Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Adam D. Burgener"'
Autor:
Oluwatobiloba A. Taylor, Kenzie D. Birse, D.’Atra J. Hill, Samantha Knodel, Laura Noel-Romas, Anna Myers, Jean Marino, Adam D. Burgener, Rachel Pope, Christina Farr Zuend
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Lichen sclerosus is a chronic inflammatory condition of unknown etiology that affects the genital and extragenital skin, which can lead to sexual dysfunction and has been associated with vulvar cancer. The vaginal microbiome has a critical r
Externí odkaz:
https://doaj.org/article/6897a288acd0439b83b8c9bcb24a33c6
Autor:
Frideborg Bradley, Alexandra Stern, Mathias Franzén Boger, Zaynab Mousavian, Olga Dethlefsen, Vilde Kaldhusdal, Julie Lajoie, Kenneth Omollo, Sofia Bergström, Anna Månberg, Peter Nilsson, Joshua Kimani, Adam D. Burgener, Annelie Tjernlund, Christopher Sundling, Keith R. Fowke, Kristina Broliden
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe cervicovaginal epithelial barrier is crucial for defending the female reproductive tract against sexually transmitted infections. Hormones, specifically estradiol and progesterone, along with their respective receptor expressions, play
Externí odkaz:
https://doaj.org/article/831fc87130c1463bb848812891560e77
Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening
Autor:
Hannah M. Atkins, Aysegul Aksakal Uslu, Jingwei J. Li, Debra A. Shearer, Sarah A. Brendle, Chen Han, Michael Kozak, Paul Lopez, Deesha Nayar, Karla K. Balogh, Catherine Abendroth, Jean Copper, Keith C. Cheng, Neil D. Christensen, Yusheng Zhu, Stefanie Avril, Adam D. Burgener, Thomas T. Murooka, Jiafen Hu
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT A substantial percentage of the population remains at risk for cervical cancer due to pre-existing human papillomavirus (HPV) infections, despite prophylactic vaccines. Early diagnosis and treatment are crucial for better disease outcomes. T
Externí odkaz:
https://doaj.org/article/6e22c5056c51441a99de50ea519d0897
Autor:
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome hav
Externí odkaz:
https://doaj.org/article/1af3ea388c5e4f578c6b6afe6c865734
Autor:
A. R. Berard, T. Hensley-McBain, L. Noël-Romas, K. Birse, M. Abou, G. Westmacott, S. McCorrister, J. Smedley, Nichole R. Klatt, Adam D. Burgener
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract HIV infection damages the gut mucosa leading to chronic immune activation, increased morbidities and mortality, and antiretroviral therapies, do not completely ameliorate mucosal dysfunction. Understanding early molecular changes in acute in
Externí odkaz:
https://doaj.org/article/7f4851aea4284a95ba95c61d0556002d
Autor:
David Jose Delgado-Diaz, Brianna Jesaveluk, Joshua A. Hayward, David Tyssen, Arghavan Alisoltani, Matthys Potgieter, Liam Bell, Elizabeth Ross, Arash Iranzadeh, Imane Allali, Smritee Dabee, Shaun Barnabas, Hoyam Gamieldien, Jonathan M. Blackburn, Nicola Mulder, Steven B. Smith, Vonetta L. Edwards, Adam D. Burgener, Linda-Gail Bekker, Jacques Ravel, Jo-Ann S. Passmore, Lindi Masson, Anna C. Hearps, Gilda Tachedjian
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Women with a cervicovaginal microbiota dominated by Lactobacillus spp. are at reduced risk of acquiring sexually transmitted infections including HIV, but the biological mechanisms involved remain poorly defined. Here, we performe
Externí odkaz:
https://doaj.org/article/0541f19108804ca5b9410ea97a642ff7
Autor:
Alicia R. Berard, Douglas K. Brubaker, Kenzie Birse, Alana Lamont, Romel D. Mackelprang, Laura Noël-Romas, Michelle Perner, Xuanlin Hou, Elizabeth Irungu, Nelly Mugo, Samantha Knodel, Timothy R. Muwonge, Elly Katabira, Sean M. Hughes, Claire Levy, Fernanda L. Calienes, Douglas A. Lauffenburger, Jared M. Baeten, Connie Celum, Florian Hladik, Jairam Lingappa, Adam D. Burgener
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112474- (2023)
Summary: Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, t
Externí odkaz:
https://doaj.org/article/7e7c96530b7143479c58b3f44a85ad62
Autor:
Rachelle N. M. Govia, Kenzie D. Birse, Adam D. Burgener, Vanessa Poliquin, Savas M. Menticoglou, Christy L. Pylypjuk
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 50, Iss 4, p 86 (2023)
Background: We aim to determine the relationship between intra-amniotic sludge and the amniotic fluid proteome in cases of acute cervical insufficiency. Methods: This was a secondary analysis of data from an existing prospective cohort of women with
Externí odkaz:
https://doaj.org/article/4b84e09227614b859f54940e734c3ad7
Autor:
Brian Ferrari, Amanda Cabral Da Silva, Ken H. Liu, Evgeniya V. Saidakova, Larisa B. Korolevskaya, Konstantin V. Shmagel, Carey Shive, Gabriela Pacheco Sanchez, Mauricio Retuerto, Ashish Arunkumar Sharma, Khader Ghneim, Laura Noel-Romas, Benigno Rodriguez, Mahmoud A. Ghannoum, Peter P. Hunt, Steven G. Deeks, Adam D. Burgener, Dean P. Jones, Mirela A. Dobre, Vincent C. Marconi, Rafick-Pierre Sekaly, Souheil-Antoine Younes
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
People living with HIV (PLWH) who are immune nonresponders (INRs) are at greater risk of comorbidity and mortality than are immune responders (IRs) who restore their CD4+ T cell count after antiretroviral therapy (ART). INRs have low CD4+ T cell coun
Externí odkaz:
https://doaj.org/article/2e7dbc6137fc40d5aa924fb147bf5c0a
Autor:
Yiran Wang, Laura Noël-Romas, Michelle Perner, Samantha Knodel, Refilwe Molatlhegi, Sarah Hoger, Kenzie Birse, Christina Farr Zuend, Lyle R McKinnon, Adam D Burgener
Publikováno v:
Clinical Infectious Diseases. 76:1372-1381
Background Adolescent girls and young women aged 15‒24 years in sub-Saharan Africa are at disproportionate risk of human immunodeficiency virus (HIV) infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdee0657ddd93fc4da0949c022811c55
https://doi.org/10.1093/cid/ciac938
https://doi.org/10.1093/cid/ciac938