Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Adam D Cohen"'
Autor:
Nikhil Munshi, Tom Martin, Saad Z Usmani, Jesus Berdeja, Andrzej Jakubowiak, Mounzer Agha, Adam D Cohen, Abhinav Deol, Myo Htut, Alexander Lesokhin, Yi Lin, Elizabeth O’donnell, Carolyn C Jackson, Tzu-Min Yeh, Arnob Banerjee, Enrique Zudaire, Deepu Madduri, Christopher Delcorral, Lida Pacaud, Sundar Jagannath
Publikováno v:
HemaSphere, Vol 7, p e6102468 (2023)
Externí odkaz:
https://doaj.org/article/0953a89f5cd849b38cfb3f30eba6c672
Autor:
Yi Lin, Madhav Dhodapkar, Aaron P Rapoport, Ajai Chari, Nina Shah, Jack Aiello, David E Avigan, Jesus G Berdeja, Ivan M Borrello, Adam D Cohen, Karthik Ganapathi, Lissa Gray, Damian Green, Amrita Krishnan, Elisabet Manasanch, Nikhil C Munshi, Ajay K Nooka, Eric L Smith, Ravi Vij
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Outcomes in multiple myeloma (MM) have improved dramatically in the last two decades with the advent of novel therapies including immunomodulatory agents (IMiDs), proteasome inhibitors and monoclonal antibodies. In recent years, immunotherapy for the
Externí odkaz:
https://doaj.org/article/cfade875c1d0413986d344c84a15d63a
Autor:
Adi Diab, Robert R Jenq, Gabrielle A Rizzuto, Adam D Cohen, Deonka W Huggins, Taha Merghoub, Manuel E Engelhorn, José A Guevara-Patiño, David Suh, Vanessa M Hubbard-Lucey, Adam A Kochman, Suzie Chen, Hong Zhong, Jedd D Wolchok, Marcel R M van den Brink, Alan N Houghton, Miguel-Angel Perales
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82496 (2013)
The development of successful cancer vaccines is contingent on the ability to induce effective and persistent anti-tumor immunity against self-antigens that do not typically elicit immune responses. In this study, we examine the effects of a non-myel
Externí odkaz:
https://doaj.org/article/7e942a7cda4b4992b7f10515a52d9625
Autor:
David A Schaer, Yongbiao Li, Taha Merghoub, Gabrielle A Rizzuto, Amos Shemesh, Adam D Cohen, Yanyun Li, Francesca Avogadri, Ricardo Toledo-Crow, Alan N Houghton, Jedd D Wolchok
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21214 (2011)
Determining how tumor immunity is regulated requires understanding the extent to which the anti-tumor immune response "functions" in vivo without therapeutic intervention. To better understand this question, we developed advanced multimodal reflectan
Externí odkaz:
https://doaj.org/article/f2d885e996e0413bbad0403e80d46321
Autor:
Adam D Cohen, David A Schaer, Cailian Liu, Yanyun Li, Daniel Hirschhorn-Cymmerman, Soo Chong Kim, Adi Diab, Gabrielle Rizzuto, Fei Duan, Miguel A Perales, Taha Merghoub, Alan N Houghton, Jedd D Wolchok
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10436 (2010)
In vivo GITR ligation has previously been shown to augment T-cell-mediated anti-tumor immunity, yet the underlying mechanisms of this activity, particularly its in vivo effects on CD4+ foxp3+ regulatory T cells (Tregs), have not been fully elucidated
Externí odkaz:
https://doaj.org/article/2350e46ba7914c06a03e8005633dff15
Autor:
Alfred L. Garfall, Ehren K. Dancy, Adam D. Cohen, Wei-Ting Hwang, Joseph A. Fraietta, Megan M. Davis, Bruce L. Levine, Don L. Siegel, Edward A. Stadtmauer, Dan T. Vogl, Adam Waxman, Aaron P. Rapoport, Michael C. Milone, Carl H. June, J. Joseph Melenhorst
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2812-2815 (2019)
Externí odkaz:
https://doaj.org/article/c2b1211d1c304b2d96f08de44dae0f46
Autor:
Adam D. Cohen, Alfred L. Garfall, Ahmet Dogan, Simon F. Lacey, Chris Martin, Nikoletta Lendvai, Dan T. Vogl, Matthew Spear, Alexander M. Lesokhin
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2487-2490 (2019)
Externí odkaz:
https://doaj.org/article/5edb8c5900584745961e8dc35d27bd8d
Autor:
Thomas Martin, Saad Z. Usmani, Jesus G. Berdeja, Mounzer Agha, Adam D. Cohen, Parameswaran Hari, David Avigan, Abhinav Deol, Myo Htut, Alexander Lesokhin, Nikhil C. Munshi, Elizabeth O'Donnell, A. Keith Stewart, Jordan M. Schecter, Jenna D. Goldberg, Carolyn C. Jackson, Tzu-Min Yeh, Arnob Banerjee, Alicia Allred, Enrique Zudaire, William Deraedt, Yunsi Olyslager, Changwei Zhou, Lida Pacaud, Deepu Madduri, Andrzej Jakubowiak, Yi Lin, Sundar Jagannath
Publikováno v:
Journal of Clinical Oncology. 41:1265-1274
PURPOSE CARTITUDE-1, a phase Ib/II study evaluating the safety and efficacy of ciltacabtagene autoleucel (cilta-cel) in heavily pretreated patients with relapsed/refractory multiple myeloma, yielded early, deep, and durable responses at 12 months. He
Autor:
Adam D. Cohen, María-Victoria Mateos, Yael C. Cohen, Paula Rodriguez-Otero, Bruno Paiva, Niels W. C. J. van de Donk, Thomas Martin, Attaya Suvannasankha, Kevin C. De Braganca, Christina Corsale, Jordan M. Schecter, Helen Varsos, William Deraedt, Liwei Wang, Martin Vogel, Tito Roccia, Xiaoying Xu, Pankaj Mistry, Enrique Zudaire, Muhammad Akram, Tonia Nesheiwat, Lida Pacaud, Irit Avivi, Jesus San-Miguel
Publikováno v:
Blood, 141(3), 219-230. American Society of Hematology
Cohen, A D, Mateos, M-V, Cohen, Y C, Rodriguez-Otero, P, Paiva, B, van de Donk, N W C J, Martin, T, Suvannasankha, A, de Braganca, K C, Corsale, C, Schecter, J M, Varsos, H, Deraedt, W, Wang, L, Vogel, M, Roccia, T, Xu, X, Mistry, P, Zudaire, E, Akram, M, Nesheiwat, T, Pacaud, L, Avivi, I & San-Miguel, J 2023, ' Efficacy and safety of cilta-cel in patients with progressive multiple myeloma after exposure to other BCMA-targeting agents ', Blood, vol. 141, no. 3, pp. 219-230 . https://doi.org/10.1182/blood.2022015526
Cohen, A D, Mateos, M-V, Cohen, Y C, Rodriguez-Otero, P, Paiva, B, van de Donk, N W C J, Martin, T, Suvannasankha, A, de Braganca, K C, Corsale, C, Schecter, J M, Varsos, H, Deraedt, W, Wang, L, Vogel, M, Roccia, T, Xu, X, Mistry, P, Zudaire, E, Akram, M, Nesheiwat, T, Pacaud, L, Avivi, I & San-Miguel, J 2023, ' Efficacy and safety of cilta-cel in patients with progressive multiple myeloma after exposure to other BCMA-targeting agents ', Blood, vol. 141, no. 3, pp. 219-230 . https://doi.org/10.1182/blood.2022015526
B-cell maturation antigen (BCMA)–targeting therapies, including bispecific antibodies (BsAbs) and antibody-drug conjugates (ADCs), are promising treatments for multiple myeloma (MM), but disease may progress after their use. CARTITUDE-2 is a phase
Autor:
Brian W. Hoeynck, Adam D. Cohen, Edward A. Stadtmauer, Sandra P. Susanibar‐Adaniya, Dan T. Vogl, Adam J. Waxman, Mark Bardsley, Samantha Le, Lexis LaMaestra, Alfred L. Garfall
Publikováno v:
European Journal of Haematology. 110:322-329
Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal demyelinating disease of the central nervous system caused by reactivation of the JC virus in the context of immune suppression such as HIV, malignancy, and certain immunomodu