eb07fe8ddd33c02e9140a
https://doi.org/10.1101/2020.09.18.303818
https://doi.org/10.1101/2020.09.18.303818
Autor:
Bruno van Swinderen, Adam D Hines
Publikováno v:
Proceedings of the National Academy of Sciences. 117:24627-24628
A recent study (1) uses Drosophila flies to support a mechanism for general anesthesia. The authors find a specific effect on TWIK-related K+ (TREK-1) channels (a class of potassium leak channels) that results from a nonspecific effect on cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b4b59e8373abe7055e9f8f6c6a9e700
https://doi.org/10.1073/pnas.2012131117
https://doi.org/10.1073/pnas.2012131117
Autor:
Hines, Adam D., Kewin, Amber B., Van De Poll, Matthew N., Anggono, Victor, Bademosi, Adekunle T., van Swinderen, Bruno
Publikováno v:
Journal of Neuroscience; 6/12/2024, Vol. 44 Issue 24, p1-18, 18p
Autor:
Hines, Adam D.
Publikováno v:
Conversation (Conversation Media Group Ltd); 5/17/2024, p6-6, 1p
Autor:
Hines, Adam D., van Swinderen, Bruno
Publikováno v:
eNeuro; May/Jun2021, Vol. 8 Issue 3, p1-13, 13p
Autor:
Perry, Matthew D, Ng, Chai-Ann, Mangala, Melissa M, Ng, Timothy Y M, Hines, Adam D, Liang, Whitney, Xu, Michelle J O, Hill, Adam P, Vandenberg, Jamie I
Publikováno v:
Cardiovascular Research; Jul2020, Vol. 116 Issue 8, p1434-1445, 12p