Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adam D, Hudgins"'
Autor:
Seung-Soo Kim, Adam D. Hudgins, Brenda Gonzalez, Sofiya Milman, Nir Barzilai, Jan Vijg, Zhidong Tu, Yousin Suh
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The rich data from the genome-wide association studies (GWAS) and phenome-wide association studies (PheWAS) offer an unprecedented opportunity to identify the biological underpinnings of age-related disease (ARD) risk and multimorbidity. Surprisingly
Externí odkaz:
https://doaj.org/article/71779d6d6cbd45c3a57de888aa9d604f
Autor:
Seung-Soo Kim, Adam D Hudgins, Jiping Yang, Yizhou Zhu, Zhidong Tu, Michael G Rosenfeld, Teresa P DiLorenzo, Yousin Suh
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257265 (2021)
Type 1 diabetes (T1D) is an organ-specific autoimmune disease, whereby immune cell-mediated killing leads to loss of the insulin-producing β cells in the pancreas. Genome-wide association studies (GWAS) have identified over 200 genetic variants asso
Externí odkaz:
https://doaj.org/article/ef6473d563c743d89291adf7966b5f00
Autor:
Ryan O. Walters, Esperanza Arias, Antonio Diaz, Emmanuel S. Burgos, Fangxia Guan, Simoni Tiano, Kai Mao, Cara L. Green, Yungping Qiu, Hardik Shah, Donghai Wang, Adam D. Hudgins, Tahmineh Tabrizian, Valeria Tosti, David Shechter, Luigi Fontana, Irwin J. Kurland, Nir Barzilai, Ana Maria Cuervo, Daniel E.L. Promislow, Derek M. Huffman
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 663-676.e6 (2018)
Summary: A hallmark of aging is a decline in metabolic homeostasis, which is attenuated by dietary restriction (DR). However, the interaction of aging and DR with the metabolome is not well understood. We report that DR is a stronger modulator of the
Externí odkaz:
https://doaj.org/article/d0b812ca5b9349d5909aebb22098bc5a
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Cellular senescence is a state of irreversible cellular growth arrest accompanied by distinct changes in gene expression and the acquisition of a complex proinflammatory secretory profile termed the senescence-associated secretory phenotype (SASP). S
Externí odkaz:
https://doaj.org/article/1ceb5c740e314b648b391b67ae322504
Autor:
Adam D. Hudgins, Teresa P. DiLorenzo, Yousin Suh, Zhidong Tu, Jiping Yang, Seung Soo Kim, Michael G. Rosenfeld, Yizhou Zhu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257265 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257265 (2021)
Type 1 diabetes (T1D) is an organ-specific autoimmune disease, whereby immune cell-mediated killing leads to loss of the insulin-producing β cells in the pancreas. Genome-wide association studies (GWAS) have identified over 200 genetic variants asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12730d9c24194a45b0104cc9c78f755e
https://doi.org/10.1371/journal.pone.0257265
https://doi.org/10.1371/journal.pone.0257265
Autor:
Adam D. Hudgins
Publikováno v:
Innovation in Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b1f6ae1a2ffa7aac58a2262e3656b0
http://europepmc.org/articles/PMC7742475
http://europepmc.org/articles/PMC7742475
Autor:
Yousin Suh, Adam D. Hudgins
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8036c78c6b6b520d335e74c313f2c5a9
https://doi.org/10.1016/j.jalz.2018.06.2911
https://doi.org/10.1016/j.jalz.2018.06.2911
Publikováno v:
Current opinion in insect science. 6
Drosophila species lack most hallmarks of adaptive immunity yet are highly successful against an array of natural microbial pathogens and metazoan enemies. When attacked by figitid parasitoid wasps, fruit flies deploy robust, multi-faceted innate imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a2461d6e1abc7960961b7a9e1f9b468
https://pubmed.ncbi.nlm.nih.gov/25642411
https://pubmed.ncbi.nlm.nih.gov/25642411