Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adam Cotty"'
Autor:
Brian Tomkowicz, Eileen Walsh, Adam Cotty, Raluca Verona, Nina Sabins, Fred Kaplan, Sandy Santulli-Marotto, Chen-Ni Chin, Jill Mooney, Russell B Lingham, Michael Naso, Timothy McCabe
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140694 (2015)
TIM-3 (T cell immunoglobulin and mucin-domain containing protein 3) is a member of the TIM family of proteins that is preferentially expressed on Th1 polarized CD4+ and CD8+ T cells. Recent studies indicate that TIM-3 serves as a negative regulator o
Externí odkaz:
https://doaj.org/article/e76aef711b9f485fb1a5f0cd9b2692fa
Autor:
Heather Cohen, Cara Bray, Drasti Kanakia, Johanna Lahdenranta, Punit Upadhyaya, Kristen Hurov, Julia Kristensson, Chintan Jobaliya, Greg Bannish, Adam Cotty, Kevin McDonnell, Sandra Hirschberg, Sebastien Hazard, Dominic Smethurst, Nicholas Keen, Stephen J Blakemore
Publikováno v:
Cancer Immunology Research. 10:A65-A65
Bicycles are fully synthetic constrained peptides with antibody-like affinities that target selectively, readily penetrate tumor tissue, have relatively short half-lives, and can be chemically linked together to generate multifunctional molecules. BT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713348767a05a2757f65c43c1c7bd960
https://doi.org/10.1158/2326-6074.tumimm22-a65
https://doi.org/10.1158/2326-6074.tumimm22-a65
Autor:
Heather Cohen, Drasti Kanakia, Johanna Lahdenranta, Punit Upadhyaya, Kristen Hurov, Julia Kristensson, Chintan Jobaliya, Greg Bannish, Adam Cotty, Kevin McDonnell, Sandra Hirschberg, Phil Brandish, Sebastien Hazard, Dominic Smethurst, Nicholas Keen, Stephen J. Blakemore
Publikováno v:
Cancer Research. 82:1976-1976
Bicycles are fully synthetic constrained peptides with antibody-like affinities that target selectively, readily penetrate tumor tissue, have relatively short half-lives, and can be chemically linked together to generate multifunctional molecules. BT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2ec9ddc6083b9ee7d0036d1b5630636
https://doi.org/10.1158/1538-7445.am2022-1976
https://doi.org/10.1158/1538-7445.am2022-1976
Autor:
Jill Giles-Komar, Erin Johnston, Natalie Fursov, Michael A. Rycyzyn, Haiyan Jiang, Gordon Powers, Karen E. Duffy, Jamie Fisher, Theodore Petley, Adam Cotty
Publikováno v:
Hybridoma. 30:153-162
ST2L is a transmembrane receptor that belongs to the IL-1 receptor family. The receptor is expressed on various cell types including Th2 cells, mast cells, basophils, growth-activated fibroblasts, and vascular endothelial cells. ST2L activation by it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584cc867a0af6035d68b074740c82abf
https://doi.org/10.1089/hyb.2010.0100
https://doi.org/10.1089/hyb.2010.0100
Autor:
Russell B. Lingham, Chen Ni Chin, Adam Cotty, Fred Kaplan, Jill Mooney, Michael Naso, Eileen Walsh, Sandy Santulli-Marotto, Raluca Verona, Timothy McCabe, Nina Chi Sabins, Brian E. Tomkowicz
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140694 (2015)
PLoS ONE
PLoS ONE
TIM-3 (T cell immunoglobulin and mucin-domain containing protein 3) is a member of the TIM family of proteins that is preferentially expressed on Th1 polarized CD4+ and CD8+ T cells. Recent studies indicate that TIM-3 serves as a negative regulator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4497610c0035d7e3baf5d4e9ab27e9
http://europepmc.org/articles/PMC4619610?pdf=render
http://europepmc.org/articles/PMC4619610?pdf=render
Autor:
Nachiket Dharker, Carmen G. Lechuga, Marcos Rojkind, Moran Choe, Gregory Desierto, Zamira Hernandez-Nazara, Adam Cotty, Marcia Bustamante, Elizabeth Hernández
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 291:G1051-G1061
Increased expression of PDGF-β receptors is a landmark of hepatic stellate cell activation and transdifferentiation into myofibroblasts. However, the molecular mechanisms that regulate the fate of the receptor are lacking. Recent studies suggested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aeb73391da567683601d596e88ff4be
https://doi.org/10.1152/ajpgi.00058.2005
https://doi.org/10.1152/ajpgi.00058.2005
Autor:
Carmen G. Lechuga, Marcos Rojkind, Ruchi Shah, M. Raj Lakshman, Adam Cotty, Zamira Hernandez-Nazara, Jaime Arellanes-Robledo, Karina Reyes-Gordillo
Publikováno v:
Alcoholism, clinical and experimental research. 37(11)
Background Transforming growth factor beta 1 (TGF-β1) is a pleiotropic cytokine that activates hepatic stellate cell (HSC) proliferation, but inhibits parenchymal cell proliferation. Therefore, we hypothesize that TGF-β1 regulates HSC proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2d2e2e77b2a34f0bd1be83629b6214
https://pubmed.ncbi.nlm.nih.gov/23895226
https://pubmed.ncbi.nlm.nih.gov/23895226
Autor:
Barry Morse, Tina Sauerwald, Heena Beck, Jin Lu, Nancy Peffer, Pam Hawley-Nelson, Jill Carton, Bernard Amegadzie, Ray Sweet, Adam Cotty
Publikováno v:
Protein expression and purification. 55(2)
While well established in bacterial hosts, the effect of coding sequence variation on protein expression in mammalian systems is poorly characterized outside of viral proteins or proteins from distant phylogenetic families. The potential impact is su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a553187a4ce5b4275b06f86ae57fdbf0
https://pubmed.ncbi.nlm.nih.gov/17646110
https://pubmed.ncbi.nlm.nih.gov/17646110
Autor:
Hillary Millar, Haiyan Jiang, Elizabeth Kaiser, Jill Carton, Fred Kaplan, Adam Cotty, Randall J. Brezski, Diana Wiley, E. Christine Pietsch, Allison Oberholtze, Linda A. Snyder, Debbie Marshall, Li Yingzhe, Barry Morse, Michael Naso, Luciana F. Macedo
Publikováno v:
Molecular Cancer Therapeutics. 12:A190-A190
CD24 is a heavily glycosylated glycosylphosphatidylinositol- anchored protein that is overexpressed in many different tumor types, including colon cancer (>80 %), and has been shown to correlate with shortened patient survival. CD24 plays a role in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc4a21985f46e3050e05c45160b5f9f4
https://doi.org/10.1158/1535-7163.targ-13-a190
https://doi.org/10.1158/1535-7163.targ-13-a190